Publication Beamlines Strategic Pillar
Penner, Tiffany V.; Cobo, Neil Lorente; Patel, Deepak T.; Patel, Dhruvin H.; Savchenko, Alexei et al. (2023). Structural characterization of the Sel1‐like repeat protein LceB from Legionella pneumophila. Protein Science . 10.1002/pro.4889. [PDB: 8sxq] CMCF-BM Health
Bailey-Elkin, Ben A.; Knaap, Robert C. M.; De Silva, Anuradha; Boekhoud, Ilse M.; Mous, Sandra et al. (2023). Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis. PLoS Pathogens 19(12) , e1011872. 10.1371/journal.ppat.1011872. [PDB: 8ehn] CMCF-ID Health
Rolando, Monica; Wah Chung, Ivy Yeuk; Xu, Caishuang; Gomez-Valero, Laura; England, Patrick et al. (2023). The SET and ankyrin domains of the secreted Legionella pneumophila histone methyltransferase work together to modify host chromatin. mBio 14(5) . 10.1128/mbio.01655-23. [PDB: 8swi] CMCF-BM Health
Varkaris, Andreas; Pazolli, Ermira; Gunaydin, Hakan; Wang, Qi; Pierce, Levi et al. (2023). Discovery and clinical proof-of-concept of RLY-2608, a first-in-class mutant-selective allosteric PI3Ka inhibitor that decouples anti-tumor activity from hyperinsulinemia. Cancer Discovery . 10.1158/2159-8290.cd-23-0944. [PDB: 8ts7] CMCF-ID Health
Frigon, Léonie; Pascal, John M (2023). Structural and biochemical analysis of the PARP1-homology region of PARP4/vault PARP. Nucleic Acids Research . 10.1093/nar/gkad1064. [PDB: 8sx1] CMCF-BM Health
Kattar, Solomon D.; Gulati, Anmol; Margrey, Kaila A.; Keylor, Mitchell H.; Ardolino, Michael et al. (2023). Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c01486. [PDB: 8six] CMCF-ID Health
Thai, Elaine; Murugan, Rajagopal; Binter, Špela; Burn Aschner, Clare; Prieto, Katherine et al. (2023). Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Reports 42(11) , 113330. 10.1016/j.celrep.2023.113330. [PDB: 8fb5] CMCF-ID Health
Tokareva, Olena S.; Li, Kunhua; Travaline, Tara L.; Thomson, Ty M.; Swiecicki, Jean-Marie et al. (2023). Recognition and reprogramming of E3 ubiquitin ligase surfaces by α-helical peptides. Nature Communications 14(1) . 10.1038/s41467-023-42395-z. [PDB: 8ei4] CMCF-BM Health
Xu, C.; Chung, I.Y.W.; Cygler, M. (2023). Crystal structure of legAS4 from Legionella pneumophila subsp. pneumophila with histone H3 (1-12)peptide. Protein Data Bank: 8swi. CMCF-BM Agriculture
Shahsavan, A.; Gehring, K. (2023). Crystal structure of extracellular domain of CNNM4 from Echinococcus granulosus. Protein Data Bank: 8gk6. CMCF-ID Agriculture
Bailey-Elkin, B.A.; Mark, B.L. (2023). PRRSV-1 PLP2 domain. Protein Data Bank: 8ehn. CMCF-ID Health
Tran, T.T.Q.; Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of human eosinophil-derived neurotoxin (EDN, ribonuclease 2) in complex with 5'-adenosine monophosphate (AMP). Protein Data Bank: 8f5x. CMCF-BM Agriculture
Wang, F.; Cheng, W.; Yuan, Z.; Qi, J.; Shen, Z. et al. (2023). The Crystal Structure of KEAP1 from Biortus.. Protein Data Bank: 8wfg. CMCF-ID Agriculture
Wang, F.; Cheng, W.; Lv, Z.; Guo, S.; Lin, D. et al. (2023). The Crystal Structure of PPARg from Biortus.. Protein Data Bank: 8wfe. CMCF-ID Agriculture
Wang, F.; Cheng, W.; Lv, Z.; Qi, J.; Li, J. et al. (2023). The Crystal Structure of RSK1 from Biortus.. Protein Data Bank: 8wf4. CMCF-ID Agriculture