Publication Beamlines Strategic Pillar
Arnal, Gregory; Stogios, Peter J.; Asohan, Jathavan; Attia, Mohamed A.; Skarina, Tatiana et al. (2019). Substrate specificity, regiospecificity, and processivity in glycoside hydrolase family 74. Journal of Biological Chemistry 294(36) , jbc.RA119.009861. 10.1074/jbc.ra119.009861. [PDB: 6p2l, 6p2o] CMCF-ID Health
Wrobleski, Stephen T.; Moslin, Ryan; Lin, Shuqun; Zhang, Yanlei; Spergel, Steven et al. (2019). Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165. Journal of Medicinal Chemistry 62(20) . 10.1021/acs.jmedchem.9b00444. [PDB: 6nzq, 6nzr] CMCF-ID Health
Schrag, Joseph D.; Picard, Marie-Ève; Gaudreault, Francis; Gagnon, Louis-Patrick; Baardsnes, Jason et al. (2019). Binding symmetry and surface flexibility mediate antibody self-association. mAbs 11(7) , 1-19. 10.1080/19420862.2019.1632114. [PDB: 6mxr, 6mxs, 6my4, 6my5] CMCF-ID Health
Kuatsjah, Eugene; Verstraete, Meghan M.; Kobylarz, Marek J.; Liu, Alvin K.N.; Murphy, Michael E.P. et al. (2019). Identification of functionally important residues and structural features in a bacterial lignostilbene dioxygenase. Journal of Biological Chemistry 294(35) , jbc.RA119.009428. 10.1074/jbc.ra119.009428. [PDB: 6ojt] CMCF-ID Health
Lu, Zhonghui; Duan, James J.-W.; Xiao, Haiyun; Neels, James; Wu, Dauh-Rurng et al. (2019). Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonists. Bioorganic and Medicinal Chemistry Letters 29(16) . 10.1016/j.bmcl.2019.06.036. [PDB: 6p9f] CMCF-ID Health
Hobbs, Joanne K.; Pluvinage, Benjamin; Robb, Melissa; Smith, Steven P.; Boraston, Alisdair B. et al. (2019). Two complementary α-fucosidases from Streptococcus pneumoniae promote complete degradation of host-derived carbohydrate antigens. Journal of Biological Chemistry 294(34) , jbc.RA119.009368. 10.1074/jbc.ra119.009368. [PDB: 6or4] CMCF-BM, CMCF-ID Health
Caveney, Nathanael A.; Pavlin, Anja; Caballero, Guillermo; Bahun, Miha; Hodnik, Vesna et al. (2019). Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor. Structure 27(7) . 10.1016/j.str.2019.03.019. [PDB: 6n7o] CMCF-BM, CMCF-ID Health