Publication Beamlines Strategic Pillar
Akaki, Tatsuo; Bessho, Yuki; Ito, Takashi; Fujioka, Shingo; Ubukata, Minoru et al. (2021). Fragment-based lead discovery to identify novel inhibitors that target the ATP binding site of pyruvate dehydrogenase kinases. Bioorganic and Medicinal Chemistry 44, 116283. 10.1016/j.bmc.2021.116283. [PDB: 7ebb] CMCF-ID Health
Ali, Mohamed G.; Wahba, Haytham M.; Igelmann, Sebastian; Cyr, Normand; Ferbeyre, Gerardo et al. (2024). Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR. Autophagy . 10.1080/15548627.2024.2353443. [PDB: 8t33, 8t4t] CMCF-BM, CMCF-ID Health
Bailey-Elkin, Ben A.; Knaap, Robert C. M.; De Silva, Anuradha; Boekhoud, Ilse M.; Mous, Sandra et al. (2023). Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis. PLoS Pathogens 19(12) , e1011872. 10.1371/journal.ppat.1011872. [PDB: 8ehn] CMCF-ID Health
Bateman, Thomas J.; Shah, Megha; Ho, Timothy Pham; Shin, Hyejin Esther; Pan, Chuxi et al. (2021). A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii. Nature Communications 12(1) . 10.1038/s41467-021-26545-9. [PDB: 7re4, 7rea, 7red] CMCF-BM, CMCF-ID Health
Boddington, Kelly F.; Soubeyrand, Eric; Van Gelder, Kristen; Casaretto, José A.; Perrin, Colby et al. (2021). Bibenzyl synthesis in Cannabis sativa L.. Plant Journal 109(3) . 10.1111/tpj.15588. [PDB: 7sgy] CMCF-ID Agriculture
Borsari, Chiara; Keles, Erhan; McPhail, Jacob A.; Schaefer, Alexander; Sriramaratnam, Rohitha et al. (2022). Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα. Journal of the American Chemical Society 144(14) . 10.1021/jacs.1c13568. [PDB: 7r9v, 7r9y] CMCF-ID Health
Bullen, Nathan P.; Sychantha, David; Thang, Stephanie S.; Culviner, Peter H.; Rudzite, Marta et al. (2022). An ADP-ribosyltransferase toxin kills bacterial cells by modifying structured non-coding RNAs. Molecular Cell 82(18) , 3484-3498.e11. 10.1016/j.molcel.2022.08.015. CMCF-ID Health
Chen, Yu Seby; Kozlov, Guennadi; Moeller, Brandon E.; Rohaim, Ahmed; Fakih, Rayan et al. (2021). Crystal structure of an archaeal CorB magnesium transporter. Nature Communications 12(1) . 10.1038/s41467-021-24282-7. [PDB: 7m1t, 7m1u] CMCF-ID Health
Chung, Ivy Y. W.; Li, Lei; Tyurin, Oleg; Gagarinova, Alla; Wibawa, Raissa et al. (2021). Structural and functional study of Legionella pneumophila effector RavA. Protein Science 30(5) . 10.1002/pro.4057. [PDB: 6wo6] CMCF-ID Health
Colautti, Jake; Bullen, Nathan P.; Whitney, John C. (2023). Lack of evidence that Pseudomonas aeruginosa AmpDh3‐PA0808 constitute a type VI secretion system effector–immunity pair. Molecular Microbiology . 10.1111/mmi.15021. [PDB: 8es5] CMCF-ID Health
Cook, Jonathan D.; Khondker, Adree; Lee, Jeffrey E. (2022). Conformational plasticity of the HIV-1 gp41 immunodominant region is recognized by multiple non-neutralizing antibodies. Communications Biology 5(1) . 10.1038/s42003-022-03235-w. [PDB: 7n04, 7n05, 7n07, 7n08] CMCF-ID Health
Cottrell, Kevin M.; Briggs, Kimberly J.; Whittington, Douglas A.; Jahic, Haris; Ali, Janid A. et al. (2024). Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted Cancers. Journal of Medicinal Chemistry 67(8) , 6064-6080. 10.1021/acs.jmedchem.4c00133. [PDB: 8veu] CMCF-ID Health
Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). An imine reductase that captures reactive intermediates in the biosynthesis of the indolocarbazole reductasporine. Journal of Biological Chemistry , 105642. 10.1016/j.jbc.2024.105642. CMCF-ID Health
Doyle, Liam; Ovchinnikova, Olga G.; Huang, Bo-Shun; Forrester, Taylor J.B.; Lowary, Todd L. et al. (2023). Mechanism and linkage specificities of the dual retaining β-Kdo glycosyltransferase modules of KpsC from bacterial capsule biosynthesis. Journal of Biological Chemistry , 104609. 10.1016/j.jbc.2023.104609. [PDB: 8fuw, 8fux] CMCF-ID Health
Ereño-Orbea, June; Liu, Xianglei; Sicard, Taylor; Kucharska, Iga; Li, Wei et al. (2021). Structural details of monoclonal antibody m971 recognition of the membrane-proximal domain of CD22. Journal of Biological Chemistry 297(2) , 100966. 10.1016/j.jbc.2021.100966. [PDB: 7o4y, 7o52] CMCF-ID Health