| Loewen, Peter C.; Carpena, Xavi; Vidossich, Pietro; Fita, Ignacio; Rovira, Carme et al. (2014). An Ionizable Active-Site Tryptophan Imparts Catalase Activity to a Peroxidase Core. Journal of the American Chemical Society 136(20) , 7249-7252. 10.1021/ja502794e. [PDB: 5syh, 5syk] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| McTigue, M.A.; Deng, Y.L.; Liu, W.; Brooun, A.; Stewart, A.E. et al. (2014). Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor (5R)-8-amino-3-fluoro-5,19-dimethyl-20-oxo-5,18,19,20- tetrahydro-7,11-(azeno)pyrido(2',1':2,3)imidazo(4,5-h)(2,5,11) benzoxadiazacyclotetradecine-14-carbonitrile. Protein Data Bank: 4ctb. |
CMCF-ID |
PDB Deposition |
Health |
| Oh, Angela; Ho, Yen-Ching; Zak, Mark; Liu, Yongbo; Chen, Xukun et al. (2014). Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase. ChemBioChem 15(8) , 1121-1130. 10.1002/cbic.201402023. [PDB: 4o0z, 4o10] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Oh, A.; Wang, W. (2014). Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase. Protein Data Bank: 4o0z. |
CMCF-ID |
PDB Deposition |
Health |
| Oh, A.; Wang, W. (2014). Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase. Protein Data Bank: 4o10. |
CMCF-ID |
PDB Deposition |
Health |
| Park, J.; Leung, C.Y.; Tsantrizos, Y.S.; Berghuis, A.M. (2014). Crystal structure of human FPPS in complex with CL03093. Protein Data Bank: 4lph. |
CMCF-ID |
PDB Deposition |
Health |
| Park, J.; Leung, C.Y.; Tsantrizos, Y.S.; Berghuis, A.M. (2014). Crystal structure of human FPPS in complex with CL01131. Protein Data Bank: 4lpg. |
CMCF-ID |
PDB Deposition |
Health |
| Persch, E.; Bryson, S.; Pai, E.F.; Krauth-Siegel, R.L.; Diederich, F. et al. (2014). Crystal structure of Trypanothione Reductase from Trypanosoma brucei in complex with inhibitor EP127 (5-{5-[1-(PYRROLIDIN-1-YL)CYCLOHEXYL]-1,3-THIAZOL-2-YL}-1H-INDOLE). Protein Data Bank: 4nev. |
CMCF-ID |
PDB Deposition |
Health |
| Recht, Michael I.; Sridhar, Vandana; Badger, John; Bounaud, Pierre-Yves; Logan, Cheyenne et al. (2014). Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography. Journal of Biomolecular Screening 19(4) , 497-507. 10.1177/1087057113516493. [PDB: 4mrw, 4mrz, 4ms0, 4msa, 4msc, 4mse] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Sridar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; Nienaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT0449 (5-nitro-1H-benzimidazole). Protein Data Bank: 4msa. |
CMCF-ID |
PDB Deposition |
Health |
| Sridhar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; Nienaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT1595 (2-[(quinolin-7-yloxy)methyl]quinoline). Protein Data Bank: 4msc. |
CMCF-ID |
PDB Deposition |
Health |
| Sridhar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; Nienaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT1597 (2-({[(2S)-2-methyl-2,3-dihydro-1,3-benzothiazol-5-yl]oxy}methyl)quinoline). Protein Data Bank: 4mse. |
CMCF-ID |
PDB Deposition |
Health |
| Sridhar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; Nienaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT0443 (6-chloropyrimidine-2,4-diamine). Protein Data Bank: 4ms0. |
CMCF-ID |
PDB Deposition |
Health |
| Sridhar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; Nienaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT0429 (4-methyl-3-nitropyridin-2-amine). Protein Data Bank: 4mrz. |
CMCF-ID |
PDB Deposition |
Health |
| Sridhar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; NIenaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT0120 (7-chloroquinolin-4-ol). Protein Data Bank: 4mrw. |
CMCF-ID |
PDB Deposition |
Health |