Publication Beamlines Strategic Pillar
Ahmad, Shehryar; Tsang, Kara K; Sachar, Kartik; Quentin, Dennis; Tashin, Tahmid M et al. (2020). Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones. eLife 9. 10.7554/elife.62816. [PDB: 6xrr] CMCF-ID Health
Akaki, Tatsuo; Bessho, Yuki; Ito, Takashi; Fujioka, Shingo; Ubukata, Minoru et al. (2021). Fragment-based lead discovery to identify novel inhibitors that target the ATP binding site of pyruvate dehydrogenase kinases. Bioorganic and Medicinal Chemistry 44, 116283. 10.1016/j.bmc.2021.116283. [PDB: 7ebb] CMCF-ID Health
Almawi, Ahmad W; Scotland, Michelle K; Randall, Justin R; Liu, Linda; Martin, Heather K et al. (2019). Binding of the regulatory domain of MutL to the sliding β-clamp is species specific. Nucleic Acids Research 47(9) . 10.1093/nar/gkz115. [PDB: 6e8d, 6e8e] CMCF-BM, CMCF-ID Health
Alonzo, Diego A.; Chiche-Lapierre, Clarisse; Tarry, Michael J.; Wang, Jimin; Schmeing, T. Martin et al. (2020). Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nature Chemical Biology 16(5) . 10.1038/s41589-020-0481-5. [PDB: 6ulz] CMCF-ID Health
Anderson, Alexander C.; Burnett, Alysha J.N.; Hiscock, Lana; Maly, Kenneth E.; Weadge, Joel T. et al. (2020). The Escherichia coli cellulose synthase subunit G (BcsG) is a Zn2+-dependent phosphoethanolamine transferase. Journal of Biological Chemistry 295(18) , 6225-6235. 10.1074/jbc.ra119.011668. [PDB: 6pcz, 6pd0] CMCF-ID Health
Arnal, Gregory; Stogios, Peter J.; Asohan, Jathavan; Attia, Mohamed A.; Skarina, Tatiana et al. (2019). Substrate specificity, regiospecificity, and processivity in glycoside hydrolase family 74. Journal of Biological Chemistry 294(36) , jbc.RA119.009861. 10.1074/jbc.ra119.009861. [PDB: 6p2l, 6p2o] CMCF-ID Health
Bailey-Elkin, Ben A.; Knaap, Robert C. M.; De Silva, Anuradha; Boekhoud, Ilse M.; Mous, Sandra et al. (2023). Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis. PLoS Pathogens 19(12) , e1011872. 10.1371/journal.ppat.1011872. [PDB: 8ehn] CMCF-ID Health
Bateman, Thomas J.; Shah, Megha; Ho, Timothy Pham; Shin, Hyejin Esther; Pan, Chuxi et al. (2021). A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii. Nature Communications 12(1) . 10.1038/s41467-021-26545-9. [PDB: 7re4, 7rea, 7red] CMCF-BM, CMCF-ID Health
Beenstock, Jonah; Ona, Samara Mishelle; Porat, Jennifer; Orlicky, Stephen; Wan, Leo C. K. et al. (2020). A substrate binding model for the KEOPS tRNA modifying complex. Nature Communications 11(1) . 10.1038/s41467-020-19990-5. [PDB: 7kju] CMCF-ID Health
Beshore, Douglas C.; Adam, Gregory C.; Barnard, Richard J. O.; Burlein, Christine; Gallicchio, Steven N. et al. (2021). Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction. ACS Medicinal Chemistry Letters 12(4) , 540-547. 10.1021/acsmedchemlett.1c00074. [PDB: 7ltg] CMCF-ID Health
Boddington, Kelly F.; Soubeyrand, Eric; Van Gelder, Kristen; Casaretto, José A.; Perrin, Colby et al. (2021). Bibenzyl synthesis in Cannabis sativa L.. Plant Journal 109(3) . 10.1111/tpj.15588. [PDB: 7sgy] CMCF-ID Agriculture
Borsari, Chiara; Keles, Erhan; McPhail, Jacob A.; Schaefer, Alexander; Sriramaratnam, Rohitha et al. (2022). Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα. Journal of the American Chemical Society 144(14) . 10.1021/jacs.1c13568. [PDB: 7r9v, 7r9y] CMCF-ID Health
Bryan, Marian C.; Drobnick, Joy; Gobbi, Alberto; Kolesnikov, Aleksandr; Chen, Yongsheng et al. (2019). Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors. Journal of Medicinal Chemistry 62(13) . 10.1021/acs.jmedchem.9b00439. [PDB: 6o9d] CMCF-ID Health
Bullen, Nathan P.; Sychantha, David; Thang, Stephanie S.; Culviner, Peter H.; Rudzite, Marta et al. (2022). An ADP-ribosyltransferase toxin kills bacterial cells by modifying structured non-coding RNAs. Molecular Cell 82(18) , 3484-3498.e11. 10.1016/j.molcel.2022.08.015. CMCF-ID Health
Candito, David A.; Simov, Vladimir; Gulati, Anmol; Kattar, Solomon; Chau, Ryan W. et al. (2022). Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease. Journal of Medicinal Chemistry 65(24) , 16801-16817. 10.1021/acs.jmedchem.2c01605. [PDB: 8e80] CMCF-ID Health