| Zhang, Heng; Zhou, Bo; Qin, Su; Xu, Jing; Harding, Rachel et al. (2018). Structural and functional analysis of the DOT1L–AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis. Genes & Development 32(5-6) , 341-346. 10.1101/gad.311639.118. [PDB: 6cko] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Zhang, H.; Tempel, W.; Bountra, C.; Arrowsmith, C.H.; Edwards, A.M. et al. (2018). Crystal structure of an AF10 fragment. Protein Data Bank: 6cko. |
CMCF-ID |
PDB Deposition |
Health |
| Dementiev, A.A.; Partridge, J.R. (2018). Structures of the two-chain human plasma Factor XIIa co-crystallized with potent inhibitors. Protein Data Bank: 6b74. |
CMCF-ID |
PDB Deposition |
Health |
| Dementiev, Alexey; Silva, Abel; Yee, Calvin; Li, Zhe; Flavin, Michael T. et al. (2018). Structures of human plasma β–factor XIIa cocrystallized with potent inhibitors. Blood advances 2(5) , 549-558. 10.1182/bloodadvances.2018016337. [PDB: 6b74] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Reid, Joel W.; Kaduk, James A.; Matei, Lidia (2018). The crystal structure of MoO2(O2)H2O. Powder Diffraction 33(1) , 49-54. 10.1017/s0885715618000118. |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Lakshminarasimhan, D.; White, A.; Nadupalli, A.; Suto, R.K. (2018). Glycogen Synthase Kinase 3 beta Complexed with BRD3731. Protein Data Bank: 5kpm. |
CMCF-ID |
PDB Deposition |
Health |
| Lakshminarasimhan, D.; White, A.; Nadupalli, A.; Suto, R.K. (2018). Glycogen Synthase Kinase 3 beta Complexed with BRD0705. Protein Data Bank: 5kpl. |
CMCF-ID |
PDB Deposition |
Health |
| Wagner, Florence F.; Benajiba, Lina; Campbell, Arthur J.; Weïwer, Michel; Sacher, Joshua R. et al. (2018). Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Science Translational Medicine 10(431) , eaam8460. 10.1126/scitranslmed.aam8460. [PDB: 5kpl, 5kpm] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Pandit, J. (2018). Structure of human monoacylglycerol lipase bound to a covalent inhibitor. Protein Data Bank: 6bq0. |
CMCF-ID |
PDB Deposition |
Health |
| McAllister, Laura A.; Butler, Christopher R.; Mente, Scot; O’Neil, Steven V.; Fonseca, Kari R. et al. (2018). Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. Journal of Medicinal Chemistry 61(7) , 3008-3026. 10.1021/acs.jmedchem.8b00070. [PDB: 6bq0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Xu, Chao; Liu, Ke; Lei, Ming; Yang, Ally; Li, Yanjun et al. (2018). DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure 26(1) , 85-95.e3. 10.1016/j.str.2017.11.022. [PDB: 5w9q] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Vance, Tyler D.R.; Graham, Laurie A.; Davies, Peter L. (2018). An ice‐binding and tandem beta‐sandwich domain‐containing protein in
Shewanella frigidimarina
is a potential new type of ice adhesin. FEBS Journal 285(8) , 1511-1527. 10.1111/febs.14424. [PDB: 6bg8] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Dranow, D.M.; Abendroth, J.; Lorimer, D.D. (2018). Crystal Structure of Human Lysyl-tRNA Synthetase complexed with L-Lysylsulfamoyl Adenosine. Protein Data Bank: 6chd. |
CMCF-ID |
PDB Deposition |
Health |
| Hedges, Jason B.; Kuatsjah, Eugene; Du, Yi-Ling; Eltis, Lindsay D.; Ryan, Katherine S. et al. (2018). Snapshots of the Catalytic Cycle of an O2, Pyridoxal Phosphate-Dependent Hydroxylase. ACS Chemical Biology 13(4) , 965-974. 10.1021/acschembio.8b00039. [PDB: 6c3a, 6c3b, 6c3c, 6c3d] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Vance, T.D.R.; Davies, P.L. (2018). Shewanella frigidimarina ice-binding protein_1 DUF3494 Domain. Protein Data Bank: 6bg8. |
CMCF-BM |
PDB Deposition |
Health |