Publication Beamlines Strategic Pillar
Wilding, Birgit; Scharn, Dirk; Böse, Dietrich; Baum, Anke; Santoro, Valeria et al. (2022). Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling. Nature Cancer 3(7) , 821-836. 10.1038/s43018-022-00412-y. [PDB: 7pcd] CMCF-ID Health
Taylor, Alexander M.; Bailey, Chris; Belmont, Lisa D.; Campbell, Robert; Cantone, Nico et al. (2022). GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1. Journal of Medicinal Chemistry 65(16) , 11177-11186. 10.1021/acs.jmedchem.2c00662. [PDB: 7td9] CMCF-ID Health
Tang, Y.; Poy, F.; Taylor, A.M.; Cochran, A.G.; Bellon, S.F. et al. (2022). G-059 bound to the SMARCA4 (BRG1) Bromodomain. Protein Data Bank: 7td9. CMCF-ID Agriculture
Suits, M.D.L. (2022). Bfo2294: Tannerella forsythia 2-Keto-3-deoxy-6-phosphogluconate aldolase (KDPG) and 4-Hydroxy-2-oxoglutarate aldolase (KHG). Protein Data Bank: 8di1. CMCF-ID Agriculture
Suits, M.D.L. (2022). Bfo2290: Tannerella forsythia chondroitin sulfate A sulfatase. Protein Data Bank: 8di0. CMCF-BM Agriculture
Sharon, I.; Schmeing, T.M. (2022). Pseudobacteroides cellulosolvens pseudo-CphB. Protein Data Bank: 7uqv. CMCF-BM Agriculture
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2022). Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase, MurC) Pseudomonas aeruginosa in complex with ligand AZ-13643701. Protein Data Bank: 8egn. CMCF-BM Agriculture
Saurette, Emily M.; Frinfrock, Y. Zou; Verbuyst, Brent; Blowes, David W.; McBeth, Joyce M. et al. (2022). Improved precision in As speciation analysis with HERFD-XANES at the As K-edge: the case of As speciation in mine waste. Journal of Synchrotron Radiation 29(5) , 1198-1208. 10.1107/s1600577522007068. CMCF-BM Environment
Pollock, G.L., Grishin, A.M., Giogha, C., Gan, J., Oates, C.V.L., McMillan, P.J., Gaeta, I., Tyska, M.J., Pearson, J.S., Scott, N.E., Cygler, M., Hartland, E.L. (2022). EPS8 SH3 Domain with NleH1 PxxDY Motif. Protein Data Bank: 7tzk. CMCF-BM Agriculture
Pollock, Georgina L.; Grishin, Andrey M.; Giogha, Cristina; Gan, Jiyao; Oates, Clare V. et al. (2022). Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli. Proceedings of the National Academy of Sciences of the United States of America 119(34) . 10.1073/pnas.2204332119. [PDB: 7tzk] CMCF-BM Health
Niu, Xun; Foster, E. Johan; Patrick, Brian O.; Rojas, Orlando J. (2022). Betulin Self‐Assembly: From High Axial Aspect Crystals to Hedgehog Suprastructures. Advanced Functional Materials 32(44) , 2206058. 10.1002/adfm.202206058. CMCF-BM Materials
Nguyen, Peter; Eshaque, Rony; Garland, Barbara Anne; Dang, Anthony; Suits, Michael D. L. et al. (2022). Degradation of chondroitin sulfate A by a PUL-like operon in Tannerella forsythia. PLoS ONE 17(9) , e0272904. 10.1371/journal.pone.0272904. [PDB: 8di0, 8di1] CMCF-BM, CMCF-ID Health
Lewis, H.A.; Muckelbauer, J.K. (2022). CRYSTAL STRUCTURE OF HIV-1 INTEGRASE COMPLEXED WITH (2S)-2-(TERT-BUTOXY)-2-(5-{2-[(2-CHLORO-6-M ETHYLPHENYL)METHYL]-1,2,3,4-TETRAHYDROISOQUINOLIN-6-YL}-4- (4,4-DIMETHYLPIPERIDIN-1-YL)-2-METHYLPYRIDIN-3-YL)ACETIC ACID. Protein Data Bank: 7uoq. CMCF-ID Health
Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Structure of SARS-CoV-2 Mpro in complex with nsp12-nsp13 (C12) cut site sequence. Protein Data Bank: 8ds1. CMCF-BM Health
Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp10-nsp11 (C10) cut site sequence (form 2). Protein Data Bank: 8drx. CMCF-BM Health