Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). Structure of methyltransferase RedM that forms the dimethylpyrrolinium of the bisindole reductasporine. Journal of Biological Chemistry 300(1) , 105520. 10.1016/j.jbc.2023.105520. |
CMCF |
Peer-Reviewed Article |
Health |
Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). An imine reductase that captures reactive intermediates in the biosynthesis of the indolocarbazole reductasporine. Journal of Biological Chemistry , 105642. 10.1016/j.jbc.2024.105642. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Folger, Ines B.; Frota, Natália F.; Pistofidis, Angelos; Niquille, David L.; Hansen, Douglas A. et al. (2024). High-throughput reprogramming of an NRPS condensation domain. Nature Chemical Biology . 10.1038/s41589-023-01532-x. [PDB: 8f7f] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Ketcham, John M.; Harwood, Stephen J.; Aranda, Ruth; Aloiau, Athenea N.; Bobek, Briana M. et al. (2024). Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c00078. [PDB: 8v8h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Li, Franco K. K.; Worrall, Liam J.; Gale, Robert T.; Brown, Eric D.; Strynadka, Natalie C. J. et al. (2024). Cryo-EM analysis of
S. aureus
TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance. Science advances 10(9) . 10.1126/sciadv.adj3864. [PDB: 8v33] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Petraccione, Kaylee; Ali, Mohamed G. H.; Cyr, Normand; Wahba, Haytham M.; Stocker, Timothy et al. (2024). An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy. PLoS Pathogens 20(3) , e1012093. 10.1371/journal.ppat.1012093. [PDB: 8t2m] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Puumala, Emily; Sychantha, David; Lach, Elizabeth; Reeves, Shawn; Nabeela, Sunna et al. (2024). Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity. Cell Chemical Biology . 10.1016/j.chembiol.2024.01.010. [PDB: 8uk6] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Shurtleff, Valerie W.; Layton, Mark E.; Parish, Craig A.; Perkins, James J.; Schreier, John D. et al. (2024). Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c02248. [PDB: 8ute] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Ali, M.G.H.; Wahba, H.M.; Cyr, N.; Omichinski, J.G. (2024). Crystal structure of GABARAP in complex with the LIR of NSs4. Protein Data Bank: 8t2m. |
CMCF-BM |
PDB Deposition |
Agriculture |
Bar Ziv, T.; Zhang, D.; Tomlinson, A.C.A.; Knox, J.E.; Yano, J.K. et al. (2024). Tricomplex of RMC-7977, KRAS G12R, and CypA. Protein Data Bank: 8tbh. |
CMCF-ID |
PDB Deposition |
Health |
Brooks, C.L.; Aguilar, E.N. (2024). Crystal Structure of the Humanized MUC16 Specific Antibody huAR9.6. Protein Data Bank: 8gkl. |
CMCF-ID |
PDB Deposition |
Health |
Brooks, C.L.; Murray, B. (2024). Crystal Structure of the Humanized MUC16 Specific Antibody huAR9.6. Protein Data Bank: 8gkk. |
CMCF-ID |
PDB Deposition |
Health |
Chen, A.; Tomlinson, A.C.A.; Knox, J.E.; Yano, J.K. (2024). Tricomplex of RMC-7977, HRAS WT, and CypA. Protein Data Bank: 8tbg. |
CMCF-ID |
PDB Deposition |
Health |
Critton, D.A. (2024). Crystal structure of monkey TLR7 ectodomain with compound 14. Protein Data Bank: 8s9h. |
CMCF-ID |
PDB Deposition |
Health |
Dhindwal, P.; Ruzzini, A. (2024). Bile salt hydrolase from Arthrobacter citreus with covalent inhibitor AAA-10 bound. Protein Data Bank: 8vsy. |
CMCF-ID |
PDB Deposition |
Health |