Publication Beamlines Strategic Pillar
Zhou, Qun; Jaworski, Julie; Zhou, Yanfeng; Valente, Delphine; Cotton, Joanne et al. (2020). Engineered Fc-glycosylation switch to eliminate antibody effector function. mAbs 12(1) , 1814583. 10.1080/19420862.2020.1814583. [PDB: 6x3i] CMCF-ID Health
Zhao, Jianhua; Beyrakhova, Ksenia; Liu, Yao; Alvarez, Claudia P.; Bueler, Stephanie A. et al. (2017). Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein. PLoS Pathogens 13(6) , e1006394. 10.1371/journal.ppat.1006394. [PDB: 5uf5, 5ufk] CMCF-BM, CMCF-ID Health
Zhang, Y. (2018). N-terminal bromodomain of BRD4 in complex with PLX5981. Protein Data Bank: 5wma. CMCF-ID Health
Zhang, Wei; Bailey-Elkin, Ben A.; Knaap, Robert C. M.; Khare, Baldeep; Dalebout, Tim J. et al. (2017). Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants. PLoS Pathogens 13(5) , e1006372. 10.1371/journal.ppat.1006372. [PDB: 5v5g, 5v5h, 5v6a] CMCF-BM, CMCF-ID Health
Zhang, H.; Tempel, W.; Bountra, C.; Arrowsmith, C.H.; Edwards, A.M. et al. (2018). Crystal structure of an AF10 fragment. Protein Data Bank: 6cko. CMCF-ID Health
Zhang, Heng; Zhou, Bo; Qin, Su; Xu, Jing; Harding, Rachel et al. (2018). Structural and functional analysis of the DOT1L–AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis. Genes & Development 32(5-6) , 341-346. 10.1101/gad.311639.118. [PDB: 6cko] CMCF-ID Health
Zhang, Heng; Liu, Ke; Izumi, Natsuko; Huang, Haiming; Ding, Deqiang et al. (2017). Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2. Proceedings of the National Academy of Sciences of the United States of America 114(47) , 12483-12488. 10.1073/pnas.1711486114. [PDB: 5j39] CMCF-ID Health
Zhang, Birong; Kiefer, James R.; Blake, Robert A.; Chang, Jae H.; Hartman, Steven et al. (2019). Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha. Bioorganic and Medicinal Chemistry Letters 29(7) . 10.1016/j.bmcl.2019.01.036. [PDB: 6dfn] CMCF-ID Health
Zeng, H.; Dong, A.; Headey, S.; Gunzburg, M.; Doak, B. et al. (2020). Tudor Domain of Tumor suppressor p53BP1 with MFP-4184. Protein Data Bank: 6va5. CMCF-ID Health
Zarabi; Sarah Farshchi (2020). Preclinical Evaluation of a Novel Anti-leukemic Mechanism. Supervisor: Schimmer, Aaron D.. Ontario, Canada: University of Toronto. http://hdl.handle.net/1807/101294. CMCF-ID Health
Zara; Anthony (2018). Characterization of the interactions of a lignostilbene alpha-beta dioxygenase with both stilbene and carotenoid substrates. Supervisor: Loewen, Michele; Allingham, John. Ontario, Canada: Queen's University. http://hdl.handle.net/1974/24890. CMCF-ID Health
Yu, C.; Drobnick, J.; Bryan, M.C.; Kiefer, J.; Lupardus, P.J. et al. (2019). Structure of the IRAK4 kinase domain with compound 5. Protein Data Bank: 6o9d. CMCF-ID Health
Yeung, Kap-Sun; Beno, Brett R.; Parcella, Kyle; Bender, John A.; Grant-Young, Katherine A. et al. (2017). Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies. Journal of Medicinal Chemistry 60(10) , 4369-4385. 10.1021/acs.jmedchem.7b00328. [PDB: 5pzp] CMCF-ID Health
Yeung, Kap-Sun; Beno, Brett R.; Mosure, Kathy; Zhu, Juliang; Grant-Young, Katherine A. et al. (2018). Structure–Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B Inhibitors. ACS Medicinal Chemistry Letters 9(12) , 1217-1222. 10.1021/acsmedchemlett.8b00379. [PDB: 5qj0] CMCF-ID Health
Ye, Q.; Vance, T.D.R.; Davies, P.L. (2020). Crystal structure of tetra-tandem repeat in extending region of large adhesion protein. Protein Data Bank: 6xi3. CMCF-ID Health