Publication Beamlines Strategic Pillar
Bailey-Elkin; Ben (2018). Nidovirus papain-like proteases: structural insight into substrate recognition and innate immune suppression. Supervisor: Mark, Brian. Manitoba, Canada: University of Manitoba. http://hdl.handle.net/1993/32953. CMCF-BM, CMCF-ID Health
Blank, Matthew L.; Parker, Michelle L.; Ramaswamy, Raghavendran; Powell, Cameron J.; English, Elizabeth D. et al. (2018). A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions. Molecular Microbiology 108(5) , 519-535. 10.1111/mmi.13947. [PDB: 6bxr, 6bxs] CMCF-BM, CMCF-ID Health
Gebai, Ahmad; Gorelik, Alexei; Li, Zixian; Illes, Katalin; Nagar, Bhushan et al. (2018). Structural basis for the activation of acid ceramidase. Nature Communications 9(1) . 10.1038/s41467-018-03844-2. [PDB: 5u7z, 5u81, 5u84] CMCF-BM, CMCF-ID Health
Jacques, Benoit; Coinçon, Mathieu; Sygusch, Jurgen (2018). Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases. Journal of Biological Chemistry 293(20) , 7737-7753. 10.1074/jbc.ra117.001098. [PDB: 5ucn, 5ucp, 5ucs, 5ucz, 5ud0, 5ud1, 5ud2] CMCF-BM, CMCF-ID Health
Mellor, Paul; Marshall, Jeremy D. S.; Ruan, Xuan; Whitecross, Dielle E.; Ross, Rebecca L. et al. (2018). Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation. Scientific Reports 8(1) . 10.1038/s41598-018-25487-5. [PDB: 6d81, 6d82, 6d85, 6d86, 6d87] CMCF-BM, CMCF-ID Health
Yaseen; Ayat (2018). Part I: Crystallization of A Type IV Pilin from Pseudomonas Aeruginosa. Part II: Characterization of a Peptidyl-Prolyl-Cis,Trans-Isomerase Through X-Ray Crystallography. Supervisor: Audette, Gerald F. Ontario, Canada: York University. http://hdl.handle.net/10315/34570. CMCF-BM, CMCF-ID Agriculture
Alexander, J.A.N.; Strynadka, N.C.J. (2018). Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with nafcillin. Protein Data Bank: 5ty7. CMCF-ID Health
Alexander, J.A.N.; Strynadka, N.C.J. (2018). Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with ceftobiprole. Protein Data Bank: 5txi. CMCF-ID Health
Alexander, J.A.N.; Strynadka, N.C.J. (2018). Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with ceftobiprole. Protein Data Bank: 5tx9. CMCF-ID Health
Alexander, J.A.N.; Strynadka, N.C.J. (2018). Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with ceftaroline. Protein Data Bank: 5tw8. CMCF-ID Health
Alexander, J.A.N.; Strynadka, N.C.J. (2018). Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with ceftaroline. Protein Data Bank: 5tw4. CMCF-ID Health
Allingham, J.S.; Trofimova, D. (2018). Crystal structure of a curved tubulin complex induced by the kinesin-13 Kif2A. Protein Data Bank: 6bbn. CMCF-ID Health
Antonysamy, S. (2018). Structure of PRMT5:MEP50 in complex with LLY-283, a potent and selective inhibitor of PRMT5, with antitumor activity. Protein Data Bank: 6ckc. CMCF-ID Health
Bagal, Sharan K.; Andrews, Mark; Bechle, Bruce M.; Bian, Jianwei; Bilsland, James et al. (2018). Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain. Journal of Medicinal Chemistry 61(15) , 6779-6800. 10.1021/acs.jmedchem.8b00633. [PDB: 6dkb] CMCF-ID Health
Bagal, Sharan K.; Omoto, Kiyoyuki; Blakemore, David C.; Bungay, Peter J.; Bilsland, James G. et al. (2018). Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors. Journal of Medicinal Chemistry 62(1) , 247-265. 10.1021/acs.jmedchem.8b00280. [PDB: 6d20] CMCF-ID Health