Publication Beamlines Strategic Pillar
Aamudalapalli, Hari Babu; Bertwistle, Drew; Palmer, David R.J.; Sanders, David A.R. (2018). myo-Inositol dehydrogenase and scyllo-inositol dehydrogenase from Lactobacillus casei BL23 bind their substrates in very different orientations. Biochimica et Biophysica Acta - Proteins and Proteomics 1866(11) , 1115-1124. 10.1016/j.bbapap.2018.08.011. CMCF-ID Health
Alexander, J. Andrew N.; Chatterjee, Som S.; Hamilton, Stephanie M.; Eltis, Lindsay D.; Chambers, Henry F. et al. (2018). Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus. Journal of Biological Chemistry 293(51) , 19854-19865. 10.1074/jbc.ra118.004952. [PDB: 5tw4, 5tw8, 5tx9, 5txi, 5ty2, 5ty7, 6c39, 6c3k] CMCF-BM, CMCF-ID Health
Arnal, Gregory; Stogios, Peter J.; Asohan, Jathavan; Skarina, Tatiana; Savchenko, Alexei et al. (2018). Structural enzymology reveals the molecular basis of substrate regiospecificity and processivity of an exemplar bacterial glycoside hydrolase family 74 endo-xyloglucanase. Biochemical Journal 475(24) , 3963-3978. 10.1042/bcj20180763. [PDB: 6mgl] CMCF-ID Health
Beyrakhova, Ksenia; Li, Lei; Xu, Caishuang; Gagarinova, Alla; Cygler, Miroslaw et al. (2018). Legionella pneumophila effector Lem4 is a membrane-associated protein tyrosine phosphatase. Journal of Biological Chemistry 293(34) , 13044-13058. 10.1074/jbc.ra118.003845. [PDB: 6cdw, 6cgj] CMCF-ID Health
Blackler, Ryan J.; López-Guzmán, Arturo; Hager, Fiona F.; Janesch, Bettina; Martinz, Gudrun et al. (2018). Structural basis of cell wall anchoring by SLH domains in Paenibacillus alvei. Nature Communications 9(1) . 10.1038/s41467-018-05471-3. [PDB: 6cwc, 6cwh, 6cwi, 6cwl, 6cwm, 6cwn, 6cwr] CMCF-ID Health
Blank, Matthew L.; Parker, Michelle L.; Ramaswamy, Raghavendran; Powell, Cameron J.; English, Elizabeth D. et al. (2018). A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions. Molecular Microbiology 108(5) , 519-535. 10.1111/mmi.13947. [PDB: 6bxr, 6bxs] CMCF-BM, CMCF-ID Health
Caldwell, Shane J.; Berghuis, Albert M. (2018). Plasticity of Aminoglycoside Binding to Antibiotic Kinase APH(2″)-Ia. Antimicrobial Agents and Chemotherapy 62(7) , e00202-18. 10.1128/aac.00202-18. [PDB: 6c5u, 6cav, 6cey, 6cgd, 6cgg, 6ch4] CMCF-ID Health
Chen, Yun; Murillo-Solano, Claribel; Kirkpatrick, Melanie G.; Antoshchenko, Tetyana; Park, Hee-Won et al. (2018). Repurposing drugs to target the malaria parasite unfolding protein response. Scientific Reports 8(1) . 10.1038/s41598-018-28608-2. [PDB: 5umb] CMCF-ID Health
Chen, Yu Seby; Kozlov, Guennadi; Fakih, Rayan; Funato, Yosuke; Miki, Hiroaki et al. (2018). The cyclic nucleotide–binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg2+ efflux activity. Journal of Biological Chemistry 293(52) , 19998-20007. 10.1074/jbc.ra118.005672. [PDB: 6dj3] CMCF-ID Health
Dong, Cheng; Dong, Guangping; Li, Li; Zhu, Licheng; Tempel, Wolfram et al. (2018). An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2. Communications Biology 1(1) . 10.1038/s42003-018-0196-2. [PDB: 6dub] CMCF-ID Health
Dong, Cheng; Zhang, Heng; Li, Li; Tempel, Wolfram; Loppnau, Peter et al. (2018). Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway. Nature Chemical Biology 14(5) , 466-473. 10.1038/s41589-018-0036-1. [PDB: 6cdc] CMCF-ID Health
Ereño-Orbea, June; Sicard, Taylor; Cui, Hong; Carson, Jacob; Hermans, Pim et al. (2018). Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments. Journal of Molecular Biology 430(3) , 322-336. 10.1016/j.jmb.2017.12.010. [PDB: 6ana, 6and, 6ani] CMCF-ID Health
Gebai, Ahmad; Gorelik, Alexei; Li, Zixian; Illes, Katalin; Nagar, Bhushan et al. (2018). Structural basis for the activation of acid ceramidase. Nature Communications 9(1) . 10.1038/s41467-018-03844-2. [PDB: 5u7z, 5u81, 5u84] CMCF-BM, CMCF-ID Health
Gebai, Ahmad; Gorelik, Alexei; Nagar, Bhushan (2018). Crystal structure of saposin D in an open conformation. Journal of Structural Biology 204(2) , 145-150. 10.1016/j.jsb.2018.07.011. [PDB: 5u85] CMCF-ID Health
González, Javier M.; Marti-Arbona, Ricardo; Chen, Julian C.-H.; Broom-Peltz, Brian; Unkefer, Clifford J. et al. (2018). Conformational changes on substrate binding revealed by structures of Methylobacterium extorquens malate dehydrogenase. Acta Crystallographica Section F:Structural Biology Communications 74(10) , 610-616. 10.1107/s2053230x18011809. [PDB: 5ujk] CMCF-ID Health