Publication Beamlines Strategic Pillar
Johnson, Ted W.; Richardson, Paul F.; Bailey, Simon; Brooun, Alexei; Burke, Benjamin J. et al. (2014). Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations. Journal of Medicinal Chemistry 57(11) , 4720-4744. 10.1021/jm500261q. [PDB: 4ctb] CMCF-ID Health
Khozeimeh Sarbisheh, Elaheh; Green, Jennifer C.; Müller, Jens (2014). Isomerization of an Enantiomerically Pure Phosphorus-Bridged [1]Ferrocenophane. Organometallics 33(13) , 3508-3513. 10.1021/om500424m. CMCF-BM Materials
Kimlicka, Lynn (2014). Structural and biochemical characterizations of the skeletal muscle and cardiac ryanodine receptor N-terminal disease-associated mutants. Supervisor: Van Petegem, Filip. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/46392. CMCF-ID Health
King, D.T.; Strynadka, N.C.J. (2014). LpoB C-terminal domain from Salmonella enterica (Native). Protein Data Bank: 4q6l. CMCF-BM Health
King, D.T.; Strynadka, N.C.J. (2014). LpoB C-terminal domain from Escherichia coli. Protein Data Bank: 4q6z. CMCF-BM Health
King, D.T.; Strynadka, N.C.J. (2014). LpoB C-terminal domain from Salmonella enterica (Sel-Met). Protein Data Bank: 4q6v. CMCF-BM Health
Loewen, Peter C.; Carpena, Xavi; Vidossich, Pietro; Fita, Ignacio; Rovira, Carme et al. (2014). An Ionizable Active-Site Tryptophan Imparts Catalase Activity to a Peroxidase Core. Journal of the American Chemical Society 136(20) , 7249-7252. 10.1021/ja502794e. [PDB: 5syh, 5syk] CMCF-ID Health
McTigue, M.A.; Deng, Y.L.; Liu, W.; Brooun, A.; Stewart, A.E. et al. (2014). Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor (5R)-8-amino-3-fluoro-5,19-dimethyl-20-oxo-5,18,19,20- tetrahydro-7,11-(azeno)pyrido(2',1':2,3)imidazo(4,5-h)(2,5,11) benzoxadiazacyclotetradecine-14-carbonitrile. Protein Data Bank: 4ctb. CMCF-ID Health
Oh, Angela; Ho, Yen-Ching; Zak, Mark; Liu, Yongbo; Chen, Xukun et al. (2014). Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase. ChemBioChem 15(8) , 1121-1130. 10.1002/cbic.201402023. [PDB: 4o0z, 4o10] CMCF-ID Health
Oh, A.; Wang, W. (2014). Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase. Protein Data Bank: 4o0z. CMCF-ID Health
Oh, A.; Wang, W. (2014). Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase. Protein Data Bank: 4o10. CMCF-ID Health
Park, J.; Leung, C.Y.; Tsantrizos, Y.S.; Berghuis, A.M. (2014). Crystal structure of human FPPS in complex with CL03093. Protein Data Bank: 4lph. CMCF-ID Health
Park, J.; Leung, C.Y.; Tsantrizos, Y.S.; Berghuis, A.M. (2014). Crystal structure of human FPPS in complex with CL01131. Protein Data Bank: 4lpg. CMCF-ID Health
Persch, E.; Bryson, S.; Pai, E.F.; Krauth-Siegel, R.L.; Diederich, F. et al. (2014). Crystal structure of Trypanothione Reductase from Trypanosoma brucei in complex with inhibitor EP127 (5-{5-[1-(PYRROLIDIN-1-YL)CYCLOHEXYL]-1,3-THIAZOL-2-YL}-1H-INDOLE). Protein Data Bank: 4nev. CMCF-ID Health
Persch, Elke; Bryson, Steve; Todoroff, Nickolay K.; Eberle, Christian; Thelemann, Jonas et al. (2014). Binding to Large Enzyme Pockets: Small-Molecule Inhibitors of Trypanothione Reductase. ChemMedChem , 1880-1891. 10.1002/cmdc.201402032. [PDB: 4nev] CMCF-BM Health