Publication Beamlines Strategic Pillar
Bacik, John-Paul; Whitworth, Garrett E.; Stubbs, Keith A.; Vocadlo, David J.; Mark, Brian L. et al. (2012). Active Site Plasticity within the Glycoside Hydrolase NagZ Underlies a Dynamic Mechanism of Substrate Distortion. Chemistry & Biology 19(11) , 1471-1482. 10.1016/j.chembiol.2012.09.016. [PDB: 4gvf, 4gvg, 4gvh, 4gyj, 4gyk] CMCF-ID Health
Baral, Pravas Kumar; Wieland, Barbara; Swayampakula, Mridula; Polymenidou, Magdalini; Rahman, Muhammad Hafiz et al. (2012). Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1. Acta Crystallographica Section D Biological Crystallography 68(11) , 1501-1512. 10.1107/s0907444912037328. [PDB: 4dgi] CMCF-ID Health
Chong, Pek; Sebahar, Paul; Youngman, Michael; Garrido, Dulce; Zhang, Huichang et al. (2012). Rational Design of Potent Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase. Journal of Medicinal Chemistry 55(23) , 10601-10609. 10.1021/jm301294g. [PDB: 2yni] CMCF-ID Health
Cotelesage, Julien J. H.; Grochulski, Pawel; Pickering, Ingrid J.; George, Graham N.; Fodje, Michel N. et al. (2012). X-ray absorption spectroscopy at a protein crystallography facility: the Canadian Light Source beamline 08B1-1. Journal of Synchrotron Radiation 19(6) , 887-891. 10.1107/s090904951204023x. CMCF-BM Materials
Epstein, Linda F.; Chen, Hao; Emkey, Renee; Whittington, Douglas A. (2012). The R1275Q Neuroblastoma Mutant and Certain ATP-competitive Inhibitors Stabilize Alternative Activation Loop Conformations of Anaplastic Lymphoma Kinase. Journal of Biological Chemistry 287(44) , 37447-37457. 10.1074/jbc.m112.391425. [PDB: 4fnz] CMCF-ID Health
Gomery, Kathryn; Müller-Loennies, Sven; Brooks, Cory L.; Brade, Lore; Kosma, Paul et al. (2012). Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS. Proceedings of the National Academy of Sciences of the United States of America 109(51) , 20877-20882. 10.1073/pnas.1209253109. [PDB: 3v0w] CMCF-ID Health
Grishin, Andrey M.; Ajamian, Eunice; Zhang, Linhua; Rouiller, Isabelle; Bostina, Mihnea et al. (2012). Protein-Protein Interactions in the β-Oxidation Part of the Phenylacetate Utilization Pathway. Journal of Biological Chemistry 287(45) , 37986-37996. 10.1074/jbc.m112.388231. [PDB: 4fzw] CMCF-ID Health
Hehemann, Jan-Hendrik; Kelly, Amelia G.; Pudlo, Nicholas A.; Martens, Eric C.; Boraston, Alisdair B. et al. (2012). Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes. Proceedings of the National Academy of Sciences of the United States of America 109(48) , 19786-19791. 10.1073/pnas.1211002109. [PDB: 4aw7] CMCF-ID Health
Jha, Vikash; Chelikani, Prashen; Carpena, Xavi; Fita, Ignacio; Loewen, Peter C. et al. (2012). Influence of main channel structure on H2O2 access to the heme cavity of catalase KatE of Escherichia coli. Archives of Biochemistry and Biophysics 526(1) , 54-59. 10.1016/ [PDB: 4enp, 4enr, 4ens, 4ent, 4enu, 4env, 4enw] CMCF-ID Health
Loewen, Peter C.; Didychuk, Allison L.; Switala, Jacek; Perez-Luque, Rosa; Fita, Ignacio et al. (2012). Structure ofPisum sativumRubisco with bound ribulose 1,5-bisphosphate. Acta Crystallographica Section F Structural Biology and Crystallization Communications 69(1) , 10-14. 10.1107/s1744309112047549. [PDB: 4hhh, 4mkv] CMCF-ID Health
MacFarlane, Ainsley A.; Orriss, George; Okun, Natalie; Meier, Markus; Klonisch, Thomas et al. (2012). The Pentameric Channel of COMPcc in Complex with Different Fatty Acids. PLoS ONE 7(11) , e48130. 10.1371/journal.pone.0048130. [PDB: 3v2n, 3v2p, 3v2q] CMCF-ID Health
Pfoh, Roland; Li, Angela; Chakrabarti, Nilmadhab; Payandeh, Jian; Pomès, Régis et al. (2012). Structural asymmetry in the magnesium channel CorA points to sequential allosteric regulation. Proceedings of the National Academy of Sciences of the United States of America 109(46) , 18809-18814. 10.1073/pnas.1209018109. [PDB: 4eeb, 4eed] CMCF-ID Health
Purohit, Meena K.; Poduch, Ewa; Wei, Lianhu William; Crandall, Ian Edward; To, Terrence et al. (2012). Novel Cytidine-Based Orotidine-5′-Monophosphate Decarboxylase Inhibitors with an Unusual Twist. Journal of Medicinal Chemistry 55(22) , 9988-9997. 10.1021/jm301176r. [PDB: 4hib] CMCF-ID Health
Safaee, Nozhat; Kozlov, Guennadi; Noronha, Anne M.; Xie, Jingwei; Wilds, Christopher J. et al. (2012). Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G. Molecular Cell 48(3) , 375-386. 10.1016/j.molcel.2012.09.001. [PDB: 4f02] CMCF-ID Health
Shniffer, Adin; Visschedyk, Danielle D.; Ravulapalli, Ravikiran; Suarez, Giovanni; Turgeon, Zachari J. et al. (2012). Characterization of an Actin-targeting ADP-ribosyltransferase from Aeromonas hydrophila. Journal of Biological Chemistry 287(44) , 37030-37041. 10.1074/jbc.m112.397612. [PDB: 4fml] CMCF-ID Health