Grochulski, Pawel; Labiuk, Shaunivan (2021). Review of health research at the Canadian Light Source. Nuclear Instruments and Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms 499, 70-76. 10.1016/j.nimb.2021.05.003. |
BIOXAS, BMIT, CMCF, MID-IR, SM, SXRMB, VESPERS |
Peer-Reviewed Article |
Health |
Grochulski, Pawel; Labiuk, Shaunivan (2021). Review of health research at the Canadian Light Source. Nuclear Instruments and Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms 499, 70-76. 10.1016/j.nimb.2021.05.003. |
BIOXAS, BMIT, CMCF, MID-IR, SM, SXRMB, VESPERS |
Peer-Reviewed Article |
Health |
Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). Structure of methyltransferase RedM that forms the dimethylpyrrolinium of the bisindole reductasporine. Journal of Biological Chemistry 300(1) , 105520. 10.1016/j.jbc.2023.105520. |
CMCF |
Peer-Reviewed Article |
Health |
van Vliet, Vera J. E.; Huynh, Nhan; Palà, Judith; Patel, Ankoor; Singer, Alex et al. (2022). Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site. PLoS Pathogens 18(12) , e1011065. 10.1371/journal.ppat.1011065. |
CMCF |
Peer-Reviewed Article |
Health |
Grochulski, Pawel; Labiuk, Shaunivan (2021). Review of health research at the Canadian Light Source. Nuclear Instruments and Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms 499, 70-76. 10.1016/j.nimb.2021.05.003. |
BIOXAS, BMIT, CMCF, MID-IR, SM, SXRMB, VESPERS |
Peer-Reviewed Article |
Health |
Kozlov, Guennadi; Funato, Yosuke; Chen, Yu Seby; Zhang, Zhidian; Illes, Katalin et al. (2020). PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth. Journal of Biological Chemistry 295(33) , 11682-11692. 10.1074/jbc.ra120.014464. |
CMCF |
Peer-Reviewed Article |
Health |
Petraccione, Kaylee; Ali, Mohamed G. H.; Cyr, Normand; Wahba, Haytham M.; Stocker, Timothy et al. (2024). An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy. PLoS Pathogens 20(3) , e1012093. 10.1371/journal.ppat.1012093. [PDB: 8t2m] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Shurtleff, Valerie W.; Layton, Mark E.; Parish, Craig A.; Perkins, James J.; Schreier, John D. et al. (2024). Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c02248. [PDB: 8ute] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Xu, Shangyi; Grochulski, Pawel; Tanaka, Takuji (2024). Structural basis for the allosteric behaviour and substrate specificity of Lactococcus lactis Prolidase. Biochimica et Biophysica Acta - Proteins and Proteomics 1872(3) , 141000. 10.1016/j.bbapap.2024.141000. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Penner, Tiffany V.; Cobo, Neil Lorente; Patel, Deepak T.; Patel, Dhruvin H.; Savchenko, Alexei et al. (2023). Structural characterization of the Sel1‐like repeat protein LceB from Legionella pneumophila. Protein Science . 10.1002/pro.4889. [PDB: 8sxq] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Smith, Christopher R.; Chen, Dan; Christensen, James G.; Coulombe, René; Féthière, James et al. (2023). Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. Journal of Medicinal Chemistry 67(1) , 774-781. 10.1021/acs.jmedchem.3c02140. [PDB: 8t5g, 8t5m, 8t5r] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Rolando, Monica; Wah Chung, Ivy Yeuk; Xu, Caishuang; Gomez-Valero, Laura; England, Patrick et al. (2023). The SET and ankyrin domains of the secreted
Legionella pneumophila
histone methyltransferase work together to modify host chromatin. mBio 14(5) . 10.1128/mbio.01655-23. [PDB: 8swi] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Frigon, Léonie; Pascal, John M (2023). Structural and biochemical analysis of the PARP1-homology region of PARP4/vault PARP. Nucleic Acids Research . 10.1093/nar/gkad1064. [PDB: 8sx1] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Tokareva, Olena S.; Li, Kunhua; Travaline, Tara L.; Thomson, Ty M.; Swiecicki, Jean-Marie et al. (2023). Recognition and reprogramming of E3 ubiquitin ligase surfaces by α-helical peptides. Nature Communications 14(1) . 10.1038/s41467-023-42395-z. [PDB: 8ei4] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Pérez-Vargas, Jimena; Worrall, Liam J.; Olmstead, Andrea D.; Ton, Anh-Tien; Lee, Jaeyong et al. (2023). A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerging Microbes and Infections 12(2) . 10.1080/22221751.2023.2246594. [PDB: 8cyu, 8cyz, 8sxr] |
CMCF-BM |
Peer-Reviewed Article |
Health |