Publication Beamlines Strategic Pillar
Saran, S.; Majdi Yazdi, M.; Sanders, D.A.R. (2021). Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site and L-histidine bound at the allosteric site. Protein Data Bank: 7kg2. CMCF-ID Health
Murray, B.W.; Rogers, E.; Zhai, D.; Deng, W.; Chen, X. et al. (2021). Crystal structure of TrkA kinase with repotrectinib. Protein Data Bank: 7vko. CMCF-ID Health
Ereno-Orbea, J.; Nilvebrant, J.; Sidhu, S.; Julien, J.P. (2021). Anti-EphA1 JD1 VH domain. Protein Data Bank: 7ooi. CMCF-ID Health
Nilvebrant, Johan; EreƱo-Orbea, June; Gorelik, Maryna; Julian, Mark C.; Tessier, Peter M. et al. (2021). Systematic Engineering of Optimized Autonomous Heavy-Chain Variable Domains. Journal of Molecular Biology 433(21) , 167241. 10.1016/j.jmb.2021.167241. [PDB: 7ooi] CMCF-ID Health
Saran, S.; Sanders, D.A.R. (2021). Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site. Protein Data Bank: 7kel. CMCF-ID Health
Sahtout, N.; Kuttiyatveetil, J.R.A.; Sanders, D.A.R. (2021). Structure of thioredoxin reductase from the thermophilic eubacterium Thermosipho africanus TCF52B. Protein Data Bank: 7jyp. CMCF-ID Health
Kalthoff, E.; Schmeing, M. (2021). Crystal structure of the M. abscessus LeuRS editing domain in complex with epetraborole-AMP adduct. Protein Data Bank: 7n12. CMCF-BM Health
Hill, Matthew D.; Quesnelle, Claude; Tokarski, John; Fang, Haiquan; Fanslau, Carolynn et al. (2021). Development of BET inhibitors as potential treatments for cancer: A new carboline chemotype. Bioorganic and Medicinal Chemistry Letters 51, 128376. 10.1016/j.bmcl.2021.128376. [PDB: 7mce] CMCF-ID Health
Liu, Weifeng; Maben, Zachary; Wang, Carole; Lindquist, Kevin C.; Li, Manqing et al. (2021). Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex. Journal of Biological Chemistry 297(4) , 101102. 10.1016/j.jbc.2021.101102. [PDB: 7kx0] CMCF-ID Health
Vuong, Wayne; Fischer, Conrad; Khan, Muhammad Bashir; van Belkum, Marco J.; Lamer, Tess et al. (2021). Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies. European Journal of Medicinal Chemistry 222, 113584. 10.1016/j.ejmech.2021.113584. [PDB: 7lco, 7ldl] CMCF-BM Health