Publication Beamlines Strategic Pillar
Yeung, Kap-Sun; Beno, Brett R.; Mosure, Kathy; Zhu, Juliang; Grant-Young, Katherine A. et al. (2018). Structure–Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B Inhibitors. ACS Medicinal Chemistry Letters 9(12) , 1217-1222. 10.1021/acsmedchemlett.8b00379. [PDB: 5qj0] CMCF-ID Health
Yaseen, Ayat; Audette, Gerald F. (2018). Structural flexibility in the Helicobacter pylori peptidyl-prolyl cis,trans-isomerase HP0175 is achieved through an extension of the chaperone helices. Journal of Structural Biology 204(2) , 261-269. 10.1016/j.jsb.2018.08.017. [PDB: 6bhf] CMCF-ID Health
Voth, Kevin A.; Chung, Ivy Yeuk Wah; Straaten, Karin; Li, Lei; Boniecki, Michal T. et al. (2018). The structure of Legionella effector protein LpnE provides insights into its interaction with Oculocerebrorenal syndrome of Lowe ( OCRL ) protein. FEBS Journal 286(4) , 710-725. 10.1111/febs.14710. [PDB: 6deh] CMCF-ID Health
Voth, K.; Chung, I.Y.W.; van Straaten, K.E.; Cygler, M. (2018). Structure of LpnE Effector Protein from Legionella pneumophila (sp. Philadelphia). Protein Data Bank: 6deh. CMCF-ID Health
Tomlinson, Aidan (2018). Coronavirus Evolution and Immune Evasion. Supervisor: Rini, James. ON, Canada: University of Toronto. http://hdl.handle.net/1807/102829. CMCF-ID Health
Tanaka, Hiroshi; Sase, Hitoshi; Tsukaguchi, Toshiyuki; Hasegawa, Masami; Tanimura, Hiromi et al. (2018). Selective TRK Inhibitor CH7057288 against TRK Fusion-Driven Cancer. Molecular Cancer Therapeutics 17(12) , 2519-2529. 10.1158/1535-7163.mct-17-1180. [PDB: 5wr7] CMCF-ID Health
Sheriff, S. (2018). CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS GENOTYPE 2A STRAIN JFH1 NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 6-[ethyl(methylsulfonyl)amino]-2-(4-fluorophenyl)-N-methyl-5-(3-{[1-(pyrimidin-2-yl)cyclopropyl]carbamoyl}phenyl)-1-benzofuran-3-carboxamide. Protein Data Bank: 5qj0. CMCF-ID Health
Reimer, J.M.; Jiang, J.; Harb, I.; Schmeing, T.M. (2018). Crystal structure of the formyltransferase PseJ from Anoxybacillus kamchatkensis. Protein Data Bank: 6ci2. CMCF-ID Health
Reimer, J.M.; Harb, I.; Schmeing, T.M. (2018). Crystal structure of the formyltransferase PseJ from Anoxybacillus kamchatkensis in complex with UDP-4,6-dideoxy-4-formamido-L-AltNAc and tetrahydrofolate. Protein Data Bank: 6ci5. CMCF-ID Health
Reimer, Janice M.; Harb, Ingrid; Ovchinnikova, Olga G.; Jiang, Jessie; Whitfield, Chris et al. (2018). Structural Insight into a Novel Formyltransferase and Evolution to a Nonribosomal Peptide Synthetase Tailoring Domain. ACS Chemical Biology 13(11) , 3161-3172. 10.1021/acschembio.8b00739. [PDB: 6ci2, 6ci5] CMCF-ID Health
Ramaswamy, R.; Boulanger, M.J. (2018). Crystal structure of Toxoplasma gondii Mitochondrial Association Factor 1 A (MAF1A). Protein Data Bank: 6bxs. CMCF-ID Agriculture
Murray, J.M.; Rouge, L. (2018). E. coli LepB in complex with GNE0775 ((4S,7S,10S)-10-((S)-4-amino-2-(2-(4-(tert-butyl)phenyl)-4-methylpyrimidine-5-carboxamido)-N-methylbutanamido)-16,26-bis(2-aminoethoxy)-N-(2-iminoethyl)-7-methyl-6,9-dioxo-5,8-diaza-1,2(1,3)-dibenzenacyclodecaphane-4-carboxamide). Protein Data Bank: 6b88. CMCF-ID Health
Marshall, Jeremy D.S.; Mellor, Paul; Ruan, Xuan; Whitecross, Dielle E.; Moore, Stanley A. et al. (2018). Insight into the PTEN - p85α interaction and lipid binding properties of the p85α BH domain. Oncotarget 9(97) , 36975-36992. 10.18632/oncotarget.26432. [PDB: 6mrp] CMCF-BM, CMCF-ID Health
Marshall, Jeremy D.S.; Mellor, Paul; Ruan, Xuan; Whitecross, Dielle E.; Moore, Stanley A. et al. (2018). Insight into the PTEN - p85α interaction and lipid binding properties of the p85α BH domain. Oncotarget 9(97) , 36975-36992. 10.18632/oncotarget.26432. [PDB: 6mrp] CMCF-BM, CMCF-ID Health
Mallette, Evan; Kimber, Matthew S. (2018). Structural and kinetic characterization of (S)-1-amino-2-propanol kinase from the aminoacetone utilization microcompartment of Mycobacterium smegmatis. Journal of Biological Chemistry 293(51) , 19909-19918. 10.1074/jbc.ra118.005485. [PDB: 6ef6] CMCF-ID Health