Beshore, Douglas C.; Adam, Gregory C.; Barnard, Richard J. O.; Burlein, Christine; Gallicchio, Steven N. et al. (2021). Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction. ACS Medicinal Chemistry Letters 12(4) , 540-547. 10.1021/acsmedchemlett.1c00074. [PDB: 7ltg] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Burke, J.E.; Rathinaswamy, M.K.; Harris, N.J. (2021). Gedatolisib bound to the PI3Kg catalytic subunit p110 gamma. Protein Data Bank: 7jwe. |
CMCF-ID |
PDB Deposition |
Health |
Burke, J.E.; Rathinaswamy, M.K.; Harris, N.J. (2021). NVS-PI3-4 bound to the PI3Kg catalytic subunit p110 gamma. Protein Data Bank: 7jx0. |
CMCF-ID |
PDB Deposition |
Health |
Burke, J.E.; Rathinaswamy, M.K.; Harris, N.J. (2021). IPI-549 bound to the PI3Kg catalytic subunit p110 gamma. Protein Data Bank: 7jwz. |
CMCF-ID |
PDB Deposition |
Health |
Chen, Shuo; Wu, Jia-Le; Liang, Ying; Tang, Yi-Gang; Song, Hua-Xin et al. (2021). Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site. Cancer Cell 39(2) . 10.1016/j.ccell.2020.11.013. [PDB: 7dhz] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Chen, S.; Lu, M. (2021). Arsenic-bound p53 DNA-binding domain mutant R249S. Protein Data Bank: 7dhz. |
CMCF-ID |
PDB Deposition |
Health |
Chen; Y.S.; Kozlov; G.; Gehring et al. (2021). Crystal structure of MtCNNM with C-terminal deletion in complex with Mg2+-ATP. Protein Data Bank: 7lj7. |
CMCF-ID |
PDB Deposition |
Agriculture |
Chung, Ivy Y. W.; Li, Lei; Tyurin, Oleg; Gagarinova, Alla; Wibawa, Raissa et al. (2021). Structural and functional study of
Legionella pneumophila
effector RavA. Protein Science 30(5) . 10.1002/pro.4057. [PDB: 6wo6] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Cygler, M.; Chung, I.Y.W. (2021). Structure of RavA (lpp0008) E38A/K39A surface entropy reduction mutant. Protein Data Bank: 6wo6. |
CMCF-ID |
PDB Deposition |
Health |
Davies, Christopher W.; Stowe, Irma; Phung, Qui T.; Ho, Hoangdung; Bakalarski, Corey E. et al. (2021). Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function. Proceedings of the National Academy of Sciences of the United States of America 118(12) , e2018024118. 10.1073/pnas.2018024118. [PDB: 7jwq] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Dragovich, Peter S.; Pillow, Thomas H.; Blake, Robert A.; Sadowsky, Jack D.; Adaligil, Emel et al. (2021). Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy. Journal of Medicinal Chemistry 64(5) . 10.1021/acs.jmedchem.0c01846. [PDB: 7khl] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Heney, K.; Lyons, B.; Merrill, A.R. (2021). Scabin (Y129H) toxin from Streptomyces scabies. Protein Data Bank: 6vvf. |
CMCF-ID |
PDB Deposition |
Health |
Heney, K.; Lyons, B.; Merrill, A.R. (2021). Scabin (V109G) toxin from Streptomyces scabies. Protein Data Bank: 6vv4. |
CMCF-ID |
PDB Deposition |
Health |
Higgins, Melanie A.; Tegl, Gregor; MacDonald, Spencer S.; Arnal, Gregory; Brumer, Harry et al. (2021). N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes. ACS Chemical Biology 16(4) . 10.1021/acschembio.0c00995. [PDB: 7lqx, 7lr1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Huang, J.; Fraser, M.E. (2021). GTP-specific succinyl-CoA synthetase complexed with Mg-GMPPNP, phosphohistidine loop pointing towards nucleotide binding site. Protein Data Bank: 7jkr. |
CMCF-ID |
PDB Deposition |
Agriculture |