Publication Beamlines Strategic Pillar
Bonday, Zahid Q.; Cortez, Guillermo S.; Grogan, Michael J.; Antonysamy, Stephen; Weichert, Ken et al. (2018). LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity. ACS Medicinal Chemistry Letters 9(7) , 612-617. 10.1021/acsmedchemlett.8b00014. [PDB: 6ckc] CMCF-ID Health
Huang, Christine S.; Oberbeck, Nina; Hsiao, Yi-Chun; Liu, Peter; Johnson, Adam R. et al. (2018). Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity. Structure 26(5) , 767-777.e5. 10.1016/j.str.2018.04.002. [PDB: 5wni] CMCF-ID Health
Bagal, Sharan K.; Omoto, Kiyoyuki; Blakemore, David C.; Bungay, Peter J.; Bilsland, James G. et al. (2018). Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors. Journal of Medicinal Chemistry 62(1) , 247-265. 10.1021/acs.jmedchem.8b00280. [PDB: 6d20] CMCF-ID Health
Gebai, Ahmad; Gorelik, Alexei; Li, Zixian; Illes, Katalin; Nagar, Bhushan et al. (2018). Structural basis for the activation of acid ceramidase. Nature Communications 9(1) . 10.1038/s41467-018-03844-2. [PDB: 5u7z, 5u81, 5u84] CMCF-BM, CMCF-ID Health
Jacques, Benoit; Coinçon, Mathieu; Sygusch, Jurgen (2018). Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases. Journal of Biological Chemistry 293(20) , 7737-7753. 10.1074/jbc.ra117.001098. [PDB: 5ucn, 5ucp, 5ucs, 5ucz, 5ud0, 5ud1, 5ud2] CMCF-BM, CMCF-ID Health
Yaseen; Ayat (2018). Part I: Crystallization of A Type IV Pilin from Pseudomonas Aeruginosa. Part II: Characterization of a Peptidyl-Prolyl-Cis,Trans-Isomerase Through X-Ray Crystallography. Supervisor: Audette, Gerald F. Ontario, Canada: York University. http://hdl.handle.net/10315/34570. CMCF-BM, CMCF-ID Agriculture
Joan Seoane Suarez; Judit Anido Folgueira; Johan Fransson; Jean-Philippe Julien; Swetha RAMAN et al. (2018). Antibodies against lif and uses thereof. Patent Number: US20180169233A1. CMCF-ID Health
Gajiwala, K.S.; Johnson, E.; Cronin, C.N. (2018). Structure of the PTK6 kinase domain. Protein Data Bank: 6cz2. CMCF-ID Health
Gajiwala, K.S.; Johnson, E.; Cronin, C.N. (2018). Structure of the PTK6 kinase domain bound to a type I inhibitor (3-fluoro-4-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone. Protein Data Bank: 6cz3. CMCF-ID Health
Scally, S.W.; Bosch, A.; Imkeller, K.; Wardemann, H.; Julien, J.P. et al. (2018). Crystal structure of 1450 Fab in complex with circumsporozoite protein NANP5. Protein Data Bank: 6d11. CMCF-ID Health
Scally, S.W.; Bosch, A.; Imkeller, K.; Wardemann, H.; Julien, J.P. et al. (2018). Crystal structure of 1210 Fab in complex with circumsporozoite protein NANP5. Protein Data Bank: 6d01. CMCF-ID Health
Gebai, A.; Gorelik, A.; Illes, K.; Nagar, B. (2018). Murine saposin-D (SapD), open conformation. Protein Data Bank: 5u85. CMCF-ID Agriculture
Alexander, J.A.N.; Strynadka, N.C.J. (2018). Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with nafcillin. Protein Data Bank: 5ty7. CMCF-ID Health
Ulaganathan, T.; Cygler, M. (2018). Complex structure of Ulvan lyase from Nonlaben Ulvanivorans- NLR48. Protein Data Bank: 6d3u. CMCF-ID Agriculture
Mallette, E.; Kimber, M.S. (2018). RMM microcompartment-associated aminopropanol dehydrogenase NADP + aminoacetone holo-structure. Protein Data Bank: 6ci9. CMCF-ID Agriculture