Publication Beamlines Strategic Pillar
Zheng, Xiaozhang; Bair, Kenneth W.; Bauer, Paul; Baumeister, Timm; Bowman, Krista K. et al. (2013). Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorganic and Medicinal Chemistry Letters 23(20) , 5488-5497. 10.1016/j.bmcl.2013.08.074. [PDB: 4lva] CMCF-ID Health
Wu, Hong; Siarheyeva, Alena; Zeng, Hong; Lam, Robert; Dong, Aiping et al. (2013). Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2. FEBS Letters 587(23) , 3859-3868. 10.1016/j.febslet.2013.10.020. [PDB: 3s8p] CMCF-ID Health
Iancu, Cristina V.; Zamoon, Jamillah; Woo, Sang Bum; Aleshin, Alexander; Choe, Jun-yong et al. (2013). Crystal structure of a glucose/H + symporter and its mechanism of action. Proceedings of the National Academy of Sciences of the United States of America 110(44) , 17862-17867. 10.1073/pnas.1311485110. CMCF-ID Health
van Straaten, Karin E.; Ko, Jong Bum; Jagdhane, Rajendra; Anjum, Shazia; Palmer, David R.J. et al. (2013). The Structure of NtdA, a Sugar Aminotransferase Involved in the Kanosamine Biosynthetic Pathway in Bacillus subtilis, Reveals a New Subclass of Aminotransferases. Journal of Biological Chemistry 288(47) , 34121-34130. 10.1074/jbc.m113.500637. [PDB: 4k2b, 4k2i, 4k2m] CMCF-ID Health
Wu, Hong; Zeng, Hong; Dong, Aiping; Li, Fengling; He, Hao et al. (2013). Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations. PLoS ONE 8(12) , e83737. 10.1371/journal.pone.0083737. [PDB: 4mi0] CMCF-ID Health
Hong, Minsun; Lee, Peter S.; Hoffman, Ryan M. B.; Zhu, Xueyong; Krause, Jens C. et al. (2013). Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site. Journal of Virology 87(22) , 12471-12480. 10.1128/jvi.01388-13. [PDB: 4m5z] CMCF-ID Health
Hoover, Gordon J.; Jørgensen, René; Rochon, Amanda; Bajwa, Vikramjit S.; Merrill, A. Rod et al. (2013). Identification of catalytically important amino acid residues for enzymatic reduction of glyoxylate in plants. Biochimica et Biophysica Acta - Proteins and Proteomics 1834(12) , 2663-2671. 10.1016/j.bbapap.2013.09.013. CMCF-ID Agriculture
Leung, Chun Yuen; Park, Jaeok; De Schutter, Joris W.; Sebag, Michael; Berghuis, Albert M. et al. (2013). Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition. Journal of Medicinal Chemistry 56(20) , 7939-7950. 10.1021/jm400946f. [PDB: 4jvj, 4l2x] CMCF-ID Health
Dalrymple, Sean A.; Ko, John; Sheoran, Inder; Kaminskyj, Susan G. W.; Sanders, David A. R. et al. (2013). Elucidation of Substrate Specificity in Aspergillus nidulans UDP-Galactose-4-Epimerase. PLoS ONE 8(10) , e76803. 10.1371/journal.pone.0076803. [PDB: 4lis] CMCF-ID Health