Publication Beamlines Strategic Pillar
Lewis, Steven M; Wu, Xiufeng; Pustilnik, Anna; Sereno, Arlene; Huang, Flora et al. (2014). Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nature Biotechnology 32(2) , 191-198. 10.1038/nbt.2797. [PDB: 4lld] CMCF-ID Health
Murase, Tomohiko; Eugenio, Luiz; Schorr, Melissa; Hussack, Greg; Tanha, Jamshid et al. (2014). Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. Journal of Biological Chemistry 289(4) , 2331-2343. 10.1074/jbc.m113.505917. [PDB: 4nbx, 4nby, 4nc1] CMCF-BM Health
Thi, Nhung Nguyen; Offen, Wendy A.; Shareck, François; Davies, Gideon J.; Doucet, Nicolas et al. (2014). Structure and Activity of the Streptomyces coelicolor A3(2) β-N-Acetylhexosaminidase Provides Further Insight into GH20 Family Catalysis and Inhibition. Biochemistry 53(11) , 1789-1800. 10.1021/bi401697j. [PDB: 4c7f] CMCF-ID Health
Keszei, Alexander F. A.; Tang, Xiaojing; McCormick, Craig; Zeqiraj, Elton; Rohde, John R. et al. (2014). Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase. Molecular and Cellular Biology 34(3) , 362-373. 10.1128/mcb.01360-13. [PDB: 4nkg] CMCF-ID Health
Kiefer, Susan E.; Chang, ChiehYing J.; Kimura, S. Roy; Gao, Mian; Xie, Dianlin et al. (2014). The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor. Acta Crystallographica Section F Structural Biology and Crystallization Communications 70(2) , 173-181. 10.1107/s2053230x14000144. [PDB: 4nfm] CMCF-ID Health
Yao, Deqiang; Cherney, Maia; Cygler, Miroslaw (2014). Structure of the N-terminal domain of the effector protein LegC3 fromLegionella pneumophila. Acta Crystallographica Section D Biological Crystallography 70(2) , 436-441. 10.1107/s139900471302991x. [PDB: 4mu6] CMCF-ID Health
Lee, Jaeyong; Taneva, Svetla G.; Holland, Bryan W.; Tieleman, D. Peter; Cornell, Rosemary B. et al. (2014). Structural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic Helix. Journal of Biological Chemistry 289(3) , 1742-1755. 10.1074/jbc.m113.526970. [PDB: 4mvc, 4mvd] CMCF-BM, CMCF-ID Health
Zheng, Xiaozhang; Baumeister, Timm; Buckmelter, Alexandre J.; Caligiuri, Maureen; Clodfelter, Karl H. et al. (2014). Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors. Bioorganic and Medicinal Chemistry Letters 24(1) , 337-343. 10.1016/j.bmcl.2013.11.006. [PDB: 4lww] CMCF-ID Health
Krska, Daniel (2014). Larvin: The characterization of a novel mono-ADP-ribosyltransferase toxin. Supervisor: Merrill, Rod. Ontario, Canada: The University of Guelph. http://hdl.handle.net/10214/8117. CMCF-ID Health
David E. Heinrichs; Federico Beasley; Enríque Vines; Johnson Cheung (2014). Siderophore-mediated iron uptake in bacterial infection. Patent Number: US8637657B2. CMCF-ID Health
Sheriff, S. (2014). Human tau tubulin kinase 1 (TTBK1). Protein Data Bank: 4nfm. CMCF-ID Health
Cygler, M.; Grishin, A.M.; Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) (2014). Bacterial Effector NleH2 Kinase Domain. Protein Data Bank: 4lrk. CMCF-ID Health
Cygler, M.; Grishin, A.M.; Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) (2014). Bacterial Effector NleH1 Kinase Domain with AMPPNP and Mg2+. Protein Data Bank: 4lrj. CMCF-ID Health
Pustilnik, A.; Lewis, S.M.; Wu, X.; Sereno, A.; Huang, F. et al. (2014). Structure of wild-type IgG1 antibody heavy chain constant domain 1 and light chain lambda constant domain (IgG1 CH1:Clambda) at 1.19A. Protein Data Bank: 4lld. CMCF-ID Health
Nguyen Thi, N.; Offen, W.A.; Davies, G.J.; Doucet, N. (2014). Structure and activity of the GH20 beta-N-acetylhexosaminidase from Streptomyces coelicolor A3(2). Protein Data Bank: 4c7f. CMCF-ID Health