| Kolesnikov, M.; Murphy, M.E.P. (2019). Crystal structure of Fusobacterium nucleatum flavodoxin mutant K13G bound to flavin mononucleotide. Protein Data Bank: 6ohk. |
CMCF-ID |
PDB Deposition |
Health |
| Yachnin, B.J.; Berghuis, A.M. (2019). Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor. Protein Data Bank: 6ny0. |
CMCF-ID |
PDB Deposition |
Health |
| Bryan, Marian C.; Drobnick, Joy; Gobbi, Alberto; Kolesnikov, Aleksandr; Chen, Yongsheng et al. (2019). Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors. Journal of Medicinal Chemistry 62(13) . 10.1021/acs.jmedchem.9b00439. [PDB: 6o9d] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Yu, C.; Drobnick, J.; Bryan, M.C.; Kiefer, J.; Lupardus, P.J. et al. (2019). Structure of the IRAK4 kinase domain with compound 5. Protein Data Bank: 6o9d. |
CMCF-ID |
PDB Deposition |
Health |
| Sack, J.S. (2019). Crystal structure of JAK3 kinase domain in complex with a pyrrolopyridazine carboxamide inhibitor. Protein Data Bank: 6ny4. |
CMCF-ID |
PDB Deposition |
Health |
| Garside, E.L.; MacMillan, A.M. (2019). Prp8 RH domain from C. merolae. Protein Data Bank: 6nqi. |
CMCF-ID |
PDB Deposition |
Health |
| Garside, E.L.; Whelan, T.A.; Stark, M.R.; Rader, S.D.; Fast, N.M. et al. (2019). Prp8 in a Reduced Spliceosome Lacks a Conserved Toggle that Correlates with Splicing Complexity across Diverse Taxa. Journal of Molecular Biology 431(14) . 10.1016/j.jmb.2019.04.047. [PDB: 6nqi] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Fenalti, G. (2019). Crystal structure of the human TTK in complex with an inhibitor. Protein Data Bank: 6n6o. |
CMCF-ID |
PDB Deposition |
Health |
| Riggs, Jennifer R.; Elsner, Jan; Cashion, Dan; Robinson, Dale; Tehrani, Lida et al. (2019). Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy. Journal of Medicinal Chemistry 62(9) , 4401-4410. 10.1021/acs.jmedchem.8b01869. [PDB: 6n6o] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Halgas, O.; Zarabi, S.F.; Schimmer, A.; Pai, E.F. (2019). Human mitochondrial ClpP in complex with ONC201 (TIC10). Protein Data Bank: 6dl7. |
CMCF-ID |
PDB Deposition |
Health |
| Ishizawa, Jo; Zarabi, Sarah F.; Davis, R. Eric; Halgas, Ondrej; Nii, Takenobu et al. (2019). Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality. Cancer Cell 35(5) . 10.1016/j.ccell.2019.03.014. [PDB: 6dl7] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Lei, M.; Tempel, W.; Arrowsmith, C.H.; Bountra, C.; Edwards, A.M. et al. (2019). MeCP2 MBD in complex with DNA. Protein Data Bank: 6ogj. |
CMCF-ID |
PDB Deposition |
Health |
| Fischmann, T.O. (2019). Murine PI3K delta kinsae domain - cpd 1. Protein Data Bank: 6mul. |
CMCF-ID |
PDB Deposition |
Health |
| Methot, Joey L.; Zhou, Hua; Kattar, Sam D.; McGowan, Meredeth A.; Wilson, Kevin et al. (2019). Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability. Journal of Medicinal Chemistry 62(9) . 10.1021/acs.jmedchem.8b01818. [PDB: 6mul] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Guarne, A.; Almawi, A.W. (2019). Crystal structure of the Escherichia coli sliding clamp-MutL complex.. Protein Data Bank: 6e8e. |
CMCF-ID |
PDB Deposition |
Health |