Vinogradova, Maia; Gehling, Victor S; Gustafson, Amy; Arora, Shilpi; Tindell, Charles A et al. (2016). An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells. Nature Chemical Biology 12(7) , 531-538. 10.1038/nchembio.2085. [PDB: 5ceh] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Vashchenko, Ganna; Das, Samir; Moon, Kyung-Mee; Rogalski, Jason C.; Taves, Matthew D. et al. (2016). Identification of Avian Corticosteroid-binding Globulin (SerpinA6) Reveals the Molecular Basis of Evolutionary Adaptations in SerpinA6 Structure and Function as a Steroid-binding Protein. Journal of Biological Chemistry 291(21) , 11300-11312. 10.1074/jbc.m116.714378. [PDB: 5hgc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Tebben, Andrew J.; Ruzanov, Maxim; Gao, Mian; Xie, Dianlin; Kiefer, Susan E. et al. (2016). Crystal structures of apo and inhibitor-bound TGFβR2 kinase domain: insights into TGFβR isoform selectivity. Acta Crystallographica Section D: Structural Biology 72(5) , 658-674. 10.1107/s2059798316003624. [PDB: 5e8u] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Roach, Elyse J.; Wroblewski, Charles; Seidel, Laura; Berezuk, Alison M.; Brewer, Dyanne et al. (2016). Structure and Mutational Analyses of Escherichia coli ZapD Reveal Charged Residues Involved in FtsZ Filament Bundling. Journal of Bacteriology 198(11) , 1683-1693. 10.1128/jb.00969-15. [PDB: 5dko] |
CMCF-ID |
Peer-Reviewed Article |
Agriculture |
Ovchinnikova, Olga G.; Mallette, Evan; Koizumi, Akihiko; Lowary, Todd L.; Kimber, Matthew S. et al. (2016). Bacterial β-Kdo glycosyltransferases represent a new glycosyltransferase family (GT99). Proceedings of the National Academy of Sciences of the United States of America 113(22) , 3120-3129. 10.1073/pnas.1603146113. [PDB: 5fa0, 5fa1] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Nicklisch, Sascha C. T.; Rees, Steven D.; McGrath, Aaron P.; Gökirmak, Tufan; Bonito, Lindsay T. et al. (2016). Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure. Science advances 2(4) , e1600001-e1600001. 10.1126/sciadv.1600001. [PDB: 4xwk] |
CMCF-ID |
Peer-Reviewed Article |
Environment |
Mazurkewich, Scott; Brott, Ashley S.; Kimber, Matthew S.; Seah, Stephen Y.K. (2016). Structural and Kinetic Characterization of the 4-Carboxy-2-hydroxymuconate Hydratase from the Gallate and Protocatechuate 4,5-Cleavage Pathways of Pseudomonas putida KT2440. Journal of Biological Chemistry 291(14) , 7669-7686. 10.1074/jbc.m115.682054. [PDB: 5cgz] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Mann, Paul A.; Müller, Anna; Wolff, Kerstin A.; Fischmann, Thierry; Wang, Hao et al. (2016). Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets. PLoS Pathogens 12(5) , e1005585. 10.1371/journal.ppat.1005585. [PDB: 5enz] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Lyons, Bronwyn; Ravulapalli, Ravikiran; Lanoue, Jason; Lugo, Miguel R.; Dutta, Debajyoti et al. (2016). Scabin, a Novel DNA-acting ADP-ribosyltransferase from Streptomyces scabies. Journal of Biological Chemistry 291(21) , 11198-11215. 10.1074/jbc.m115.707653. [PDB: 5daz, 5ewk, 5ewy] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Lugo, Miguel R.; Ravulapalli, Ravikiran; Dutta, Debajyoti; Rod Merrill, A. (2016). Structural variability of C3larvin toxin. Intrinsic dynamics of the α/β fold of the C3-like group of mono-ADP-ribosyltransferase toxins. Journal of Biomolecular Structure and Dynamics , 2537-2560. 10.1080/07391102.2015.1123189. [PDB: 5dzq] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Liu, Longbin; Lee, Matthew R.; Kim, Joseph L.; Whittington, Douglas A.; Bregman, Howard et al. (2016). Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling. Bioorganic and Medicinal Chemistry 24(10) , 2215-2234. 10.1016/j.bmc.2016.03.055. [PDB: 5fd2] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Leaver-Fay, Andrew; Froning, Karen J.; Atwell, Shane; Aldaz, Hector; Pustilnik, Anna et al. (2016). Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure 24(4) , 641-651. 10.1016/j.str.2016.02.013. [PDB: 5dj0, 5dj2] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Materials |
Jha, Vikash; Bian, Chuanbing; Xing, Guangxin; Ling, Hong (2016). Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase κ. Nucleic Acids Research 44(10) , 4957-4967. 10.1093/nar/gkw204. [PDB: 4u6p, 4u7c] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Hughes, Scott J.; Antoshchenko, Tetyana; Chen, Yun; Lu, Hua; Pizarro, Juan C. et al. (2016). Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs. PLoS ONE 11(5) , e0154862. 10.1371/journal.pone.0154862. [PDB: 5evz, 5ex5, 5exw, 5f0x, 5f2r] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Hobbs, Joanne K.; Lee, Seunghyae M.; Robb, Melissa; Hof, Fraser; Barr, Christopher et al. (2016). KdgF, the missing link in the microbial metabolism of uronate sugars from pectin and alginate. Proceedings of the National Academy of Sciences of the United States of America 113(22) , 6188-6193. 10.1073/pnas.1524214113. [PDB: 5fpx, 5fpz] |
CMCF-ID |
Peer-Reviewed Article |
Materials |