Publication Beamlines Strategic Pillar
White, E. Railey; Sun, Luxin; Ma, Zhong; Beckta, Jason M.; Danzig, Brittany A. et al. (2015). Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain. ACS Chemical Biology 10(5) , 1198-1208. 10.1021/cb500757u. [PDB: 4ofb] CMCF-BM, CMCF-ID Health
van Straaten, Karin E.; Kuttiyatveetil, Jijin R. A.; Sevrain, Charlotte M.; Villaume, Sydney A.; Jiménez-Barbero, Jesús et al. (2015). Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase from Mycobacterium tuberculosis Using Substrate and Tetrafluorinated Substrate Analogues. Journal of the American Chemical Society 137(3) , 1230-1244. 10.1021/ja511204p. [PDB: 4rpg, 4rph, 4rpj, 4rpk, 4rpl] CMCF-ID Health
Vadlamani, Grishma; Thomas, Misty D.; Patel, Trushar R.; Donald, Lynda J.; Reeve, Thomas M. et al. (2015). The β-Lactamase Gene Regulator AmpR Is a Tetramer That Recognizes and Binds the d-Ala-d-Ala Motif of Its Repressor UDP-N-acetylmuramic Acid (MurNAc)-pentapeptide. Journal of Biological Chemistry 290(5) , 2630-2643. 10.1074/jbc.m114.618199. [PDB: 4wkm] CMCF-ID Health
Taylor, Alexander M.; Vaswani, Rishi G.; Gehling, Victor S.; Hewitt, Michael C.; Leblanc, Yves et al. (2015). Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains. ACS Medicinal Chemistry Letters 7(2) , 145-150. 10.1021/ml500411h. [PDB: 4z1s] CMCF-ID Health
Szewczyk, Paul; Tao, Houchao; McGrath, Aaron P.; Villaluz, Mark; Rees, Steven D. et al. (2015). Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein. Acta Crystallographica Section D Biological Crystallography 71(3) , 732-741. 10.1107/s1399004715000978. [PDB: 4q9i, 4q9j, 4q9l] CMCF-ID Health
Ren, Li; Grina, Jonas; Moreno, David; Blake, James F.; Gaudino, John J. et al. (2015). Discovery of Highly Potent, Selective, and Efficacious Small Molecule Inhibitors of ERK1/2. Journal of Medicinal Chemistry 58(4) , 1976-1991. 10.1021/jm501921k. [PDB: 4xj0] CMCF-ID Health
Parker, Aulma; Petluru, Pavankumar; Nienaber, Vicki; Badger, John; Leverett, Betsy et al. (2015). Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787. Molecules 20(3) , 4928-4950. 10.3390/molecules20034928. CMCF-ID Health
Lugo, Miguel R.; Merrill, A. Rod (2015). Pocket analysis of the full-length cholix toxin. An assessment of the structure–dynamics of theapocatalytic domain. Journal of Biomolecular Structure and Dynamics 33(11) , 2452-2468. 10.1080/07391102.2014.1000972. CMCF-ID Health
Loewen, Peter C.; Villanueva, Jacylyn; Switala, Jacek; Donald, Lynda J.; Ivancich, Anabella et al. (2015). Unprecedented access of phenolic substrates to the heme active site of a catalase: Substrate binding and peroxidase-like reactivity ofBacillus pumiluscatalase monitored by X-ray crystallography and EPR spectroscopy. Proteins: Structure. Function and Bioinformatics 83(5) , 853-866. 10.1002/prot.24777. [PDB: 4qol, 4qom, 4qon, 4qoo, 4qop, 4qoq] CMCF-ID Health
Liu, Yiyi; Khalili Najafabadi, Bahareh; Azizpoor Fard, Mahmood; Corrigan, John F. (2015). A Functionalized Ag2S Molecular Architecture: Facile Assembly of the Atomically Precise Ferrocene-Decorated Nanocluster [Ag74S19(dppp)6(fc(C{O}OCH2CH2S)2)18]. Angewandte Chemie 127(16) , 4914-4917. 10.1002/ange.201411944. CMCF-BM, CMCF-ID Materials
Krska, Daniel; Ravulapalli, Ravikiran; Fieldhouse, Robert J.; Lugo, Miguel R.; Merrill, A. Rod et al. (2015). C3larvin Toxin, an ADP-ribosyltransferase from Paenibacillus larvae. Journal of Biological Chemistry 290(3) , 1639-1653. 10.1074/jbc.m114.589846. [PDB: 4tr5] CMCF-ID Health
Helliwell, John R.; Mitchell, Edward P. (2015). Synchrotron radiation macromolecular crystallography: science and spin-offs. IUCrJ 2(2) , 283-291. 10.1107/s205225251402795x. CMCF-ID Materials
Gritzalis, Dimitrios; Park, Jaeok; Chiu, Wei; Cho, Hyungjun; Lin, Yih-Shyan et al. (2015). Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase. Bioorganic and Medicinal Chemistry Letters 25(5) , 1117-1123. 10.1016/j.bmcl.2014.12.089. [PDB: 4qxs] CMCF-ID Health
Frandoloso, Rafael; Martínez-Martínez, Sonia; Calmettes, Charles; Fegan, Jamie; Costa, Estela et al. (2015). Nonbinding Site-Directed Mutants of Transferrin Binding Protein B Exhibit Enhanced Immunogenicity and Protective Capabilities. Infection and Immunity 83(3) , 1030-1038. 10.1128/iai.02572-14. [PDB: 4o3w, 4o3x, 4o3y, 4o3z, 4o49, 4o4u, 4o4x] CMCF-BM, CMCF-ID Health
Doores, Katie J.; Kong, Leopold; Krumm, Stefanie A.; Le, Khoa M.; Sok, Devin et al. (2015). Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope. Journal of Virology 89(2) , 1105-1118. 10.1128/jvi.02905-14. [PDB: 4rnr] CMCF-ID Health