Aydin, Halil; Sultana, Azmiri; Li, Sheng; Thavalingam, Annoj; Lee, Jeffrey E. et al. (2016). Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex. Nature 534(7608) , 562-565. 10.1038/nature18595. [PDB: 5f4e, 5f4t, 5f4v] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Bacik, John-Paul; Klesmith, Justin R.; Whitehead, Timothy A.; Jarboe, Laura R.; Unkefer, Clifford J. et al. (2015). Producing Glucose 6-Phosphate from Cellulosic Biomass. Journal of Biological Chemistry 290(44) , 26638-26648. 10.1074/jbc.m115.674614. [PDB: 4yh5, 4zfv, 4zlu, 5bsb] |
CMCF-ID |
Peer-Reviewed Article |
Agriculture |
Baker, Perrin; Whitfield, Gregory B.; Hill, Preston J.; Little, Dustin J.; Pestrak, Matthew J. et al. (2015). Characterization of the Pseudomonas aeruginosa Glycoside Hydrolase PslG Reveals That Its Levels Are Critical for Psl Polysaccharide Biosynthesis and Biofilm Formation. Journal of Biological Chemistry 290(47) , 28374-28387. 10.1074/jbc.m115.674929. [PDB: 5bxa] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Baugh, Loren; Phan, Isabelle; Begley, Darren W.; Clifton, Matthew C.; Armour, Brianna et al. (2015). Increasing the structural coverage of tuberculosis drug targets. Tuberculosis 95(2) , 142-148. 10.1016/j.tube.2014.12.003. [PDB: 3tx2] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Bergeron, Julien R.C.; Fernández, Lucia; Wasney, Gregory A.; Vuckovic, Marija; Reffuveille, Fany et al. (2016). The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing. Journal of Biological Chemistry 291(4) , 1676-1691. 10.1074/jbc.m115.684423. [PDB: 5cuk, 5cul] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Beyrakhova, Ksenia A.; van Straaten, Karin; Li, Lei; Boniecki, Michal T.; Anderson, Deborah H. et al. (2016). Structural and Functional Investigations of the Effector Protein LpiR1 from Legionella pneumophila. Journal of Biological Chemistry 291(30) , 15767-15777. 10.1074/jbc.m115.708701. [PDB: 5fia, 5jg4] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Blackler, Ryan J; Evans, Dylan W; Smith, David F; Cummings, Richard D; Brooks, Cory L et al. (2015). Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishesN-glycan phosphorylation in a branch-specific manner. Glycobiology 26(2) , 181-192. 10.1093/glycob/cwv093. [PDB: 4rzc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Blake, James F.; Burkard, Michael; Chan, Jocelyn; Chen, Huifen; Chou, Kang-Jye et al. (2016). Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development. Journal of Medicinal Chemistry 59(12) , 5650-5660. 10.1021/acs.jmedchem.6b00389. [PDB: 5k4i] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Bloudoff, Kristjan; Alonzo, Diego A.; Schmeing, T. Martin (2016). Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases. Cell Chemical Biology 23(3) , 331-339. 10.1016/j.chembiol.2016.02.012. [PDB: 5du9, 5dua] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Bloudoff, Kristjan; Fage, Christopher D.; Marahiel, Mohamed A.; Schmeing, T. Martin (2016). Structural and mutational analysis of the nonribosomal peptide synthetase heterocyclization domain provides insight into catalysis. Proceedings of the National Academy of Sciences of the United States of America 114(1) , 95-100. 10.1073/pnas.1614191114. [PDB: 5t3e] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Bryson, Steve; Thomson, Christy A.; Risnes, Louise F.; Dasgupta, Somnath; Smith, Kenneth et al. (2016). Structures of Preferred Human IgV Genes–Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation. Journal of Immunology 196(11) , 4723-4730. 10.4049/jimmunol.1402890. [PDB: 4hh9, 4hha] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Caldwell, Shane J.; Huang, Yue; Berghuis, Albert M. (2016). Antibiotic Binding Drives Catalytic Activation of Aminoglycoside Kinase APH(2″)-Ia. Structure 24(6) , 935-945. 10.1016/j.str.2016.04.002. [PDB: 5byl, 5iqa, 5iqb, 5iqc, 5iqd, 5iqe, 5iqg, 5iqh] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Calmettes, Charles; Ing, Christopher; Buckwalter, Carolyn M.; El Bakkouri, Majida; Chieh-Lin Lai, Christine et al. (2015). The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD. Nature Communications 6(1) . 10.1038/ncomms8996. [PDB: 4rdr, 4rvw] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Cappadocia, Laurent; Mascle, Xavier H.; Bourdeau, Véronique; Tremblay-Belzile, Samuel; Chaker-Margot, Malik et al. (2015). Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1. Structure 23(1) , 126-138. 10.1016/j.str.2014.10.015. [PDB: 4wjn] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Chan, Anson C.K.; Blair, Kris M.; Liu, Yanjie; Frirdich, Emilisa; Gaynor, Erin C. et al. (2015). Helical Shape of Helicobacter pylori Requires an Atypical Glutamine as a Zinc Ligand in the Carboxypeptidase Csd4. Journal of Biological Chemistry 290(6) , jbc.M114.624734. 10.1074/jbc.m114.624734. [PDB: 4wck, 4wcl, 4wcm, 4wcn] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |