| Bertwistle, Drew; Vogt, Linda; Aamudalapalli, Hari Babu; Palmer, David R. J.; Sanders, David A. R. et al. (2014). Purification, crystallization and room-temperature X-ray diffraction of inositol dehydrogenase LcIDH2 fromLactobacillus caseiBL23. Acta Crystallographica Section F Structural Biology and Crystallization Communications 70(7) , 979-983. 10.1107/s2053230x14011595. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Blattner, Claudia; Lee, Jeong Hyun; Sliepen, Kwinten; Derking, Ronald; Falkowska, Emilia et al. (2014). Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers. Immunity 40(5) , 669-680. 10.1016/j.immuni.2014.04.008. [PDB: 4nug] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Blattner, C.; Wilson, I.A. (2014). Crystal structure of HIV-1 broadly neutralizing antibody PGT151. Protein Data Bank: 4nug. |
CMCF-ID |
PDB Deposition |
Health |
| De Schutter, Joris W.; Park, Jaeok; Leung, Chun Yuen; Gormley, Patrick; Lin, Yih-Shyan et al. (2014). Multistage Screening Reveals Chameleon Ligands of the Human Farnesyl Pyrophosphate Synthase: Implications to Drug Discovery for Neurodegenerative Diseases. Journal of Medicinal Chemistry 57(13) , 5764-5776. 10.1021/jm500629e. [PDB: 4lpg, 4lph] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Dreyfus, C. (2014). Crystal structure of Fab 3.1 in complex with the 1918 influenza virus hemagglutinin. Protein Data Bank: 4py8. |
CMCF-ID |
PDB Deposition |
Health |
| Elliott, J.Michael; Ultsch, Mark; Lee, Joshua; Tong, Raymond; Takeda, Kentaro et al. (2014). Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2–CH3 Hydrophobic Interaction. Journal of Molecular Biology 426(9) , 1947-1957. 10.1016/j.jmb.2014.02.015. [PDB: 4nqt] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Grishin, Andrey M.; Condos, Tara E.C.; Barber, Kathryn R.; Campbell-Valois, François-Xavier; Parsot, Claude et al. (2014). Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG. Structure 22(6) , 878-888. 10.1016/j.str.2014.04.010. [PDB: 4q5e, 4q5h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gruninger, Robert J.; Thibault, John; Capeness, Michael J.; Till, Robert; Mosimann, Steven C. et al. (2014). Structural and Biochemical Analysis of a Unique Phosphatase from Bdellovibrio bacteriovorus Reveals Its Structural and Functional Relationship with the Protein Tyrosine Phosphatase Class of Phytase. PLoS ONE 9(4) , e94403. 10.1371/journal.pone.0094403. [PDB: 4nx8] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Haji-Ghassemi, O.; Evans, S.V. (2014). Unliganded 3 crystal structure of S25-26 Fab. Protein Data Bank: 4ma1. |
CMCF-ID |
PDB Deposition |
Health |
| Haji-Ghassemi, O.; Evans, S.V. (2014). Unliganded 2 crystal structure of S25-26 Fab. Protein Data Bank: 4m93. |
CMCF-ID |
PDB Deposition |
Health |
| Haji-Ghassemi, O.; Evans, S.V.; Muller-Loennies, S.; Saldova, R.; Muniyappa, M. et al. (2014). Unliganded 1 crystal structure of S25-26 Fab. Protein Data Bank: 4m7z. |
CMCF-ID |
PDB Deposition |
Health |
| Haji-Ghassemi, O.; Evans, S.V.; Muller-Loennies, S.; Saldova, R.; Muniyappa, M. et al. (2014). Crystal structure of S25-26 in complex with Kdo(2.8)Kdo(2.4)Kdo trisaccharide. Protein Data Bank: 4m7j. |
CMCF-ID |
PDB Deposition |
Health |
| Haji-Ghassemi, Omid; Müller-Loennies, Sven; Saldova, Radka; Muniyappa, Mohankumar; Brade, Lore et al. (2014). Groove-type Recognition of Chlamydiaceae-specific Lipopolysaccharide Antigen by a Family of Antibodies Possessing an Unusual Variable Heavy Chain N-Linked Glycan. Journal of Biological Chemistry 289(24) , 16644-16661. 10.1074/jbc.m113.528224. [PDB: 4m7j, 4m7z, 4m93, 4ma1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Johnson, Ted W.; Richardson, Paul F.; Bailey, Simon; Brooun, Alexei; Burke, Benjamin J. et al. (2014). Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations. Journal of Medicinal Chemistry 57(11) , 4720-4744. 10.1021/jm500261q. [PDB: 4ctb] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Kimlicka, Lynn (2014). Structural and biochemical characterizations of the skeletal muscle and cardiac ryanodine receptor N-terminal disease-associated mutants. Supervisor: Van Petegem, Filip. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/46392. |
CMCF-ID |
Doctoral Thesis |
Health |