| Wang, F.; Cheng, W.; Shang, H.; Wang, R.; Zhang, B. et al. (2021). The Crystal Structure of human MTH1 from Biortus. Protein Data Bank: 7esf. |
CMCF-ID |
PDB Deposition |
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| Wang, F.; Cheng, W.; Xu, C.; Qi, J.; Bao, X. et al. (2021). The Crystal Structure of human DHFR from Biortus. Protein Data Bank: 7ese. |
CMCF-ID |
PDB Deposition |
Health |
| Nolte, R.T.; Somers, D.O.; Gampe, R.T. (2021). H-PDGS complexed with a 2-phenylimidazo[1,2-a]pyridine-6-carboxamide inhibitors. Protein Data Bank: 7jr6. |
CMCF-ID |
PDB Deposition |
Health |
| Schulte, Christie A.; Deaton, David N.; Diaz, Elsie; Do, Young; Gampe, Robert T. et al. (2021). A knowledge-based, structural-aided discovery of a novel class of 2-phenylimidazo[1,2-a]pyridine-6-carboxamide H-PGDS inhibitors. Bioorganic and Medicinal Chemistry Letters 47, 128113. 10.1016/j.bmcl.2021.128113. [PDB: 7jr6] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Klein, D.J.; Beshore, D.C. (2021). STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH APICIDIN. Protein Data Bank: 7ltg. |
CMCF-ID |
PDB Deposition |
Health |
| Beshore, Douglas C.; Adam, Gregory C.; Barnard, Richard J. O.; Burlein, Christine; Gallicchio, Steven N. et al. (2021). Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction. ACS Medicinal Chemistry Letters 12(4) , 540-547. 10.1021/acsmedchemlett.1c00074. [PDB: 7ltg] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Hu, Carol H.; Neissel Valente, Meriah W.; Halpern, O. Scott; Jusuf, Sutjano; Khan, Javed A. et al. (2021). Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO). Bioorganic and Medicinal Chemistry Letters 42, 128010. 10.1016/j.bmcl.2021.128010. [PDB: 7lag, 7lan] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Dorsey, B.W.; Swinger, K.K.; Schenkel, L.B.; Church, W.D.; Perl, N.R. et al. (2021). Human PARP14 (ARTD8), catalytic fragment in complex with RBN012042. Protein Data Bank: 7l9y. |
CMCF-ID |
PDB Deposition |
Health |
| Wigle, Tim J.; Ren, Yue; Molina, Jennifer R.; Blackwell, Danielle J.; Schenkel, Laurie B. et al. (2021). Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule. ChemBioChem 22(12) . 10.1002/cbic.202100047. [PDB: 7l9y] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Palte, R.L.; Hayes, R.P. (2021). PRMT5:MEP50 Complexed with 5,5-Bicyclic Inhibitor Compound 4. Protein Data Bank: 7kib. |
CMCF-ID |
PDB Deposition |
Health |
| Quiroz, Ryan V.; Reutershan, Michael H.; Schneider, Sebastian E.; Sloman, David; Lacey, Brian M. et al. (2021). The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer. Journal of Medicinal Chemistry 64(7) , 3911-3939. 10.1021/acs.jmedchem.0c02083. [PDB: 7kib] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Davies, Christopher W.; Stowe, Irma; Phung, Qui T.; Ho, Hoangdung; Bakalarski, Corey E. et al. (2021). Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function. Proceedings of the National Academy of Sciences of the United States of America 118(12) , e2018024118. 10.1073/pnas.2018024118. [PDB: 7jwq] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Wang, F.; Xu, C.; Qi, J.; Zhang, M.; Tian, F. et al. (2021). The Crystal Structure of D-psicose-3-epimerase from Biortus.. Protein Data Bank: 7e9w. |
CMCF-ID |
PDB Deposition |
Health |
| Wang, F.; Lin, D.; Wang, R.; Wei, X.; Shen, Z. et al. (2021). The Crystal Structure of human UMP-CMP kinase from Biortus.. Protein Data Bank: 7e9v. |
CMCF-ID |
PDB Deposition |
Health |
| Sintchak, M.; Lane, W.; Bump, N. (2021). Structure of SUMO1-ML786519 adduct bound to SAE. Protein Data Bank: 6xog. |
CMCF-ID |
PDB Deposition |
Health |