Publication Beamlines Strategic Pillar
Forrester, Taylor J. B.; Ovchinnikova, Olga G.; Li, Zhixiong; Kitova, Elena N.; Nothof, Jeremy T. et al. (2022). The retaining β-Kdo glycosyltransferase WbbB uses a double-displacement mechanism with an intermediate adduct rearrangement step. Nature Communications 13(1) . 10.1038/s41467-022-33988-1. [PDB: 8csb, 8csc, 8csd, 8cse, 8csf] CMCF-BM, CMCF-ID Health
Gheorghita, Andreea A.; Li, Yancheng E.; Kitova, Elena N.; Bui, Duong T.; Pfoh, Roland et al. (2022). Structure of the AlgKX modification and secretion complex required for alginate production and biofilm attachment in Pseudomonas aeruginosa. Nature Communications 13(1) . 10.1038/s41467-022-35131-6. [PDB: 7ula] CMCF-BM Health
Gorelik, Alexei; Illes, Katalin; Bui, Khanh Huy; Nagar, Bhushan (2022). Structures of the mannose-6-phosphate pathway enzyme, GlcNAc-1-phosphotransferase. Proceedings of the National Academy of Sciences of the United States of America 119(33) . 10.1073/pnas.2203518119. CMCF-BM Health
Kuttiyatveetil, Jijin R.A.; Soufari, Heddy; Dasovich, Morgan; Uribe, Isabel R.; Mirhasan, Manija et al. (2022). Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a distinctive mode of engaging poly(ADP-ribose). Cell Reports 41(4) , 111529. 10.1016/j.celrep.2022.111529. [PDB: 7sz2, 7sz3] CMCF-BM Health
Lee, Jaeyong; Kenward, Calem; Worrall, Liam J.; Vuckovic, Marija; Gentile, Francesco et al. (2022). X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nature Communications 13(1) . 10.1038/s41467-022-32854-4. [PDB: 8dru, 8drx, 8ds1] CMCF-BM Health
Li, Mingzong; Konteatis, Zenon; Nagaraja, Nelamangala; Chen, Yue; Zhou, Shubao et al. (2022). Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. Journal of Medicinal Chemistry 65(6) , 4600-4615. 10.1021/acs.jmedchem.1c01595. [PDB: 7rwg] CMCF-BM Health
Lorente Cobo, Neil; Sibinelli-Sousa, Stephanie; Biboy, Jacob; Vollmer, Waldemar; Bayer-Santos, Ethel et al. (2022). Molecular characterization of the type VI secretion system effector Tlde1a reveals a structurally altered LD-transpeptidase fold. Journal of Biological Chemistry 298(11) , 102556. 10.1016/j.jbc.2022.102556. [PDB: 7uo3, 7uo8] CMCF-BM Health
Lu, Jimmy; Chen, Sizhu Amelia; Khan, Muhammad Bashir; Brassard, Raelynn; Arutyunova, Elena et al. (2022). Crystallization of Feline Coronavirus Mpro With GC376 Reveals Mechanism of Inhibition. Frontiers in Chemistry 10. 10.3389/fchem.2022.852210. [PDB: 7smv, 7sna] CMCF-BM Health
Mabanglo, Mark F.; Wong, Keith S.; Barghash, Marim M.; Leung, Elisa; Chuang, Stephanie H.W. et al. (2022). Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome. Structure . 10.1016/j.str.2022.12.002. [PDB: 7uvm, 7uvn, 7uvr, 7uvu, 7uw0] CMCF-BM Health
Mothersole, Robert G.; Kolesnikov, Maxim; Chan, Anson C. K.; Oduro, Emmanuella; Murphy, Michael E. P. et al. (2022). Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species. Biochemistry 61(13) , 1378-1391. 10.1021/acs.biochem.2c00197. [PDB: 8d27] CMCF-BM Health
Navas, Laura E.; Zahn, Michael; Bajwa, Harbir; Grigg, Jason C.; Wolf, Megan E. et al. (2022). Characterization of a phylogenetically distinct extradiol dioxygenase involved in the bacterial catabolism of lignin-derived aromatic compounds. Journal of Biological Chemistry 298(5) , 101871. 10.1016/j.jbc.2022.101871. [PDB: 7q2a] CMCF-BM Health
Nguyen, Peter; Eshaque, Rony; Garland, Barbara Anne; Dang, Anthony; Suits, Michael D. L. et al. (2022). Degradation of chondroitin sulfate A by a PUL-like operon in Tannerella forsythia. PLoS ONE 17(9) , e0272904. 10.1371/journal.pone.0272904. [PDB: 8di0, 8di1] CMCF-BM, CMCF-ID Health
Niu, Xun; Foster, E. Johan; Patrick, Brian O.; Rojas, Orlando J. (2022). Betulin Self‐Assembly: From High Axial Aspect Crystals to Hedgehog Suprastructures. Advanced Functional Materials 32(44) , 2206058. 10.1002/adfm.202206058. CMCF-BM Materials
Parigi, Roberta; Pakostova, Eva; Reid, Joel W.; Saurette, Emily M.; McBeth, Joyce M. et al. (2022). Nickel Isotope Fractionation As an Indicator of Ni Sulfide Precipitation Associated with Microbially Mediated Sulfate Reduction. Environmental Science & Technology 56(12) , 7954-7962. 10.1021/acs.est.2c00523. CMCF-BM Environment
Pollock, Georgina L.; Grishin, Andrey M.; Giogha, Cristina; Gan, Jiyao; Oates, Clare V. et al. (2022). Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli. Proceedings of the National Academy of Sciences of the United States of America 119(34) . 10.1073/pnas.2204332119. [PDB: 7tzk] CMCF-BM Health