Publication Beamlines Strategic Pillar
Trempe, Jean-François; Sauvé, Véronique; Grenier, Karl; Seirafi, Marjan; Tang, Matthew Y. et al. (2013). Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation. Science 340(6139) , 1451-1455. 10.1126/science.1237908. [PDB: 4k7d] CMCF-ID Health
van Kasteren, Puck B.; Bailey-Elkin, Ben A.; James, Terrence W.; Ninaber, Dennis K.; Beugeling, Corrine et al. (2013). Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells. Proceedings of the National Academy of Sciences of the United States of America 110(9) , E838-E847. 10.1073/pnas.1218464110. [PDB: 4ium] CMCF-ID Health
van Straaten, Karin E.; Ko, Jong Bum; Jagdhane, Rajendra; Anjum, Shazia; Palmer, David R.J. et al. (2013). The Structure of NtdA, a Sugar Aminotransferase Involved in the Kanosamine Biosynthetic Pathway in Bacillus subtilis, Reveals a New Subclass of Aminotransferases. Journal of Biological Chemistry 288(47) , 34121-34130. 10.1074/jbc.m113.500637. [PDB: 4k2b, 4k2i, 4k2m] CMCF-ID Health
Vinaik, Roohi; Kozlov, Guennadi; Gehring, Kalle (2013). Structure of the Non-Catalytic Domain of the Protein Disulfide Isomerase-Related Protein (PDIR) Reveals Function in Protein Binding. PLoS ONE 8(4) , e62021. 10.1371/journal.pone.0062021. CMCF-ID Health
Von Kreudenstein, Thomas Spreter; Escobar-Carbrera, Eric; Lario, Paula I.; D’Angelo, Igor; Brault, Karine et al. (2013). Improving biophysical properties of a bispecific antibody scaffold to aid developability. mAbs 5(5) , 646-654. 10.4161/mabs.25632. [PDB: 4bsv, 4bsw] CMCF-BM Health
Wheatley, Robert W.; Lo, Summie; Jancewicz, Larisa J.; Dugdale, Megan L.; Huber, Reuben E. et al. (2013). Structural Explanation for Allolactose (lac Operon Inducer) Synthesis by lacZ β-Galactosidase and the Evolutionary Relationship between Allolactose Synthesis and the lac Repressor. Journal of Biological Chemistry 288(18) , 12993-13005. 10.1074/jbc.m113.455436. [PDB: 4duw, 4dux] CMCF-BM Health
Wu, Hong; Siarheyeva, Alena; Zeng, Hong; Lam, Robert; Dong, Aiping et al. (2013). Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2. FEBS Letters 587(23) , 3859-3868. 10.1016/j.febslet.2013.10.020. [PDB: 3s8p] CMCF-ID Health
Wu, Hong; Zeng, Hong; Dong, Aiping; Li, Fengling; He, Hao et al. (2013). Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations. PLoS ONE 8(12) , e83737. 10.1371/journal.pone.0083737. [PDB: 4mi0] CMCF-ID Health
Zhang, Xiaolu Linda; Tibbits, Glen F.; Paetzel, Mark (2013). The structure of cardiac troponin C regulatory domain with bound Cd2+reveals a closed conformation and unique ion coordination. Acta Crystallographica Section D Biological Crystallography 69(5) , 722-734. 10.1107/s0907444913001182. [PDB: 3sd6, 4gje, 4gjf, 4gjg] CMCF-BM, CMCF-ID Health
Zheng, Hongyan; Bertwistle, Drew; Sanders, David A. R.; Palmer, David R. J. (2013). Converting NAD-Specific Inositol Dehydrogenase to an Efficient NADP-Selective Catalyst, with a Surprising Twist. Biochemistry 52(34) , 5876-5883. 10.1021/bi400821s. [PDB: 4l8v, 4l9r] CMCF-ID Health
Zheng, Xiaozhang; Bair, Kenneth W.; Bauer, Paul; Baumeister, Timm; Bowman, Krista K. et al. (2013). Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorganic and Medicinal Chemistry Letters 23(20) , 5488-5497. 10.1016/j.bmcl.2013.08.074. [PDB: 4lva] CMCF-ID Health
Zhu, Xueyong; Yu, Wenli; McBride, Ryan; Li, Yan; Chen, Li-Mei et al. (2013). Hemagglutinin homologue from H17N10 bat influenza virus exhibits divergent receptor-binding and pH-dependent fusion activities. Proceedings of the National Academy of Sciences of the United States of America 110(4) , 1458-1463. 10.1073/pnas.1218509110. [PDB: 4i78] CMCF-ID Health