Publication Beamlines Strategic Pillar
Akaki, Tatsuo; Bessho, Yuki; Ito, Takashi; Fujioka, Shingo; Ubukata, Minoru et al. (2021). Fragment-based lead discovery to identify novel inhibitors that target the ATP binding site of pyruvate dehydrogenase kinases. Bioorganic and Medicinal Chemistry 44, 116283. 10.1016/j.bmc.2021.116283. [PDB: 7ebb] CMCF-ID Health
Bateman, Thomas J.; Shah, Megha; Ho, Timothy Pham; Shin, Hyejin Esther; Pan, Chuxi et al. (2021). A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii. Nature Communications 12(1) . 10.1038/s41467-021-26545-9. [PDB: 7re4, 7rea, 7red] CMCF-BM, CMCF-ID Health
Boddington, Kelly F.; Soubeyrand, Eric; Van Gelder, Kristen; Casaretto, José A.; Perrin, Colby et al. (2021). Bibenzyl synthesis in Cannabis sativa L.. Plant Journal 109(3) . 10.1111/tpj.15588. [PDB: 7sgy] CMCF-ID Agriculture
Chen, Yu Seby; Kozlov, Guennadi; Moeller, Brandon E.; Rohaim, Ahmed; Fakih, Rayan et al. (2021). Crystal structure of an archaeal CorB magnesium transporter. Nature Communications 12(1) . 10.1038/s41467-021-24282-7. [PDB: 7m1t, 7m1u] CMCF-ID Health
Chung, Ivy Y. W.; Li, Lei; Tyurin, Oleg; Gagarinova, Alla; Wibawa, Raissa et al. (2021). Structural and functional study of Legionella pneumophila effector RavA. Protein Science 30(5) . 10.1002/pro.4057. [PDB: 6wo6] CMCF-ID Health
Ereño-Orbea, June; Liu, Xianglei; Sicard, Taylor; Kucharska, Iga; Li, Wei et al. (2021). Structural details of monoclonal antibody m971 recognition of the membrane-proximal domain of CD22. Journal of Biological Chemistry 297(2) , 100966. 10.1016/j.jbc.2021.100966. [PDB: 7o4y, 7o52] CMCF-ID Health
Freibert, Sven-A.; Boniecki, Michal T.; Stümpfig, Claudia; Schulz, Vinzent; Krapoth, Nils et al. (2021). N-terminal tyrosine of ISCU2 triggers [2Fe-2S] cluster synthesis by ISCU2 dimerization. Nature Communications 12(1) . 10.1038/s41467-021-27122-w. CMCF-ID Health
Golkar, Tolou; Bassenden, Angelia V.; Maiti, Krishnagopal; Arya, Dev P.; Schmeing, T. Martin et al. (2021). Structural basis for plazomicin antibiotic action and resistance. Communications Biology 4(1) . 10.1038/s42003-021-02261-4. [PDB: 6vou, 7lh5] CMCF-ID Health
Guo, Shuaiqi; Vance, Tyler D. R.; Zahiri, Hossein; Eves, Robert; Stevens, Corey et al. (2021). Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation. mBio 12(2) . 10.1128/mbio.00130-21. [PDB: 6x7j, 6x7t, 6x7y, 6x7z, 6x8a, 6x8d, 6x8y, 6x95, 6x9m, 6x9p, 6xa5, 6xaq] CMCF-ID Health
Higgins, Melanie A.; Tegl, Gregor; MacDonald, Spencer S.; Arnal, Gregory; Brumer, Harry et al. (2021). N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes. ACS Chemical Biology 16(4) . 10.1021/acschembio.0c00995. [PDB: 7lqx, 7lr1] CMCF-ID Health
Huang, Ji; Fraser, Marie E. (2021). Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase. Acta Crystallographica Section D: Structural Biology 77(3) , 357-368. 10.1107/s2059798321000334. [PDB: 7jj0, 7jkr] CMCF-ID Health
Li, Franco K.K.; Gale, Robert T.; Petrotchenko, Evgeniy V.; Borchers, Christoph H.; Brown, Eric D. et al. (2021). Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis. Journal of Structural Biology 213(2) , 107733. 10.1016/j.jsb.2021.107733. [PDB: 6xh9, 6xhk, 6xhp, 6xhq, 6xhr, 6xhs, 6xht] CMCF-ID Health
Majewski, Dorothy D.; Okon, Mark; Heinkel, Florian; Robb, Craig S.; Vuckovic, Marija et al. (2021). Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods. Structure 29(2) . 10.1016/j.str.2020.08.006. [PDB: 6xfj] CMCF-BM, CMCF-ID Health
Mulligan, Vikram Khipple; Workman, Sean; Sun, Tianjun; Rettie, Stephen; Li, Xinting et al. (2021). Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1. Proceedings of the National Academy of Sciences of the United States of America 118(12) , e2012800118. 10.1073/pnas.2012800118. [PDB: 6xbe, 6xbf] CMCF-ID Health
Naineni, Sai Kiran; Liang, Jason; Hull, Kenneth; Cencic, Regina; Zhu, Mingzhao et al. (2021). Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A. Cell Chemical Biology 28(6) . 10.1016/j.chembiol.2020.12.006. [PDB: 6xki] CMCF-ID Health