Publication Beamlines Strategic Pillar
Fard, Z. H.; Kalinovskyy, Y.; Spasyuk, D. M.; Blight, B. A.; Shimizu, G. K. H. et al. (2016). Alkaline-earth phosphonate MOFs with reversible hydration-dependent fluorescence. Chemical Communications 52(87) , 12865-12868. 10.1039/c6cc06490f. CMCF-BM Materials
Grandin, Mélodie; Meier, Markus; Delcros, Jean Guy; Nikodemus, Denise; Reuten, Raphael et al. (2016). Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers. Cancer Cell 29(2) , 173-185. 10.1016/j.ccell.2016.01.001. [PDB: 4ove] CMCF-BM Health
Kobylarz, Marek J.; Grigg, Jason C.; Liu, Yunan; Lee, Mathew S. F.; Heinrichs, David E. et al. (2016). Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis. Biochemistry 55(6) , 927-939. 10.1021/acs.biochem.5b01045. [PDB: 5d84] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan (2016). Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. Journal of Biological Chemistry 291(12) , 6376-6385. 10.1074/jbc.m115.711085. [PDB: 5fc1, 5fc6, 5fc7, 5fca, 5fcb] CMCF-BM, CMCF-ID Health
Liu, Yanjie; Frirdich, Emilisa; Taylor, Jennifer A.; Chan, Anson C. K.; Blair, Kris M. et al. (2016). A Bacterial Cell Shape-Determining Inhibitor. ACS Chemical Biology 11(4) , 981-991. 10.1021/acschembio.5b01039. [PDB: 5d2r] CMCF-BM Health
Hamilton, Jordan G.; Farrell, Richard E.; Chen, Ning; Feng, Renfei; Reid, Joel et al. (2016). Characterizing Zinc Speciation in Soils from a Smelter-Affected Boreal Forest Ecosystem. Journal of Environmental Quality 45(2) , 684-692. 10.2134/jeq2015.03.0145. CMCF-BM, HXMA, VESPERS Environment
Bergeron, Julien R.C.; Fernández, Lucia; Wasney, Gregory A.; Vuckovic, Marija; Reffuveille, Fany et al. (2016). The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing. Journal of Biological Chemistry 291(4) , 1676-1691. 10.1074/jbc.m115.684423. [PDB: 5cuk, 5cul] CMCF-BM, CMCF-ID Health
Argyropoulos, Panos; Bergeret, Fabien; Pardin, Christophe; Reimer, Janice M.; Pinto, Atahualpa et al. (2016). Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis. Biochimica et Biophysica Acta - General Subjects 1860(3) , 486-497. 10.1016/j.bbagen.2015.11.007. [PDB: 5d3k] CMCF-BM Health
Hanan, Emily J.; Baumgardner, Matt; Bryan, Marian C.; Chen, Yuan; Eigenbrot, Charles et al. (2016). 4-Aminoindazolyl-dihydrofuro[3,4- d ]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase. Bioorganic and Medicinal Chemistry Letters 26(2) , 534-539. 10.1016/j.bmcl.2015.11.078. [PDB: 5edp, 5edq] CMCF-BM Health
Wu, Wen-Lian; Hao, Jinsong; Domalski, Martin; Burnett, Duane A.; Pissarnitski, Dmitri et al. (2016). Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 Diabetes. ACS Medicinal Chemistry Letters 7(5) , 498-501. 10.1021/acsmedchemlett.6b00027. [PDB: 5i7u] CMCF-ID Health
Shaw, Alice T.; Friboulet, Luc; Leshchiner, Ignaty; Gainor, Justin F.; Bergqvist, Simon et al. (2016). Resensitization to Crizotinib by the LorlatinibALKResistance Mutation L1198F. New England Journal of Medicine 374(1) , 54-61. 10.1056/nejmoa1508887. [PDB: 5a9u, 5aac] CMCF-ID Health
Taylor, Alexander M.; Côté, Alexandre; Hewitt, Michael C.; Pastor, Richard; Leblanc, Yves et al. (2016). Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637). ACS Medicinal Chemistry Letters 7(5) , 531-536. 10.1021/acsmedchemlett.6b00075. [PDB: 5i83, 5i86] CMCF-ID Health
Gruninger, Robert J.; Cote, Chris; McAllister, Tim A.; Abbott, D. Wade (2016). Contributions of a unique β-clamp to substrate recognition illuminates the molecular basis of exolysis in ferulic acid esterases. Biochemical Journal 473(7) , 839-849. 10.1042/bj20151153. [PDB: 5cxu, 5cxx] CMCF-ID Agriculture
Bloudoff, Kristjan; Alonzo, Diego A.; Schmeing, T. Martin (2016). Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases. Cell Chemical Biology 23(3) , 331-339. 10.1016/j.chembiol.2016.02.012. [PDB: 5du9, 5dua] CMCF-ID Health
Jha, Vikash; Bian, Chuanbing; Xing, Guangxin; Ling, Hong (2016). Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase κ. Nucleic Acids Research 44(10) , 4957-4967. 10.1093/nar/gkw204. [PDB: 4u6p, 4u7c] CMCF-ID Health