Publication Beamlines Strategic Pillar
Bateman, Thomas J.; Shah, Megha; Ho, Timothy Pham; Shin, Hyejin Esther; Pan, Chuxi et al. (2021). A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii. Nature Communications 12(1) . 10.1038/s41467-021-26545-9. [PDB: 7re4, 7rea, 7red] CMCF-BM, CMCF-ID Health
Boddington, Kelly F.; Soubeyrand, Eric; Van Gelder, Kristen; Casaretto, José A.; Perrin, Colby et al. (2021). Bibenzyl synthesis in Cannabis sativa L.. Plant Journal . 10.1111/tpj.15588. [PDB: 7sgy] CMCF-ID Agriculture
Casimiro-Garcia, Agustin; Allais, Christophe; Brennan, Agnes; Choi, Chulho; Dower, Gabriela et al. (2021). Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin-1. Journal of Medicinal Chemistry 65(1) , 757-784. 10.1021/acs.jmedchem.1c01849. [PDB: 7sly] CMCF-ID Health
Chung, Ivy Yeuk Wah; Li, Lei; Cygler, Miroslaw (2021). Legionella effector LegA15/AnkH contains an unrecognized cysteine protease-like domain and displays structural similarity to LegA3/AnkD, but differs in host cell localization. Acta Crystallographica Section D: Structural Biology 77(12) . 10.1107/s2059798321010469. [PDB: 7kj6] CMCF-BM Health
Hill, Matthew D.; Quesnelle, Claude; Tokarski, John; Fang, Haiquan; Fanslau, Carolynn et al. (2021). Development of BET inhibitors as potential treatments for cancer: A new carboline chemotype. Bioorganic and Medicinal Chemistry Letters 51, 128376. 10.1016/j.bmcl.2021.128376. [PDB: 7mce] CMCF-ID Health
Keylor, Mitchell H.; Gulati, Anmol; Kattar, Solomon D.; Johnson, Rebecca E.; Chau, Ryan W. et al. (2021). Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors. Journal of Medicinal Chemistry 65(1) , 838-856. 10.1021/acs.jmedchem.1c01968. [PDB: 7suh] CMCF-ID Health
Liu, Weifeng; Maben, Zachary; Wang, Carole; Lindquist, Kevin C.; Li, Manqing et al. (2021). Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex. Journal of Biological Chemistry 297(4) , 101102. 10.1016/j.jbc.2021.101102. [PDB: 7kx0] CMCF-ID Health
Nasu, Yusuke; Murphy-Royal, Ciaran; Wen, Yurong; Haidey, Jordan N.; Molina, Rosana S. et al. (2021). A genetically encoded fluorescent biosensor for extracellular l-lactate. Nature Communications 12(1) . 10.1038/s41467-021-27332-2. [PDB: 7e9y] CMCF-ID Health
Nilvebrant, Johan; Ereño-Orbea, June; Gorelik, Maryna; Julian, Mark C.; Tessier, Peter M. et al. (2021). Systematic Engineering of Optimized Autonomous Heavy-Chain Variable Domains. Journal of Molecular Biology 433(21) , 167241. 10.1016/j.jmb.2021.167241. [PDB: 7ooi] CMCF-ID Health
Pham, N. T. Hang; Létourneau, Myriam; Fortier, Marlène; Bégin, Gabriel; Al-Abdul-Wahid, M. Sameer et al. (2021). Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7. Journal of Biological Chemistry 297(5) , 101308. 10.1016/j.jbc.2021.101308. [PDB: 6vtp, 6vtr] CMCF-BM Health
Stille, Julia K.; Tjutrins, Jevgenijs; Wang, Guanyu; Venegas, Felipe A.; Hennecker, Christopher et al. (2021). Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CLpro covalent inhibitors. European Journal of Medicinal Chemistry , 114046. 10.1016/j.ejmech.2021.114046. [PDB: 7mlf] CMCF-BM Health
Vuong, Wayne; Fischer, Conrad; Khan, Muhammad Bashir; van Belkum, Marco J.; Lamer, Tess et al. (2021). Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies. European Journal of Medicinal Chemistry 222, 113584. 10.1016/j.ejmech.2021.113584. [PDB: 7lco, 7ldl] CMCF-BM Health
Bateman, T.J.; Shah, M.; Moraes, T.F. (2021). Holo Hemophilin from A. baumannii. Protein Data Bank: 7red. CMCF-ID Health
Bateman, T.J.; Shah, M.; Moraes, T.F. (2021). Apo Hemophilin from A. baumannii. Protein Data Bank: 7rea. CMCF-BM Health
Bateman, T.J.; Shah, M.; Moraes, T.F. (2021). Apo Hemophilin from A. baumannii. Protein Data Bank: 7re4. CMCF-BM Health