Publication Beamlines Strategic Pillar
Gobeil, Sophie M. C.; Ebert, Maximillian C. C. J. C.; Park, Jaeok; Gagné, Donald; Doucet, Nicolas et al. (2019). The Structural Dynamics of Engineered β-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function. Scientific Reports 9(1) . 10.1038/s41598-019-42866-8. [PDB: 4r4s] CMCF-ID Health
Velagapudi, Uday Kiran; Langelier, Marie-France; Delgado-Martin, Cristina; Diolaiti, Morgan E.; Bakker, Sietske et al. (2019). Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. Journal of Medicinal Chemistry 62(11) , 5330-5357. 10.1021/acs.jmedchem.8b01709. [PDB: 6nrf, 6nrg, 6nrh, 6nri, 6nrj] CMCF-ID Health
Sahtout, Naheda; Kuttiyatveetil, Jijin R.A.; Sanders, David A.R. (2019). Structure and function of the putative thioredoxin 1 from the thermophilic eubacterium Thermosipho africanus strain TCF52B. Biochimica et Biophysica Acta - Proteins and Proteomics 1867(4) , 426-433. 10.1016/j.bbapap.2019.01.011. [PDB: 6mos] CMCF-ID Health
Smith, Bryan D.; Kaufman, Michael D.; Lu, Wei-Ping; Gupta, Anu; Leary, Cynthia B. et al. (2019). Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants. Cancer Cell 35(5) , 738-751.e9. 10.1016/j.ccell.2019.04.006. [PDB: 6mob] CMCF-ID Health
Huang, Ji; Nguyen, Vinh H.; Hamblin, Karleigh A.; Maytum, Robin; van der Giezen, Mark et al. (2019). ATP-specificity of succinyl-CoA synthetase fromBlastocystis hominis. Acta Crystallographica Section D: Structural Biology 75(7) , 647-659. 10.1107/s2059798319007976. [PDB: 6no1, 6no2, 6no3, 6no4] CMCF-ID Health
Rahfeld, Peter; Sim, Lyann; Moon, Haisle; Constantinescu, Iren; Morgan-Lang, Connor et al. (2019). An enzymatic pathway in the human gut microbiome that converts A to universal O type blood. Nature Microbiology 4(9) . 10.1038/s41564-019-0469-7. [PDB: 6n1a] CMCF-ID Health
Kimber, M.S.; Mallette, E.; Aggett, R.; Seah, S.Y.K. (2019). Ltp2-ChsH2(DUF35) aldolase. Protein Data Bank: 6ok1. CMCF-BM Health
Newson, JoshuaP.M.; Scott, NichollasE.; Yeuk Wah Chung, Ivy; Wong Fok Lung, Tania; Giogha, Cristina et al. (2019). Salmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways*. Molecular and Cellular Proteomics 18(6) , 1138-1156. 10.1074/mcp.ra118.001093. [PDB: 6cgi, 6dus] CMCF-BM, CMCF-ID Health
Xu, C.; Boniecki, M.; Cygler, M. (2019). Structure of the N-terminal domain of effector protein SpvB from Salmonella typhimurium strain LT2. Protein Data Bank: 6p0x. CMCF-ID Health
Sim, L.; Rahfeld, P.; Withers, S.G. (2019). Crystal structure of an N-acetylgalactosamine deacetylase from F. plautii in complex with blood group B trisaccharide. Protein Data Bank: 6n1b. CMCF-ID Health
Sim, L.; Rahfeld, P.; Withers, S.G. (2019). Crystal structure of an N-acetylgalactosamine deacetylase from F. plautii. Protein Data Bank: 6n1a. CMCF-ID Health
Kolesnikov, M.; Murphy, M.E.P. (2019). Crystal structure of Fusobacterium nucleatum flavodoxin mutant K13G bound to flavin mononucleotide. Protein Data Bank: 6ohk. CMCF-ID Health
Mothersole, Robert G.; Macdonald, Marta; Kolesnikov, Maxim; Murphy, Michael E. P.; Wolthers, Kirsten R. et al. (2019). Structural insight into the high reduction potentials observed for Fusobacterium nucleatum flavodoxin. Protein Science 28(8) . 10.1002/pro.3661. [PDB: 6ohk] CMCF-BM Health
Shah, M.; Thavalingham, A.; Maxwell, K.L.; Moraes, T.F. (2019). Structure of anti-crispr protein, AcrIIC2. Protein Data Bank: 6n05. CMCF-BM Health
Yachnin, B.J.; Berghuis, A.M. (2019). Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor. Protein Data Bank: 6ny0. CMCF-ID Health