Publication Beamlines Strategic Pillar
Bryan, Marian C.; Drobnick, Joy; Gobbi, Alberto; Kolesnikov, Aleksandr; Chen, Yongsheng et al. (2019). Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors. Journal of Medicinal Chemistry 62(13) . 10.1021/acs.jmedchem.9b00439. [PDB: 6o9d] CMCF-ID Health
Yu, C.; Drobnick, J.; Bryan, M.C.; Kiefer, J.; Lupardus, P.J. et al. (2019). Structure of the IRAK4 kinase domain with compound 5. Protein Data Bank: 6o9d. CMCF-ID Health
Sack, J.S. (2019). Crystal structure of JAK3 kinase domain in complex with a pyrrolopyridazine carboxamide inhibitor. Protein Data Bank: 6ny4. CMCF-ID Health
Garside, E.L.; MacMillan, A.M. (2019). Prp8 RH domain from C. merolae. Protein Data Bank: 6nqi. CMCF-ID Health
Garside, E.L.; Whelan, T.A.; Stark, M.R.; Rader, S.D.; Fast, N.M. et al. (2019). Prp8 in a Reduced Spliceosome Lacks a Conserved Toggle that Correlates with Splicing Complexity across Diverse Taxa. Journal of Molecular Biology 431(14) . 10.1016/j.jmb.2019.04.047. [PDB: 6nqi] CMCF-ID Health
Fenalti, G. (2019). Crystal structure of the human TTK in complex with an inhibitor. Protein Data Bank: 6n6o. CMCF-ID Health
Riggs, Jennifer R.; Elsner, Jan; Cashion, Dan; Robinson, Dale; Tehrani, Lida et al. (2019). Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy. Journal of Medicinal Chemistry 62(9) , 4401-4410. 10.1021/acs.jmedchem.8b01869. [PDB: 6n6o] CMCF-ID Health
Caveney, N.A.; Strynadka, N.C.J. (2019). Crystal structure of GIL01 gp7. Protein Data Bank: 6n7o. CMCF-BM Health
Tamura, K.; Gardill, B.R.; Brumer, H.; Van Petegem, F. (2019). Bacteroides ovatus mixed-linkage glucan utilization locus (MLGUL) SGBP-B in complex with mixed-linkage heptasaccharide. Protein Data Bank: 6e9b. CMCF-BM Health
Tamura, Kazune; Foley, Matthew H.; Gardill, Bernd R.; Dejean, Guillaume; Schnizlein, Matthew et al. (2019). Surface glycan-binding proteins are essential for cereal beta-glucan utilization by the human gut symbiont Bacteroides ovatus. Cellular and Molecular Life Sciences 76(21) . 10.1007/s00018-019-03115-3. [PDB: 6e9b] CMCF-BM Health
Halgas, O.; Zarabi, S.F.; Schimmer, A.; Pai, E.F. (2019). Human mitochondrial ClpP in complex with ONC201 (TIC10). Protein Data Bank: 6dl7. CMCF-ID Health
Ishizawa, Jo; Zarabi, Sarah F.; Davis, R. Eric; Halgas, Ondrej; Nii, Takenobu et al. (2019). Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality. Cancer Cell 35(5) . 10.1016/j.ccell.2019.03.014. [PDB: 6dl7] CMCF-ID Health
van Petegem, F.; Haji-Ghassemi, O. (2019). Catalytic subunit of cAMP-dependent protein kinase A in complex with RyR2 K2879A, S2813D phosphomimetic (2699-2904) crystal form 1. Protein Data Bank: 6mm7. CMCF-BM Health
van Petegem, F.; Haji-Ghassemi, O. (2019). Catalytic subunit of cAMP-dependent protein kinase A in complex with RyR2 phosphorylation domain (2699-2904). Protein Data Bank: 6mm6. CMCF-BM Health
Lei, M.; Tempel, W.; Arrowsmith, C.H.; Bountra, C.; Edwards, A.M. et al. (2019). MeCP2 MBD in complex with DNA. Protein Data Bank: 6ogj. CMCF-ID Health