Publication Beamlines Strategic Pillar
Chong, Pek; Sebahar, Paul; Youngman, Michael; Garrido, Dulce; Zhang, Huichang et al. (2012). Rational Design of Potent Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase. Journal of Medicinal Chemistry 55(23) , 10601-10609. 10.1021/jm301294g. [PDB: 2yni] CMCF-ID Health
Zheng, Xiaozhang; Bair, Kenneth W.; Bauer, Paul; Baumeister, Timm; Bowman, Krista K. et al. (2013). Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorganic and Medicinal Chemistry Letters 23(20) , 5488-5497. 10.1016/j.bmcl.2013.08.074. [PDB: 4lva] CMCF-ID Health
Norman, Mark H.; Andrews, Kristin L.; Bo, Yunxin Y.; Booker, Shon K.; Caenepeel, Sean et al. (2012). Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511. Journal of Medicinal Chemistry 55(17) , 7796-7816. 10.1021/jm300846z. [PDB: 4flh] CMCF-ID Health
Bains, Jasleen; Leon, Rafael; Temke, Kevin G.; Boulanger, Martin J. (2011). Elucidating the reaction mechanism of the benzoate oxidation pathway encoded aldehyde dehydrogenase fromBurkholderia xenovoransLB400. Protein Science 20(6) , 1048-1059. 10.1002/pro.639. [PDB: 2y51, 2y52, 2y53, 2y5d] CMCF-ID Health
Yao, Deqiang; Cherney, Maia; Cygler, Miroslaw (2014). Structure of the N-terminal domain of the effector protein LegC3 fromLegionella pneumophila. Acta Crystallographica Section D Biological Crystallography 70(2) , 436-441. 10.1107/s139900471302991x. [PDB: 4mu6] CMCF-ID Health
Shi, Kun; Houston, Douglas R.; Berghuis, Albert M. (2011). Crystal Structures of Antibiotic-Bound Complexes of Aminoglycoside 2′′-Phosphotransferase IVa Highlight the Diversity in Substrate Binding Modes among Aminoglycoside Kinases. Biochemistry 50(28) , 6237-6244. 10.1021/bi200747f. [PDB: 3sg8] CMCF-ID Health
Chung, Ivy Yeuk Wah; Paetzel, Mark (2011). Crystal Structure of a Viral Protease Intramolecular Acyl-enzyme Complex. Journal of Biological Chemistry 286(14) , 12475-12482. 10.1074/jbc.m110.198812. [PDB: 3p06] CMCF-ID Health
Purohit, Meena K.; Poduch, Ewa; Wei, Lianhu William; Crandall, Ian Edward; To, Terrence et al. (2012). Novel Cytidine-Based Orotidine-5′-Monophosphate Decarboxylase Inhibitors with an Unusual Twist. Journal of Medicinal Chemistry 55(22) , 9988-9997. 10.1021/jm301176r. [PDB: 4hib] CMCF-ID Health
Grishin, Andrey M.; Ajamian, Eunice; Zhang, Linhua; Rouiller, Isabelle; Bostina, Mihnea et al. (2012). Protein-Protein Interactions in the β-Oxidation Part of the Phenylacetate Utilization Pathway. Journal of Biological Chemistry 287(45) , 37986-37996. 10.1074/jbc.m112.388231. [PDB: 4fzw] CMCF-ID Health
Turgeon, Zachari; Jørgensen, René; Visschedyk, Danielle; Edwards, Patrick R.; Legree, Sarah et al. (2011). Newly Discovered and Characterized Antivirulence Compounds Inhibit Bacterial Mono-ADP-Ribosyltransferase Toxins. Antimicrobial Agents and Chemotherapy 55(3) , 983-991. 10.1128/aac.01164-10. CMCF-ID Health
Kanjee, Usheer; Gutsche, Irina; Alexopoulos, Eftichia; Zhao, Boyu; El Bakkouri, Majida et al. (2011). Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase. EMBO Journal 30(5) , 931-944. 10.1038/emboj.2011.5. [PDB: 3q16] CMCF-ID Health
Quan, Shu; Koldewey, Philipp; Tapley, Tim; Kirsch, Nadine; Ruane, Karen M et al. (2011). Genetic selection designed to stabilize proteins uncovers a chaperone called Spy. Nature Structural and Molecular Biology 18(3) , 262-269. 10.1038/nsmb.2016. [PDB: 3o39] CMCF-ID Health