Ren, Li; Grina, Jonas; Moreno, David; Blake, James F.; Gaudino, John J. et al. (2015). Discovery of Highly Potent, Selective, and Efficacious Small Molecule Inhibitors of ERK1/2. Journal of Medicinal Chemistry 58(4) , 1976-1991. 10.1021/jm501921k. [PDB: 4xj0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Bacik, John-Paul; Klesmith, Justin R.; Whitehead, Timothy A.; Jarboe, Laura R.; Unkefer, Clifford J. et al. (2015). Producing Glucose 6-Phosphate from Cellulosic Biomass. Journal of Biological Chemistry 290(44) , 26638-26648. 10.1074/jbc.m115.674614. [PDB: 4yh5, 4zfv, 4zlu, 5bsb] |
CMCF-ID |
Peer-Reviewed Article |
Agriculture |
Baral, Pravas Kumar; Swayampakula, Mridula; Aguzzi, Adriano; James, Michael N.G. (2015). X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. Journal of Structural Biology 192(1) , 37-47. 10.1016/j.jsb.2015.08.014. [PDB: 4yx2] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Bamford, Natalie C.; Snarr, Brendan D.; Gravelat, Fabrice N.; Little, Dustin J.; Lee, Mark J. et al. (2015). Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus. Journal of Biological Chemistry 290(46) , 27438-27450. 10.1074/jbc.m115.679050. [PDB: 5d6t] |
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Health |
Xu, Chao; Li, Zhihong; He, Hao; Wernimont, Amy; Li, Yanjun et al. (2015). Crystal structure of human nuclear pore complex component NUP43. FEBS Letters 589(21) , 3247-3253. 10.1016/j.febslet.2015.09.008. [PDB: 4i79] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Ndubaku, Chudi O.; Crawford, James J.; Drobnick, Joy; Aliagas, Ignacio; Campbell, David et al. (2015). Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pKa Polar Moiety. ACS Medicinal Chemistry Letters 6(12) , 1241-1246. 10.1021/acsmedchemlett.5b00398. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Robb, Melissa; Robb, Craig S.; Higgins, Melanie A.; Hobbs, Joanne K.; Paton, James C. et al. (2015). A Second β-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans. Journal of Biological Chemistry 290(52) , 30888-30900. 10.1074/jbc.m115.688630. [PDB: 5a6a, 5a6b, 5a6k, 5ac5] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Zhao, Jianbao; Liu, Zhenxian; Reid, Joel; Takarabe, Kenichi; Iida, Tsutomu et al. (2015). Thermoelectric and electrical transport properties of Mg2Si multi-doped with Sb, Al and Zn. Journal of Materials Chemistry A 3(39) , 19774-19782. 10.1039/c5ta03751d. |
CMCF-BM |
Peer-Reviewed Article |
Materials |
Shi, Qiaojuan; Straus, Marco R.; Caron, Jeremy J.; Wang, Huasheng; Chung, Yu Seon et al. (2015). Conformational toggling controls target site choice for the heteromeric transposase element Tn7. Nucleic Acids Research 43(22) , 10734-10745. 10.1093/nar/gkv913. [PDB: 5d16] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Baker, Perrin; Whitfield, Gregory B.; Hill, Preston J.; Little, Dustin J.; Pestrak, Matthew J. et al. (2015). Characterization of the Pseudomonas aeruginosa Glycoside Hydrolase PslG Reveals That Its Levels Are Critical for Psl Polysaccharide Biosynthesis and Biofilm Formation. Journal of Biological Chemistry 290(47) , 28374-28387. 10.1074/jbc.m115.674929. [PDB: 5bxa] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Yuchi, Zhiguang; Yuen, Siobhan M. Wong King; Lau, Kelvin; Underhill, Ainsley Q.; Cornea, Razvan L. et al. (2015). Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant. Nature Communications 6(1) . 10.1038/ncomms8947. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Ravulapalli, Ravikiran; Lugo, Miguel R.; Pfoh, Roland; Visschedyk, Danielle; Poole, Amanda et al. (2015). Characterization of Vis Toxin, a Novel ADP-Ribosyltransferase from Vibrio splendidus. Biochemistry 54(38) , 5920-5936. 10.1021/acs.biochem.5b00921. [PDB: 4y1w, 4yc0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Gregg, Katie J.; Suits, Michael D.L.; Deng, Lehua; Vocadlo, David J.; Boraston, Alisdair B. et al. (2015). Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights into Its Mechanism. Journal of Biological Chemistry 290(42) , 25657-25669. 10.1074/jbc.m115.680470. |
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Peer-Reviewed Article |
Health |
D’Costa, Vanessa M.; Braun, Virginie; Landekic, Marija; Shi, Rong; Proteau, Ariane et al. (2015). Salmonella Disrupts Host Endocytic Trafficking by SopD2-Mediated Inhibition of Rab7. Cell Reports 12(9) , 1508-1518. 10.1016/j.celrep.2015.07.063. [PDB: 5cq9] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Wan, Honghe; Schroeder, Gretchen M.; Hart, Amy C.; Inghrim, Jennifer; Grebinski, James et al. (2015). Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms. ACS Medicinal Chemistry Letters 6(8) , 850-855. 10.1021/acsmedchemlett.5b00226. [PDB: 5cf8] |
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