Publication Beamlines Strategic Pillar
Hersch, Steven J.; Watanabe, Nobuhiko; Stietz, Maria Silvina; Manera, Kevin; Kamal, Fatima et al. (2020). Envelope stress responses defend against type six secretion system attacks independently of immunity proteins. Nature Microbiology 5(5) . 10.1038/s41564-020-0672-6. [PDB: 6v98] CMCF-BM Health
Holt, Christian; Hamborg, Louise; Lau, Kelvin; Brohus, Malene; Sørensen, Anders Bundgaard et al. (2020). The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor. Journal of Biological Chemistry 295(22) , jbc.RA120.013430. 10.1074/jbc.ra120.013430. [PDB: 6y4p] CMCF-BM Health
Jones, Carys S.; Sychantha, David; Howell, P. Lynne; Clarke, Anthony J. (2020). Structural basis for the O-acetyltransferase function of the extracytoplasmic domain of OatA from Staphylococcus aureus. Journal of Biological Chemistry 295(24) , jbc.RA120.013108. 10.1074/jbc.ra120.013108. [PDB: 6wn9] CMCF-BM Health
Majdi Yazdi, Mohadeseh; Saran, Sagar; Mrozowich, Tyler; Lehnert, Cheyanne; Patel, Trushar R. et al. (2020). Asparagine-84, a regulatory allosteric site residue, helps maintain the quaternary structure of Campylobacter jejuni dihydrodipicolinate synthase. Journal of Structural Biology 209(1) . 10.1016/j.jsb.2019.107409. [PDB: 6tzu, 6u01] CMCF-BM, CMCF-ID Health
Miersch, Shane; Li, Zhijie; Saberianfar, Reza; Ustav, Mart; Case, James Brett et al. (2020). Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations. Vibrational Spectroscopy . 10.1101/2020.10.31.362848. [PDB: 7klg, 7klh] CMCF-BM Health
Miron, Caitlin E.; Staalduinen, Laura; Rangaswamy, Alana M.; Chen, Mickey; Liang, Yushi et al. (2020). Going Platinum to the Tune of a Remarkable Guanine Quadruplex Binder: Solution‐ and Solid‐State Investigations.. Angewandte Chemie - International Edition 60(5) . 10.1002/anie.202012520. [PDB: 6xcl] CMCF-BM Health
Pluvinage, Benjamin; Robb, Craig S.; Jeffries, Roderick; Boraston, Alisdair B. (2020). The structure of PfGH50B, an agarase from the marine bacterium Pseudoalteromonas fuliginea PS47. Acta Crystallographica Section F:Structural Biology Communications 76(9) , 422-427. 10.1107/s2053230x20010328. [PDB: 6xj9] CMCF-BM Health
Sokaribo, Akosiererem; Novakovski, Brian A.A.; Cotelesage, Julien; White, Aaron P.; Sanders, David et al. (2020). Kinetic and structural analysis of Escherichia coli phosphoenolpyruvate carboxykinase mutants. Biochimica et Biophysica Acta - General Subjects 1864(4) , 129517. 10.1016/j.bbagen.2020.129517. [PDB: 6v2l, 6v2m, 6v2n] CMCF-BM, CMCF-ID Health
Aggett, Rebecca; Mallette, Evan; Gilbert, Stephanie E.; Vachon, Melody A.; Schroeter, Kurt L. et al. (2019). The steroid side-chain–cleaving aldolase Ltp2–ChsH2DUF35 is a thiolase superfamily member with a radically repurposed active site. Journal of Biological Chemistry 294(31) , jbc.RA119.008889. 10.1074/jbc.ra119.008889. [PDB: 6ok1] CMCF-BM Health
Almawi, Ahmad W; Scotland, Michelle K; Randall, Justin R; Liu, Linda; Martin, Heather K et al. (2019). Binding of the regulatory domain of MutL to the sliding β-clamp is species specific. Nucleic Acids Research 47(9) . 10.1093/nar/gkz115. [PDB: 6e8d, 6e8e] CMCF-BM, CMCF-ID Health
Bamford, Natalie C.; Le Mauff, François; Subramanian, Adithya S.; Yip, Patrick; Millán, Claudia et al. (2019). Ega3 from the fungal pathogen Aspergillus fumigatus is an endo-α-1,4-galactosaminidase that disrupts microbial biofilms. Journal of Biological Chemistry 294(37) , 13833-13849. 10.1074/jbc.ra119.009910. [PDB: 6oj1] CMCF-BM Health
Caveney, Nathanael A.; Caballero, Guillermo; Voedts, Henri; Niciforovic, Ana; Worrall, Liam J. et al. (2019). Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nature Communications 10(1) . 10.1038/s41467-019-09507-0. [PDB: 6ntz] CMCF-BM, CMCF-ID Health
Caveney, Nathanael A.; Pavlin, Anja; Caballero, Guillermo; Bahun, Miha; Hodnik, Vesna et al. (2019). Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor. Structure 27(7) . 10.1016/j.str.2019.03.019. [PDB: 6n7o] CMCF-BM, CMCF-ID Health
Doyle, Liam; Ovchinnikova, Olga G.; Myler, Katharine; Mallette, Evan; Huang, Bo-Shun et al. (2019). Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules. Nature Chemical Biology 15(6) . 10.1038/s41589-019-0276-8. [PDB: 6mgb, 6mgc, 6mgd] CMCF-BM, CMCF-ID Health
Feng, Yuting; Park, Jaeok; Li, Shi-Guang; Boutin, Rebecca; Viereck, Peter et al. (2019). Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). Journal of Medicinal Chemistry 62(21) , 9691-9702. 10.1021/acs.jmedchem.9b01104. [PDB: 6n7y, 6n82, 6n83, 6oag, 6oah] CMCF-BM, CMCF-ID Health