Publication Beamlines Strategic Pillar
Lang, Shenhui; Cressatti, Marisa; Mendoza, Kris E.; Coumoundouros, Chelsea N.; Plater, Samantha M. et al. (2015). YehZYXW of Escherichia coli Is a Low-Affinity, Non-Osmoregulatory Betaine-Specific ABC Transporter. Biochemistry 54(37) , 5735-5747. 10.1021/acs.biochem.5b00274. [PDB: 4wep] CMCF-ID Health
Ren, Li; Grina, Jonas; Moreno, David; Blake, James F.; Gaudino, John J. et al. (2015). Discovery of Highly Potent, Selective, and Efficacious Small Molecule Inhibitors of ERK1/2. Journal of Medicinal Chemistry 58(4) , 1976-1991. 10.1021/jm501921k. [PDB: 4xj0] CMCF-ID Health
Bacik, John-Paul; Klesmith, Justin R.; Whitehead, Timothy A.; Jarboe, Laura R.; Unkefer, Clifford J. et al. (2015). Producing Glucose 6-Phosphate from Cellulosic Biomass. Journal of Biological Chemistry 290(44) , 26638-26648. 10.1074/jbc.m115.674614. [PDB: 4yh5, 4zfv, 4zlu, 5bsb] CMCF-ID Agriculture
Ndubaku, Chudi O.; Crawford, James J.; Drobnick, Joy; Aliagas, Ignacio; Campbell, David et al. (2015). Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pKa Polar Moiety. ACS Medicinal Chemistry Letters 6(12) , 1241-1246. 10.1021/acsmedchemlett.5b00398. CMCF-ID Health
Robb, Melissa; Robb, Craig S.; Higgins, Melanie A.; Hobbs, Joanne K.; Paton, James C. et al. (2015). A Second β-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans. Journal of Biological Chemistry 290(52) , 30888-30900. 10.1074/jbc.m115.688630. [PDB: 5a6a, 5a6b, 5a6k, 5ac5] CMCF-ID Health
Baker, Perrin; Whitfield, Gregory B.; Hill, Preston J.; Little, Dustin J.; Pestrak, Matthew J. et al. (2015). Characterization of the Pseudomonas aeruginosa Glycoside Hydrolase PslG Reveals That Its Levels Are Critical for Psl Polysaccharide Biosynthesis and Biofilm Formation. Journal of Biological Chemistry 290(47) , 28374-28387. 10.1074/jbc.m115.674929. [PDB: 5bxa] CMCF-ID Health
Yao, Deqiang; Zhang, Tao; He, Yao; Han, Pu; Cherney, Maia et al. (2014). A case study on the treatment of protein SIRAS data. Acta Crystallographica Section D Biological Crystallography 70(10) , 2686-2691. 10.1107/s1399004714017271. CMCF-BM, CMCF-ID Materials
Orriss, George L.; Patel, Trushar R.; Sorensen, John; Stetefeld, Jörg (2009). Absence of a catalytic water confers resistance to the neurotoxin gabaculine. FASEB Journal 24(2) , 404-414. 10.1096/fj.09-138297. CMCF-ID Health
Eble, Johannes A.; Niland, Stephan; Bracht, Thilo; Mormann, Michael; Peter-Katalinic, Jasna et al. (2009). The α2β1 integrin‐specific antagonist rhodocetin is a cruciform, heterotetrameric molecule. FASEB Journal 23(9) , 2917-2927. 10.1096/fj.08-126763. CMCF-ID Health
Yuchi, Zhiguang; Yuen, Siobhan M. Wong King; Lau, Kelvin; Underhill, Ainsley Q.; Cornea, Razvan L. et al. (2015). Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant. Nature Communications 6(1) . 10.1038/ncomms8947. CMCF-ID Health
Ravulapalli, Ravikiran; Lugo, Miguel R.; Pfoh, Roland; Visschedyk, Danielle; Poole, Amanda et al. (2015). Characterization of Vis Toxin, a Novel ADP-Ribosyltransferase from Vibrio splendidus. Biochemistry 54(38) , 5920-5936. 10.1021/acs.biochem.5b00921. [PDB: 4y1w, 4yc0] CMCF-ID Health
Gregg, Katie J.; Suits, Michael D.L.; Deng, Lehua; Vocadlo, David J.; Boraston, Alisdair B. et al. (2015). Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights into Its Mechanism. Journal of Biological Chemistry 290(42) , 25657-25669. 10.1074/jbc.m115.680470. CMCF-ID Health
D’Costa, Vanessa M.; Braun, Virginie; Landekic, Marija; Shi, Rong; Proteau, Ariane et al. (2015). Salmonella Disrupts Host Endocytic Trafficking by SopD2-Mediated Inhibition of Rab7. Cell Reports 12(9) , 1508-1518. 10.1016/j.celrep.2015.07.063. [PDB: 5cq9] CMCF-ID Health
Wan, Honghe; Schroeder, Gretchen M.; Hart, Amy C.; Inghrim, Jennifer; Grebinski, James et al. (2015). Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms. ACS Medicinal Chemistry Letters 6(8) , 850-855. 10.1021/acsmedchemlett.5b00226. [PDB: 5cf8] CMCF-ID Health
Farha, Maya A.; Czarny, Tomasz L.; Myers, Cullen L.; Worrall, Liam J.; French, Shawn et al. (2015). Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase. Proceedings of the National Academy of Sciences of the United States of America 112(35) , 11048-11053. 10.1073/pnas.1511751112. [PDB: 5cqb, 5cqj] CMCF-ID Health