Publication Beamlines Strategic Pillar
Awad, Mark M.; Katayama, Ryohei; McTigue, Michele; Liu, Wei; Deng, Ya-Li et al. (2013). Acquired Resistance to Crizotinib from a Mutation in CD74–ROS1. New England Journal of Medicine 368(25) , 2395-2401. 10.1056/nejmoa1215530. [PDB: 3zbf] CMCF-ID
Barrette-Ng, Isabelle H.; Wu, Sau-Ching; Tjia, Wai-Mui; Wong, Sui-Lam; Ng, Kenneth K. S. et al. (2013). The structure of the SBP-Tag–streptavidin complex reveals a novel helical scaffold bridging binding pockets on separate subunits. Acta Crystallographica Section D Biological Crystallography 69(5) , 879-887. 10.1107/s0907444913002576. CMCF-ID
Bergeron, Julien R. C.; Worrall, Liam J.; Sgourakis, Nikolaos G.; DiMaio, Frank; Pfuetzner, Richard A. et al. (2013). A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly. PLoS Pathogens 9(4) , e1003307. 10.1371/journal.ppat.1003307. [PDB: 4g08, 4g1i, 4g2s] CMCF-ID
Carere, Jason; McKenna, Sarah E.; Kimber, Matthew S.; Seah, Stephen Y. K. (2013). Characterization of an Aldolase–Dehydrogenase Complex from the Cholesterol Degradation Pathway of Mycobacterium tuberculosis. Biochemistry 52(20) , 3502-3511. 10.1021/bi400351h. [PDB: 4jn6] CMCF-ID
Gonzalez-Lopez de Turiso, Felix; Sun, Daqing; Rew, Yosup; Bartberger, Michael D.; Beck, Hilary P. et al. (2013). Rational Design and Binding Mode Duality of MDM2–p53 Inhibitors. Journal of Medicinal Chemistry 56(10) , 4053-4070. 10.1021/jm400293z. [PDB: 4jwr] CMCF-ID
Guo, Chuangxing; Linton, Angelica; Jalaie, Mehran; Kephart, Susan; Ornelas, Martha et al. (2013). Discovery of 2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as novel PKM2 activators. Bioorganic and Medicinal Chemistry Letters 23(11) , 3358-3363. 10.1016/j.bmcl.2013.03.090. [PDB: 4jpg] CMCF-ID
Lazareno-Saez, Christelle; Arutyunova, Elena; Coquelle, Nicolas; Lemieux, M. Joanne (2013). Domain Swapping in the Cytoplasmic Domain of the Escherichia coli Rhomboid Protease. Journal of Molecular Biology 425(7) , 1127-1142. 10.1016/j.jmb.2013.01.019. [PDB: 4hdd] CMCF-ID
Maynard, Andrew; Crosby, Renae M.; Ellis, Byron; Hamatake, Robert; Hong, Zhi et al. (2013). Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase. Journal of Medicinal Chemistry 57(5) , 1902-1913. 10.1021/jm400317w. [PDB: 4khr] CMCF-ID
Pantua, Homer; Diao, Jingyu; Ultsch, Mark; Hazen, Meredith; Mathieu, Mary et al. (2013). Glycan Shifting on Hepatitis C Virus (HCV) E2 Glycoprotein Is a Mechanism for Escape from Broadly Neutralizing Antibodies. Journal of Molecular Biology 425(11) , 1899-1914. 10.1016/j.jmb.2013.02.025. [PDB: 4hs6] CMCF-ID
Safaee, Nozhat; Noronha, Anne M.; Rodionov, Dmitry; Kozlov, Guennadi; Wilds, Christopher J. et al. (2013). Structure of the Parallel Duplex of Poly(A) RNA: Evaluation of a 50 Year-Old Prediction. Angewandte Chemie - International Edition 52(39) , 10370-10373. 10.1002/anie.201303461. [PDB: 4jrd] CMCF-ID
Schellenberg, Matthew J; Wu, Tao; Ritchie, Dustin B; Fica, Sebastian; Staley, Jonathan P et al. (2013). A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nature Structural and Molecular Biology 20(6) , 728-734. 10.1038/nsmb.2556. [PDB: 4jk7, 4jk8, 4jk9, 4jka, 4jkb, 4jkc, 4jkh] CMCF-ID
Solomonson, Matthew; Huesgen, Pitter F.; Wasney, Gregory A.; Watanabe, Nobuhiko; Gruninger, Robert J. et al. (2013). Structure of the Mycosin-1 Protease from the Mycobacterial ESX-1 Protein Type VII Secretion System. Journal of Biological Chemistry 288(24) , 17782-17790. 10.1074/jbc.m113.462036. [PDB: 4j94, 4kpg] CMCF-BM
Sweeting, Braden; Brown, Eric; Khan, M. Qasim; Chakrabartty, Avijit; Pai, Emil F. et al. (2013). N-Terminal Helix-Cap in α-Helix 2 Modulates β-State Misfolding in Rabbit and Hamster Prion Proteins. PLoS ONE 8(5) , e63047. 10.1371/journal.pone.0063047. [PDB: 4hls, 4hmm, 4hmr] CMCF-ID
Trempe, J.-F.; Sauve, V.; Grenier, K.; Seirafi, M.; Tang, M. Y. et al. (2013). Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation. Science 340(6139) , 1451-1455. 10.1126/science.1237908. [PDB: 4k7d] CMCF-ID
Vinaik, Roohi; Kozlov, Guennadi; Gehring, Kalle (2013). Structure of the Non-Catalytic Domain of the Protein Disulfide Isomerase-Related Protein (PDIR) Reveals Function in Protein Binding. PLoS ONE 8(4) , e62021. 10.1371/journal.pone.0062021. CMCF-ID