| Smith, Christopher R.; Chen, Dan; Christensen, James G.; Coulombe, René; Féthière, James et al. (2023). Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. Journal of Medicinal Chemistry 67(1) , 774-781. 10.1021/acs.jmedchem.3c02140. [PDB: 8t5g, 8t5m, 8t5r] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Gui, Wenjun; Hang, Yumo; Cheng, Wang; Gao, Minqi; Wu, Jiaquan et al. (2023). Structural basis of CDK3 activation by cyclin E1 and inhibition by dinaciclib. Biochemical and Biophysical Research Communications 662, 126-134. 10.1016/j.bbrc.2023.04.026. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Mao, Z.W.; Xia, W.; Tao, X. (2021). The crystal structure of SARS-CoV-2 3CLpro with Zinc. Protein Data Bank: 7d64. |
CMCF-BM, CMCF-ID |
PDB Deposition |
Health |
| Ghosh, K. (2024). Human CK1 Delta Kinase structure bound to Inhibitor. Protein Data Bank: 8izc. |
CMCF-ID |
PDB Deposition |
Health |
| Perez-Bermejo, Juan A.; Efagene, Oghene; Matern, William M.; Holden, Jeffrey K.; Kabir, Shaheen et al. (2024). Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair. Nature Communications 15(1) . 10.1038/s41467-024-46816-5. [PDB: 8svg, 8svh, 8svi] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Partridge, J.R.; Holden, J.K.; Wibowo, A.S.; Mulichak, A. (2024). Ubiquitin variant i53:Mutant L67H with 53BP1 Tudor domain. Protein Data Bank: 8svi. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Holden, J.K.; Partridge, J.R.; Wibowo, A.S.; Mulichak, A. (2024). Ubiquitin variant i53 mutant L67R bound to 53BP1 Tudor Domain. Protein Data Bank: 8svh. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Holden, J.K.; Partridge, J.R.; Wibowo, A.S.; Mulichak, A. (2024). Ubiquitin variant i53 in complex with 53BP1 Tudor domain. Protein Data Bank: 8svg. |
CMCF-ID |
PDB Deposition |
Agriculture |
| He, Liqi; Zhang, Meng Yao; Cox, Matthew; Zhang, Qian; Donnell, Andrew F. et al. (2024). Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology. ACS Medicinal Chemistry Letters 15(2) , 189-196. 10.1021/acsmedchemlett.3c00456. [PDB: 8s9h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Wang, F.; Cheng, W.; Yuan, Z.; Qi, J.; Shen, Z. et al. (2024). The Crystal Structure of MAPK2 from Biortus.. Protein Data Bank: 8xu4. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Wang, F.; Cheng, W.; Yuan, Z.; Lin, D.; Ni, C. et al. (2024). The Crystal Structure of TTBK1 from Biortus.. Protein Data Bank: 8xpz. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Wang, F.; Cheng, W.; Yuan, Z.; Lin, D.; Bao, C. et al. (2024). The Crystal Structure of EHMT1 from Biortus.. Protein Data Bank: 8xpt. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Wang, F.; Cheng, W.; Yuan, Z.; Lin, D.; Bao, C. et al. (2024). The Crystal Structure of SRC from Biortus.. Protein Data Bank: 8xn8. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 crystal structure with fragment bound (compound 14). Protein Data Bank: 8t5m. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 co-crystal structure with fragment bound (compound 12). Protein Data Bank: 8t5g. |
CMCF-ID |
PDB Deposition |
Agriculture |