Publication Beamlines Strategic Pillar
Caveney, Nathanael A.; Caballero, Guillermo; Voedts, Henri; Niciforovic, Ana; Worrall, Liam J. et al. (2019). Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nature Communications 10(1) . 10.1038/s41467-019-09507-0. [PDB: 6ntz] CMCF-BM, CMCF-ID Health
Caveney, Nathanael A.; Pavlin, Anja; Caballero, Guillermo; Bahun, Miha; Hodnik, Vesna et al. (2019). Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor. Structure 27(7) . 10.1016/j.str.2019.03.019. [PDB: 6n7o] CMCF-BM, CMCF-ID Health
Dong, Cheng; Nakagawa, Reiko; Oyama, Kyohei; Yamamoto, Yusuke; Zhang, Weilian et al. (2020). Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. eLife 9. 10.7554/elife.58675. [PDB: 6wat, 6wau] CMCF-BM, CMCF-ID Health
Doyle, Liam; Ovchinnikova, Olga G.; Myler, Katharine; Mallette, Evan; Huang, Bo-Shun et al. (2019). Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules. Nature Chemical Biology 15(6) . 10.1038/s41589-019-0276-8. [PDB: 6mgb, 6mgc, 6mgd] CMCF-BM, CMCF-ID Health
Ereño-Orbea, June; Sicard, Taylor; Cui, Hong; Mazhab-Jafari, Mohammad T.; Benlekbir, Samir et al. (2017). Molecular basis of human CD22 function and therapeutic targeting. Nature Communications 8(1) . 10.1038/s41467-017-00836-6. [PDB: 5vkj, 5vkk, 5vkm, 5vl3] CMCF-BM, CMCF-ID Health
Fedoretz-Maxwell, Brooklyn P.; Shin, Catherine H.; MacNeil, Gregory A.; Worrall, Liam J.; Park, Rachel et al. (2022). The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins. Inorganic Chemistry 61(14) , 5563-5571. 10.1021/acs.inorgchem.2c00030. [PDB: 7tc5] CMCF-BM, CMCF-ID Health
Feng, Yuting; Park, Jaeok; Li, Shi-Guang; Boutin, Rebecca; Viereck, Peter et al. (2019). Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). Journal of Medicinal Chemistry 62(21) , 9691-9702. 10.1021/acs.jmedchem.9b01104. [PDB: 6n7y, 6n82, 6n83, 6oag, 6oah] CMCF-BM, CMCF-ID Health
Forrester, Taylor J. B.; Ovchinnikova, Olga G.; Li, Zhixiong; Kitova, Elena N.; Nothof, Jeremy T. et al. (2022). The retaining β-Kdo glycosyltransferase WbbB uses a double-displacement mechanism with an intermediate adduct rearrangement step. Nature Communications 13(1) . 10.1038/s41467-022-33988-1. [PDB: 8csb, 8csc, 8csd, 8cse, 8csf] CMCF-BM, CMCF-ID Health
Gebai, Ahmad; Gorelik, Alexei; Li, Zixian; Illes, Katalin; Nagar, Bhushan et al. (2018). Structural basis for the activation of acid ceramidase. Nature Communications 9(1) . 10.1038/s41467-018-03844-2. [PDB: 5u7z, 5u81, 5u84] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Gebai, Ahmad; Illes, Katalin; Piomelli, Daniele; Nagar, Bhushan et al. (2018). Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proceedings of the National Academy of Sciences of the United States of America 115(43) , E10032-E10040. 10.1073/pnas.1811759115. [PDB: 6dxw, 6dxx, 6dxy, 6dxz, 6dy0, 6dy1, 6dy2, 6dy3] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Heinz, Leonhard X.; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal structure of mammalian acid sphingomyelinase. Nature Communications 7(1) . 10.1038/ncomms12196. [PDB: 5fi9, 5fib, 5fic, 5hqn] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan (2016). Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. Journal of Biological Chemistry 291(12) , 6376-6385. 10.1074/jbc.m115.711085. [PDB: 5fc1, 5fc6, 5fc7, 5fca, 5fcb] CMCF-BM, CMCF-ID Health
Heron, Paul W.; Abellán-Flos, Marta; Salmon, Laurent; Sygusch, Jurgen (2018). Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. Journal of Medicinal Chemistry 61(23) , 10558-10572. 10.1021/acs.jmedchem.8b01000. [PDB: 5tle, 5tlh, 5tlw, 5tlz] CMCF-BM, CMCF-ID Health
Hobbs, Joanne K.; Pluvinage, Benjamin; Robb, Melissa; Smith, Steven P.; Boraston, Alisdair B. et al. (2019). Two complementary α-fucosidases from Streptococcus pneumoniae promote complete degradation of host-derived carbohydrate antigens. Journal of Biological Chemistry 294(34) , jbc.RA119.009368. 10.1074/jbc.ra119.009368. [PDB: 6or4] CMCF-BM, CMCF-ID Health
Hu, Jinhong; Komakula, Aruna; Fraser, Marie E. (2017). Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallographica Section D: Structural Biology 73(8) , 660-671. 10.1107/s2059798317009871. [PDB: 5tde, 5tdf, 5tdm, 5tdz, 5te1, 5teq, 5tes, 5tet] CMCF-BM, CMCF-ID Health