Publication Beamlines Strategic Pillar
Deaton, David N.; Diaz, Elsie; Do, Young; Gampe, Robert T.; Guss, Jeffrey H. et al. (2021). A knowledge-based, structural-aided discovery of a novel class of 2-phenylimidazo[1,2-a]pyridine-6-carboxamide H-PGDS inhibitors. Bioorganic and Medicinal Chemistry Letters , 128113. 10.1016/j.bmcl.2021.128113. [PDB: 7jr6] CMCF-ID
Golkar, Tolou; Bassenden, Angelia V.; Maiti, Krishnagopal; Arya, Dev P.; Schmeing, T. Martin et al. (2021). Structural basis for plazomicin antibiotic action and resistance. Communications Biology 4(1) . 10.1038/s42003-021-02261-4. [PDB: 6vou, 7lh5] CMCF-ID Health
Guo, Shuaiqi; Vance, Tyler D. R.; Zahiri, Hossein; Eves, Robert; Stevens, Corey et al. (2021). Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation. mBio 12(2) . 10.1128/mbio.00130-21. [PDB: 6x7j, 6x7t, 6x7y, 6x7z, 6x8a, 6x8d, 6x8y, 6x95, 6x9m, 6x9p, 6xa5, 6xaq] CMCF-ID Health
Hu, Carol H.; Neissel Valente, Meriah W.; Scott Halpern, O.; Jusuf, Sutjano; Khan, Javed A. et al. (2021). Small Molecule and Macrocyclic Pyrazole Derived Inhibitors of Myeloperoxidase (MPO). Bioorganic and Medicinal Chemistry Letters , 128010. 10.1016/j.bmcl.2021.128010. [PDB: 7lag, 7lan] CMCF-ID
Li, Franco K.K.; Gale, Robert T.; Petrotchenko, Evgeniy V.; Borchers, Christoph H.; Brown, Eric D. et al. (2021). Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis. Journal of Structural Biology 213(2) , 107733. 10.1016/j.jsb.2021.107733. [PDB: 6xh9, 6xhk, 6xhp, 6xhq, 6xhr, 6xhs, 6xht] CMCF-ID
Prasertanan, Theerawat; Palmer, David R.J.; Sanders, David A.R. (2021). Snapshots along the catalytic path of KabA, a PLP-dependent aminotransferase required for kanosamine biosynthesis in Bacillus cereus UW85. Journal of Structural Biology 213(2) , 107744. 10.1016/j.jsb.2021.107744. [PDB: 7kz3, 7kz5, 7kz6, 7kzd] CMCF-ID
Vuong, Wayne; Fischer, Conrad; Khan, Muhammad Bashir; van Belkum, Marco J.; Lamer, Tess et al. (2021). Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: structural enhancements, increased solubility, and micellar studies. European Journal of Medicinal Chemistry , 113584. 10.1016/j.ejmech.2021.113584. CMCF-BM Health
Wigle, Tim; Ren, Yue; Molina, Jennifer R.; Blackwell, Danielle J.; Schenkel, Laurie B. et al. (2021). Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule. ChemBioChem . 10.1002/cbic.202100047. [PDB: 7l9y] CMCF-ID
Scire, Michelle Denise (2021). Structure and Function of MUC1 Specific Monoclonal Antibodies. Supervisor: Brooks, Cory L.. California, United States: California State University, Fresno. CMCF-ID
Bassenden, A.V.; Berghuis, A.M. (2021). Aminoglycoside N-2'-Acetyltransferase-Ia [AAC(2')-Ia] in complex with acetylated-plazomicin and CoA. Protein Data Bank: 6vou. CMCF-ID Health
Chen, Y.S.; Kozlov, G.; Gehring, K. (2021). Crystal structure of an archaeal CNNM, MtCorB, with C-terminal deletion in complex with Mg2+-ATP. Protein Data Bank: 7m1t. CMCF-ID Agriculture
Chen, Y.S.; Kozlov, G.; Gehring, K. (2021). Crystal structure of an archaeal CNNM, MtCorB, R235L mutant with C-terminal deletion. Protein Data Bank: 7m1u. CMCF-BM Agriculture
Dorsey, B.W.; Swinger, K.K.; Schenkel, L.B.; Church, W.D.; Perl, N.R. et al. (2021). Human PARP14 (ARTD8), catalytic fragment in complex with RBN012042. Protein Data Bank: 7l9y. CMCF-ID
Golkar, T.; Berghuis, A.M.; Schmeing, T.M. (2021). Crystal structure of the Thermus thermophilus 70S ribosome in complex with plazomicin, mRNA and tRNAs. Protein Data Bank: 7lh5. CMCF-ID Health
Guo, S.; Davies, P.L. (2021). fucose-bound structure of Marinomonas primoryensis PA14 carbohydrate-binding domain. Protein Data Bank: 6x7j. CMCF-ID Health