Publication Beamlines Strategic Pillar
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4720 1-(4-bromophenyl)-1H-imidazole. Protein Data Bank: 5ifc. CMCF-ID Health
Randriamihaja, Antsa (2017). Structural analyses of the ecto-nucleotides pyrophosphatases/phosphodiesterases 3 and 5. Supervisor: Nagar, Bhushan. QC, Canada: McGill University. https://escholarship.mcgill.ca/concern/theses/td96k517j. CMCF-ID Health
Radka; Christopher D. (2017). Structure/Function Studies of Yersinia pestis Metal Transport Systems. Supervisor: Aller, Stephen G.; DeLucas, Lawrence J.. Alabama, USA: University of Alabama at Birmingham. https://uab.primo.exlibrisgroup.com/permalink/01AL_UALB/5cjhn9/alma991002054550203176. CMCF-ID Agriculture
Planken, Simon; Behenna, Douglas C.; Nair, Sajiv K.; Johnson, Theodore O.; Nagata, Asako et al. (2017). Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR. Journal of Medicinal Chemistry 60(7) , 3002-3019. 10.1021/acs.jmedchem.6b01894. [PDB: 5ugc] CMCF-ID Health
Picard, M.-E.; Barma, J.; Shi, R. (2017). Crystal structure of CrmK, a flavoenzyme involved in the shunt product recycling mechanism in caerulomycin biosynthesis. Protein Data Bank: 5i1w. CMCF-ID Agriculture
Picard, M.-E.; Barma, J.; Shi, R. (2017). Crystal structure of CrmK, a flavoenzyme involved in the shunt product recycling mechanism in caerulomycin biosynthesis. Protein Data Bank: 5i1v. CMCF-ID Agriculture
Park, J.; Zielinski, M.; Tsantrizos, Y.S.; Berghuis, A.M. (2017). Crystal structure of human FPPS with allosterically bound FPP. Protein Data Bank: 5ja0. CMCF-ID Health
Park, J.; Magder, A.; Leung, C.Y.; Tsantrizos, Y.S.; Berghuis, A.M. et al. (2017). Crystal structure of human FPPS in complex with an allosteric inhibitor CL-06-057. Protein Data Bank: 5juz. CMCF-ID Health
Park, J.; Leung, C.Y.; Tsantrizos, Y.S.; Berghuis, A.M. (2017). Crystal structure of human FPPS in complex with an allosteric inhibitor CL-08-066. Protein Data Bank: 5jv1. CMCF-ID Health
Park, Jaeok; Zielinski, Michal; Magder, Alexandr; Tsantrizos, Youla S.; Berghuis, Albert M. et al. (2017). Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product. Nature Communications 8(1) . 10.1038/ncomms14132. [PDB: 5ja0] CMCF-ID Health
Park, Jaeok; Leung, Chun Yuen; Matralis, Alexios N.; Lacbay, Cyrus M.; Tsakos, Michail et al. (2017). Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. Journal of Medicinal Chemistry 60(5) , 2119-2134. 10.1021/acs.jmedchem.6b01888. [PDB: 5juz, 5jv1] CMCF-ID Health
Noach, Ilit; Ficko-Blean, Elizabeth; Pluvinage, Benjamin; Stuart, Christopher; Jenkins, Meredith L. et al. (2017). Recognition of protein-linked glycans as a determinant of peptidase activity. Proceedings of the National Academy of Sciences of the United States of America 114(5) , E679-E688. 10.1073/pnas.1615141114. [PDB: 5kd5, 5kd8, 5kdn, 5kdu, 5kdv, 5kdw, 5kdx] CMCF-BM, CMCF-ID Health
Noach, I.; Ficko-Blean, E.; Stuart, C.; Boraston, A.B. (2017). ZmpB metallopeptidase in complex with a2,6-Sialyl T-antigen. Protein Data Bank: 5kdu. CMCF-ID Agriculture
Noach, I.; Boraston, A.B. (2017). IMPa metallopeptidase from Pseudomonas aeruginosa. Protein Data Bank: 5kdw. CMCF-ID Agriculture
Noach, I.; Boraston, A.B. (2017). BT_4244 metallopeptidase in complex with Tn antigen.. Protein Data Bank: 5kd8. CMCF-ID Agriculture