Publication Beamlines Strategic Pillar
McDougall, Matthew; Francisco, Olga; Harder-Viddal, Candice; Roshko, Roy; Meier, Markus et al. (2017). Archaea S-layer nanotube from a “black smoker” in complex with cyclo-octasulfur (S 8 ) rings. Proteins: Structure. Function and Bioinformatics 85(12) , 2209-2216. 10.1002/prot.25385. CMCF-BM Health
McLeod, B.; Scally, S.W.; Bosch, A.; King, C.R.; Julien, J.P. et al. (2017). Crystal structure of Pfs25 in complex with the transmission blocking antibody 1262. Protein Data Bank: 6b0h. CMCF-ID Health
McLeod, B.; Scally, S.W.; Bosch, A.; King, C.R.; Julien, J.P. et al. (2017). Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245. Protein Data Bank: 6b0g. CMCF-ID Health
Min, X.; Wang, Z. (2017). Crystal structure of growth differentiation factor. Protein Data Bank: 5vt2. CMCF-ID Health
Park, Jaeok; Rodionov, Dmitry; De Schutter, Joris W.; Lin, Yih-Shyan; Tsantrizos, Youla S. et al. (2017). Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase. PLoS ONE 12(10) , e0186447. 10.1371/journal.pone.0186447. [PDB: 4nfi, 4nfj, 4nfk] CMCF-ID Health
Pawluk, April; Shah, Megha; Mejdani, Marios; Calmettes, Charles; Moraes, Trevor F. et al. (2017). Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein. mBio 8(6) , e01751-17. 10.1128/mbio.01751-17. [PDB: 6arz, 6as4] CMCF-BM Health
Picard, M.-E.; Cusson, M.; Shi, R. (2017). Crystal structure of CfFPPS2, a lepidopteran type-II farnesyl diphosphate synthase, complexed with IPP and [2-(1-methylpyridin-2-yl)-1-phosphono-ethyl]phosphonic acid (inhibitor 1b). Protein Data Bank: 6b06. CMCF-ID Agriculture
Picard, M.-E.; Cusson, M.; Shi, R. (2017). Crystal structure of CfFPPS2, a lepidopteran type-II farnesyl diphosphate synthase, complexed with [2-(1-methylpyridin-2-yl)-1-phosphono-ethyl]phosphonic acid (inhibitor 1b). Protein Data Bank: 6b04. CMCF-ID Agriculture
Picard, M.-E.; Cusson, M.; Shi, R. (2017). Crystal structure of CfFPPS2 (apo form), a lepidopteran type-II farnesyl diphosphate synthase. Protein Data Bank: 6b02. CMCF-ID Agriculture
Rai, Ganesha; Brimacombe, Kyle R.; Mott, Bryan T.; Urban, Daniel J.; Hu, Xin et al. (2017). Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). Journal of Medicinal Chemistry 60(22) , 9184-9204. 10.1021/acs.jmedchem.7b00941. [PDB: 5w8h, 5w8j] CMCF-ID Health
Ravulapalli, R.; Heney, K.; Ebeling, J.; Genersch, E.; Merrill, A.R. et al. (2017). Plx2a, an ADP-ribosyltransferase toxin from Paenibacillus larvae. Protein Data Bank: 5urp. CMCF-ID Health
Riggs, Jennifer R.; Nagy, Mark; Elsner, Jan; Erdman, Paul; Cashion, Dan et al. (2017). The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen. Journal of Medicinal Chemistry 60(21) , 8989-9002. 10.1021/acs.jmedchem.7b01223. [PDB: 6b4w] CMCF-ID Health
Scally, Stephen W.; McLeod, Brandon; Bosch, Alexandre; Miura, Kazutoyo; Liang, Qi et al. (2017). Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nature Communications 8(1) . 10.1038/s41467-017-01924-3. [PDB: 6azz, 6b08, 6b0a, 6b0e, 6b0g, 6b0h] CMCF-ID Health
Scally, Stephen W.; Murugan, Rajagopal; Bosch, Alexandre; Triller, Gianna; Costa, Giulia et al. (2017). Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection. Journal of Experimental Medicine 215(1) , 63-75. 10.1084/jem.20170869. [PDB: 6b0s, 6b0w] CMCF-ID Health
Scally, S.W.; Bosch, A.; Triller, G.; Wardemann, H.; Julien, J.P. et al. (2017). Crystal structure of the neutralizing anti-circumsporozoite protein 663 antibody. Protein Data Bank: 6azx. CMCF-ID Health