Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). Structure of methyltransferase RedM that forms the dimethylpyrrolinium of the bisindole reductasporine. Journal of Biological Chemistry 300(1) , 105520. 10.1016/j.jbc.2023.105520. |
CMCF |
Peer-Reviewed Article |
Health |
Petraccione, Kaylee; Ali, Mohamed G. H.; Cyr, Normand; Wahba, Haytham M.; Stocker, Timothy et al. (2024). An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy. PLoS Pathogens 20(3) , e1012093. 10.1371/journal.ppat.1012093. [PDB: 8t2m] |
CMCF-BM |
Peer-Reviewed Article |
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Shurtleff, Valerie W.; Layton, Mark E.; Parish, Craig A.; Perkins, James J.; Schreier, John D. et al. (2024). Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c02248. [PDB: 8ute] |
CMCF-BM |
Peer-Reviewed Article |
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Penner, Tiffany V.; Cobo, Neil Lorente; Patel, Deepak T.; Patel, Dhruvin H.; Savchenko, Alexei et al. (2023). Structural characterization of the Sel1‐like repeat protein LceB from Legionella pneumophila. Protein Science . 10.1002/pro.4889. [PDB: 8sxq] |
CMCF-BM |
Peer-Reviewed Article |
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Li, Franco K. K.; Worrall, Liam J.; Gale, Robert T.; Brown, Eric D.; Strynadka, Natalie C. J. et al. (2024). Cryo-EM analysis of
S. aureus
TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance. Science advances 10(9) . 10.1126/sciadv.adj3864. [PDB: 8v33] |
CMCF-ID |
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Ketcham, John M.; Harwood, Stephen J.; Aranda, Ruth; Aloiau, Athenea N.; Bobek, Briana M. et al. (2024). Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c00078. [PDB: 8v8h] |
CMCF-ID |
Peer-Reviewed Article |
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Puumala, Emily; Sychantha, David; Lach, Elizabeth; Reeves, Shawn; Nabeela, Sunna et al. (2024). Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity. Cell Chemical Biology . 10.1016/j.chembiol.2024.01.010. [PDB: 8uk6] |
CMCF-ID |
Peer-Reviewed Article |
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Folger, Ines B.; Frota, Natália F.; Pistofidis, Angelos; Niquille, David L.; Hansen, Douglas A. et al. (2024). High-throughput reprogramming of an NRPS condensation domain. Nature Chemical Biology . 10.1038/s41589-023-01532-x. [PDB: 8f7f] |
CMCF-ID |
Peer-Reviewed Article |
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Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). An imine reductase that captures reactive intermediates in the biosynthesis of the indolocarbazole reductasporine. Journal of Biological Chemistry , 105642. 10.1016/j.jbc.2024.105642. |
CMCF-ID |
Peer-Reviewed Article |
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Wang, F.; Cheng, W.; Lv, Z.; Meng, Q.; Xu, Y. et al. (2024). The Crystal Structure of NF-kB-inducing Kinase (NIK) from Biortus. Protein Data Bank: 8yhw. |
CMCF-BM |
PDB Deposition |
Health |
Wang, F.; Cheng, W.; Lv, Z.; Meng, Q.; Xu, Y. et al. (2024). The Crystal Structure of Tgf-Beta Type I Receptor (Alk5) from Biortus. Protein Data Bank: 8yhl. |
CMCF-BM |
PDB Deposition |
Health |
Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Wang, J. et al. (2024). The Crystal Structure of TGF beta R2 kinase domain from Biortus.. Protein Data Bank: 8ygz. |
CMCF-BM |
PDB Deposition |
Health |
Xu, C.; Chung, I.Y.W.; Cygler, M. (2024). Crystal structure of legAS4 from Legionella pneumophila subsp. pneumophila with histone H3 (3-17)peptide. Protein Data Bank: 8sr6. |
CMCF-BM |
PDB Deposition |
Health |
Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Bao, C. et al. (2024). The Crystal Structure of USP8 from Biortus.. Protein Data Bank: 8y9a. |
CMCF-BM |
PDB Deposition |
Health |
Krishnamurthy, H.; Zhuang, N.; Qiang, D.; Wu, Y.; Klein, D.J. et al. (2024). Structure of SARS-Cov2 3CLPro in complex with Compound 27. Protein Data Bank: 8ute. |
CMCF-BM |
PDB Deposition |
Health |