Publication Beamlines Strategic Pillar
Chen, Meixia; Wang, Zhuowen; Li, Weiguo; Chen, Yichang; Xiao, Qin et al. (2023). Crystal structure of Tudor domain of TDRD3 in complex with a small molecule antagonist. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1866(3) , 194962. 10.1016/j.bbagrm.2023.194962. [PDB: 8jtn] CMCF-ID Health
Chen, M.; Wang, Z.; Li, W.; Shang, X.; Liu, Y. et al. (2023). Tudor domain of TDRD3 in complex with a small molecule. Protein Data Bank: 8jtn. CMCF-ID Health
Chew, Kylie S.; Wells, Robert C.; Moshkforoush, Arash; Chan, Darren; Lechtenberg, Kendra J. et al. (2023). CD98hc is a target for brain delivery of biotherapeutics. Nature Communications 14(1) . 10.1038/s41467-023-40681-4. [PDB: 8g0m] CMCF-ID Health
Cole, Andrew G.; Kultgen, Steven G.; Mani, Nagraj; Quintero, Jorge G.; Yi Fan, Kristi et al. (2023). Design, synthesis, and structure-activity relationship of a bicyclic HBV capsid assembly modulator chemotype leading to the identification of clinical candidate AB-506. Bioorganic and Medicinal Chemistry Letters 94, 129456. 10.1016/j.bmcl.2023.129456. [PDB: 8gbu] CMCF-ID Health
Dementiev, A.A.; Michino, M.; Vendome, J.; Ginn, J.; Bryk, R. et al. (2024). Co-crystal structure of optimized analog TDI-13537 provided new insights into the potency determinants of the sulfonamide inhibitor series. Protein Data Bank: 8u0q. CMCF-ID Agriculture
Duvall, Jeremy R.; Thomas, Joshua D.; Bukhalid, Raghida A.; Catcott, Kalli C.; Bentley, Keith W. et al. (2023). Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c00907. [PDB: 8sth] CMCF-ID Health
Duvall, J.R.; Bukhalid, R.A. (2023). human STING with diABZI agonist 15. Protein Data Bank: 8sth. CMCF-ID Health
Ghosh, K. (2024). Human CK1 Delta Kinase structure bound to Inhibitor. Protein Data Bank: 8izc. CMCF-ID Health
Gui, Wenjun; Hang, Yumo; Cheng, Wang; Gao, Minqi; Wu, Jiaquan et al. (2023). Structural basis of CDK3 activation by cyclin E1 and inhibition by dinaciclib. Biochemical and Biophysical Research Communications 662, 126-134. 10.1016/j.bbrc.2023.04.026. CMCF-BM, CMCF-ID Health
Gui, W.; Wang, F.; Cheng, W.; Gao, J.; Huang, Y. et al. (2023). The Crystal Structure of CDK3 and CyclinE1 Complex with Dinaciclib from Biortus. Protein Data Bank: 8h4r. CMCF-ID Agriculture
Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 crystal structure with fragment bound (compound 14). Protein Data Bank: 8t5m. CMCF-ID Agriculture
Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 co-crystal structure with fragment bound (compound 12). Protein Data Bank: 8t5g. CMCF-ID Agriculture
He, Liqi; Zhang, Meng Yao; Cox, Matthew; Zhang, Qian; Donnell, Andrew F. et al. (2024). Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology. ACS Medicinal Chemistry Letters 15(2) , 189-196. 10.1021/acsmedchemlett.3c00456. [PDB: 8s9h] CMCF-ID Health
Holden, J.K.; Partridge, J.R.; Wibowo, A.S.; Mulichak, A. (2024). Ubiquitin variant i53 mutant L67R bound to 53BP1 Tudor Domain. Protein Data Bank: 8svh. CMCF-ID Agriculture
Holden, J.K.; Partridge, J.R.; Wibowo, A.S.; Mulichak, A. (2024). Ubiquitin variant i53 in complex with 53BP1 Tudor domain. Protein Data Bank: 8svg. CMCF-ID Agriculture