Publication Beamlines Strategic Pillar
Keeling, Thomas J.; Samborska, Bożena; Demers, Ryan W.; Kimber, Matthew S. (2014). Interactions and structural variability of β-carboxysomal shell protein CcmL. Photosynthesis Research 121(2-3) , 125-133. 10.1007/s11120-014-9973-z. [PDB: 4n8f, 4n8x] CMCF-ID Agriculture
Zamyatkin, Dmitry; Rao, Chandni; Hoffarth, Elesha; Jurca, Gabriela; Rho, Hayeong et al. (2014). Structure of a backtracked state reveals conformational changes similar to the state following nucleotide incorporation in human norovirus polymerase. Acta Crystallographica Section D Biological Crystallography 70(12) , 3099-3109. 10.1107/s1399004714021518. [PDB: 4qpx] CMCF-ID Health
De Schutter, Joris W.; Park, Jaeok; Leung, Chun Yuen; Gormley, Patrick; Lin, Yih-Shyan et al. (2014). Multistage Screening Reveals Chameleon Ligands of the Human Farnesyl Pyrophosphate Synthase: Implications to Drug Discovery for Neurodegenerative Diseases. Journal of Medicinal Chemistry 57(13) , 5764-5776. 10.1021/jm500629e. [PDB: 4lpg, 4lph] CMCF-ID Health
Lau, Kelvin; Van Petegem, Filip (2014). Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain. Nature Communications 5(1) . 10.1038/ncomms6397. [PDB: 4p9i] CMCF-ID Health
Kalynych, Sergei; Cherney, Maia; Bostina, Mihnea; Rouiller, Isabelle; Cygler, Miroslaw et al. (2014). Quaternary structure of WzzB and WzzE polysaccharide copolymerases. Protein Science 24(1) , 58-69. 10.1002/pro.2586. CMCF-ID Health
Huh, Ian; Gene, Robert; Kumaran, Jyothi; MacKenzie, C. Roger; Brooks, Cory L. et al. (2014). In situproteolysis, crystallization and preliminary X-ray diffraction analysis of a VHH that binds listeria internalin B. Acta Crystallographica Section F:Structural Biology Communications 70(11) , 1532-1535. 10.1107/s2053230x1402010x. CMCF-ID Health
Parker, Matthew J; Gomery, Kathryn; Richard, Gabrielle; MacKenzie, C Roger; Cox, Andrew D et al. (2014). Structural basis for selective cross-reactivity in a bactericidal antibody against inner core lipooligosaccharide from Neisseria meningitidis†,‡. Glycobiology 24(5) , 442-449. 10.1093/glycob/cwu009. [PDB: 4c83, 4rqx] CMCF-ID Health
Duan, James J.-W.; Lu, Zhonghui; Jiang, Bin; Yang, Bingwei V.; Doweyko, Lidia M. et al. (2014). Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors. Bioorganic and Medicinal Chemistry Letters 24(24) , 5721-5726. 10.1016/j.bmcl.2014.10.061. [PDB: 4rio] CMCF-ID Health
Chamberlain, Philip P; Lopez-Girona, Antonia; Miller, Karen; Carmel, Gilles; Pagarigan, Barbra et al. (2014). Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs. Nature Structural and Molecular Biology 21(9) , 803-809. 10.1038/nsmb.2874. CMCF-ID Health
Yachnin, Brahm J.; McEvoy, Michelle B.; MacCuish, Roderick J. D.; Morley, Krista L.; Lau, Peter C. K. et al. (2014). Lactone-Bound Structures of Cyclohexanone Monooxygenase Provide Insight into the Stereochemistry of Catalysis. ACS Chemical Biology 9(12) , 2843-2851. 10.1021/cb500442e. [PDB: 4rg3] CMCF-ID Health
Gobeil, Sophie M.C.; Clouthier, Christopher M.; Park, Jaeok; Gagné, Donald; Berghuis, Albert M. et al. (2014). Maintenance of Native-like Protein Dynamics May Not Be Required for Engineering Functional Proteins. Chemistry & Biology 21(10) , 1330-1340. 10.1016/j.chembiol.2014.07.016. [PDB: 4id4] CMCF-ID Health
Leung, Kevin K. K.; Shilton, Brian H. (2014). Quinone Reductase 2 Is an Adventitious Target of Protein Kinase CK2 Inhibitors TBBz (TBI) and DMAT. Biochemistry 54(1) , 47-59. 10.1021/bi500959t. [PDB: 4u7h] CMCF-ID Health
Conly, Cuylar J. T.; Skovpen, Yulia V.; Li, Shuo; Palmer, David R. J.; Sanders, David A. R. et al. (2014). Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine. Biochemistry 53(47) , 7396-7406. 10.1021/bi5012157. [PDB: 4ly8, 4m19, 4mlj, 4mlr, 4r53] CMCF-BM, CMCF-ID Health
René, Olivier; Fauber, Benjamin P.; Boenig, Gladys de Leon; Burton, Brenda; Eidenschenk, Céline et al. (2014). Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action. ACS Medicinal Chemistry Letters 6(3) , 276-281. 10.1021/ml500420y. [PDB: 4wqp] CMCF-ID Health
Singh, Anirudh K.; Pluvinage, Benjamin; Higgins, Melanie A.; Dalia, Ankur B.; Woodiga, Shireen A. et al. (2014). Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus pneumoniae β-galactosidase, BgaA. PLoS Pathogens 10(9) , e1004364. 10.1371/journal.ppat.1004364. [PDB: 4cu9, 4cua, 4cub, 4cuc] CMCF-BM, CMCF-ID Health