Publication Beamlines Strategic Pillar
Hu, Zilun; Wang, Cailan; Glunz, Peter W.; Li, Julia; Cheadle, Nathan L. et al. (2020). Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies. Bioorganic and Medicinal Chemistry Letters 30(21) , 127495. 10.1016/j.bmcl.2020.127495. [PDB: 7jou] CMCF-ID Health
Jones, Carys S.; Sychantha, David; Howell, P. Lynne; Clarke, Anthony J. (2020). Structural basis for the O-acetyltransferase function of the extracytoplasmic domain of OatA from Staphylococcus aureus. Journal of Biological Chemistry 295(24) , jbc.RA120.013108. 10.1074/jbc.ra120.013108. [PDB: 6wn9] CMCF-BM Health
Jones, Darryl R.; Xing, Xiaohui; Tingley, Jeffrey P.; Klassen, Leeann; King, Marissa L. et al. (2020). Analysis of Active Site Architecture and Reaction Product Linkage Chemistry Reveals a Conserved Cleavage Substrate for an Endo-alpha-mannanase within Diverse Yeast Mannans. Journal of Molecular Biology 432(4) , 1083-1097. 10.1016/j.jmb.2019.12.048. [PDB: 6u4z] CMCF-BM Agriculture
Kozlov, Guennadi; Funato, Yosuke; Chen, Yu Seby; Zhang, Zhidian; Illes, Katalin et al. (2020). PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth. Journal of Biological Chemistry 295(33) , 11682-11692. 10.1074/jbc.ra120.014464. CMCF Health
Li, Franco K.K.; Rosell, Federico I.; Gale, Robert T.; Simorre, Jean-Pierre; Brown, Eric D. et al. (2020). Crystallographic analysis of Staphylococcus aureus LcpA, the primary wall teichoic acid ligase. Journal of Biological Chemistry 295(9) , 2629-2639. 10.1074/jbc.ra119.011469. [PDB: 6uex, 6uf3, 6uf5, 6uf6] CMCF-ID Health
Liu, Jian; Yu, Younong; Kelly, Joseph; Sha, Deyou; Alhassan, Abdul-Basit et al. (2020). Discovery of Highly Selective and Potent HDAC3 Inhibitors Based on a 2-Substituted Benzamide Zinc Binding Group. ACS Medicinal Chemistry Letters 11(12) , 2476-2483. 10.1021/acsmedchemlett.0c00462. [PDB: 7kbg] CMCF-ID Health
Lu, Xiaocen; Wen, Yurong; Zhang, Shuce; Zhang, Wei; Chen, Yilun et al. (2020). Improved Photocleavable Proteins with Faster and More Efficient Dissociation. Journal of Nanoparticle Research . 10.1101/2020.12.10.419556. [PDB: 7dmx, 7dna, 7dnb] CMCF-ID Health
Majdi Yazdi, Mohadeseh; Saran, Sagar; Mrozowich, Tyler; Lehnert, Cheyanne; Patel, Trushar R. et al. (2020). Asparagine-84, a regulatory allosteric site residue, helps maintain the quaternary structure of Campylobacter jejuni dihydrodipicolinate synthase. Journal of Structural Biology 209(1) . 10.1016/j.jsb.2019.107409. [PDB: 6tzu, 6u01] CMCF-BM, CMCF-ID Health
Manenda, Mahder S.; Picard, Marie-Ève; Zhang, Liping; Cyr, Normand; Zhu, Xiaojun et al. (2020). Structural analyses of the Group A flavin-dependent monooxygenase PieE reveal a sliding FAD cofactor conformation bridging OUT and IN conformations. Journal of Biological Chemistry 295(14) , jbc.RA119.011212. 10.1074/jbc.ra119.011212. [PDB: 6u0p, 6u0s] CMCF-ID Health
Mascle, Xavier H.; Gagnon, Christina; Wahba, Haytham M.; Lussier-Price, Mathieu; Cappadocia, Laurent et al. (2020). Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner. Structure 28(2) . 10.1016/j.str.2019.11.019. [PDB: 6uyo, 6uyp, 6uyq, 6uyr, 6uyu, 6uyz] CMCF-ID Health
Mendoza, Matthew N.; Jian, Mike; King, Moeko T.; Brooks, Cory L. (2020). Role of a noncanonical disulfide bond in the stability, affinity, and flexibility of a VHH specific for the Listeria virulence factor InlB. Protein Science 29(4) , 1004-1017. 10.1002/pro.3831. [PDB: 6u12, 6u14] CMCF-ID Health
Miersch, Shane; Li, Zhijie; Saberianfar, Reza; Ustav, Mart; Case, James Brett et al. (2020). Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations. Vibrational Spectroscopy . 10.1101/2020.10.31.362848. [PDB: 7klg, 7klh] CMCF-BM Health
Miron, Caitlin E.; Staalduinen, Laura; Rangaswamy, Alana M.; Chen, Mickey; Liang, Yushi et al. (2020). Going Platinum to the Tune of a Remarkable Guanine Quadruplex Binder: Solution‐ and Solid‐State Investigations.. Angewandte Chemie - International Edition 60(5) . 10.1002/anie.202012520. [PDB: 6xcl] CMCF-BM Health
Mitcheltree, Matthew J.; Li, Derun; Achab, Abdelghani; Beard, Adam; Chakravarthy, Kalyan et al. (2020). Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. ACS Medicinal Chemistry Letters 11(4) , 582-588. 10.1021/acsmedchemlett.0c00058. [PDB: 6v7c] CMCF-ID Health
Murugan, Rajagopal; Scally, Stephen W.; Costa, Giulia; Mustafa, Ghulam; Thai, Elaine et al. (2020). Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs. Nature Medicine 26(7) . 10.1038/s41591-020-0881-9. [PDB: 6ulf] CMCF-ID Health