Publication Beamlines Strategic Pillar
Adachi, Kaoru; Manabe, Tomoyuki; Yamasaki, Takayuki; Suma, Akira; Orita, Takuya et al. (2024). Design and synthesis of novel and potent allosteric HIV-1 integrase inhibitors with a spirocyclic moiety. Bioorganic and Medicinal Chemistry Letters 110, 129864. 10.1016/j.bmcl.2024.129864. [PDB: 8zh4] CMCF-ID Health
Depp, Charles T.; Goodman, Aaron J.; Blanchard, Peter.E.R.; Massimi, Scott E.; Reid, Joel W. et al. (2024). Potential for high-grade recovery of rare earth elements and cobalt from acid mine drainage via adsorption to precipitated manganese (IV) oxides. Chemosphere , 143144. 10.1016/j.chemosphere.2024.143144. BIOXAS-MAIN, CMCF-BM Environment
Després, Philippe C.; Dubé, Alexandre K.; Picard, Marie-Ève; Grenier, Jordan; Shi, Rong et al. (2024). Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science 385(6710) , 770-775. 10.1126/science.ado5719. [PDB: 8vll, 8vlm] CMCF-BM, CMCF-ID Health
Golisch, Benedikt; Cordeiro, Rosa Lorizolla; Fraser, Alexander S.C.; Briggs, Jonathon; Stewart, William A. et al. (2024). The molecular basis of cereal mixed-linkage β-glucan utilization by the human gut bacterium Segatella copri. Journal of Biological Chemistry 300(9) , 107625. 10.1016/j.jbc.2024.107625. [PDB: 9bal, 9bmk] CMCF-ID Health
Gruninger, Robert J.; Kevorkova, Maya; Low, Kristin E.; Jones, Darryl R.; Worrall, Liam et al. (2024). Structural, Biochemical, and Phylogenetic Analysis of Bacterial and Fungal Carbohydrate Esterase Family 15 Glucuronoyl Esterases in the Rumen. Protein Journal 43(4) , 910-922. 10.1007/s10930-024-10221-0. [PDB: 8tru, 8trx, 8tse] CMCF-ID Health
Hsiao, Yi-Chun; Wallweber, Heidi Ackerly; Alberstein, Robert G.; Lin, Zhonghua; Du, Changchun et al. (2024). Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining. Nature Communications 15(1) . 10.1038/s41467-024-52442-y. [PDB: 8t59] CMCF-ID Health
Ireland, Kendra A.; Kayrouz, Chase M.; Abbott, Marissa L.; Seyedsayamdost, Mohammad R.; Davis, Katherine M. et al. (2024). Structural insights into the convergent evolution of sulfoxide synthase EgtB-IV, an ergothioneine-biosynthetic homolog of ovothiol synthase OvoA. Structure . 10.1016/j.str.2024.08.006. [PDB: 8vig, 8vih] CMCF-ID Health
Kassardjian, Audrey; Ivanochko, Danton; Barber, Brian; Jetha, Arif; Julien, Jean-Philippe et al. (2024). Humanization of Pan-HLA-DR mAb 44H10 Hinges on Critical Residues in the Antibody Framework. Antibodies 13(3) , 57. 10.3390/antib13030057. [PDB: 9b7b] CMCF-ID Health
Lin, Funing; Mabanglo, Mark F.; Zhou, Jin Lin; Binepal, Gursonika; Barghash, Marim M. et al. (2024). Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases. Journal of Medicinal Chemistry 67(17) , 15131-15147. 10.1021/acs.jmedchem.4c00773. [PDB: 8szm, 8szn] CMCF-BM Health
Saran, Anshu; Kim, Hey-Min; Manning, Ireland; Hancock, Mark A; Schmitz, Claus et al. (2024). Unveiling the molecular mechanisms of the type IX secretion system's response regulator: Structural and functional insights. PNAS Nexus 3(8) . 10.1093/pnasnexus/pgae316. [PDB: 8ted] CMCF-BM Health
Sauvé, Véronique; Stefan, Eric; Croteau, Nathalie; Goiran, Thomas; Fakih, Rayan et al. (2024). Activation of parkin by a molecular glue. Nature Communications 15(1) . 10.1038/s41467-024-51889-3. [PDB: 8w31] CMCF-ID Health
Schoepfer, Valerie A.; Jamieson, Heather E.; Lindsay, Matthew B.J. (2024). Arsenic mineral and compound data as analyzed by X-ray absorption spectroscopy and X-ray diffraction. Data in Brief 55, 110634. 10.1016/j.dib.2024.110634. BIOXAS-MAIN, BXDS-WHE, CMCF-BM Environment
Schroeter, Kurt L.; Rolfe, Nicolas; Forrester, Taylor J.B.; Kimber, Matthew S.; Seah, Stephen Y.K. et al. (2024). Shy is a proteobacterial steroid hydratase which catalyzes steroid side chain degradation without requiring a catalytically inert partner domain. Journal of Biological Chemistry 300(8) , 107509. 10.1016/j.jbc.2024.107509. [PDB: 8vwr] CMCF-ID Health
Shrimpton, Heather K.; Ptacek, Carol J.; Blowes, David W. (2024). Selenite Stable Isotope Fractionation during Abiotic Reduction by Sodium Sulfide. Environmental Science & Technology . 10.1021/acs.est.4c03607. CMCF-BM Environment
Tian, Yuqing; Worrall, Liam J.; Sim, Lyann; Liu, Feng; Nasseri, Seyed A. et al. (2024). Cobalt as a Cofactor for α-Galactosaminidase-Catalyzed Cleavage of Blood Group Antigens. ACS Catalysis 14(17) , 13497-13508. 10.1021/acscatal.4c03643. [PDB: 9awt, 9ay8, 9ayu] CMCF-BM, CMCF-ID Health