Publication Beamlines Strategic Pillar
Davies, Christopher W.; Stowe, Irma; Phung, Qui T.; Ho, Hoangdung; Bakalarski, Corey E. et al. (2021). Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function. Proceedings of the National Academy of Sciences of the United States of America 118(12) , e2018024118. 10.1073/pnas.2018024118. [PDB: 7jwq] CMCF-ID Health
Mulligan, Vikram Khipple; Workman, Sean; Sun, Tianjun; Rettie, Stephen; Li, Xinting et al. (2021). Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1. Proceedings of the National Academy of Sciences of the United States of America 118(12) , e2012800118. 10.1073/pnas.2012800118. [PDB: 6xbe, 6xbf] CMCF-ID Health
Wang, F.; Xu, C.; Qi, J.; Zhang, M.; Tian, F. et al. (2021). The Crystal Structure of D-psicose-3-epimerase from Biortus.. Protein Data Bank: 7e9w. CMCF-ID Health
Wang, F.; Lin, D.; Wang, R.; Wei, X.; Shen, Z. et al. (2021). The Crystal Structure of human UMP-CMP kinase from Biortus.. Protein Data Bank: 7e9v. CMCF-ID Health
Payandeh, J.; Ho, H. (2021). Fab CJ11 in complex IL-1beta peptide liberated by Caspase cleavage. Protein Data Bank: 7jwq. CMCF-ID Health
Sintchak, M.; Lane, W.; Bump, N. (2021). Structure of SUMO1-ML00789344 adduct bound to SAE. Protein Data Bank: 6xoh. CMCF-ID Health
Swinger, K.K.; Schenkel, L.B.; Kuntz, K.W. (2021). Human PARP14 (ARTD8), catalytic fragment in complex with RBN012759. Protein Data Bank: 6we2. CMCF-ID Health
Burke, J.E.; Rathinaswamy, M.K.; Harris, N.J. (2021). Gedatolisib bound to the PI3Kg catalytic subunit p110 gamma. Protein Data Bank: 7jwe. CMCF-ID Health
Burke, J.E.; Rathinaswamy, M.K.; Harris, N.J. (2021). NVS-PI3-4 bound to the PI3Kg catalytic subunit p110 gamma. Protein Data Bank: 7jx0. CMCF-ID Health
Burke, J.E.; Rathinaswamy, M.K.; Harris, N.J. (2021). IPI-549 bound to the PI3Kg catalytic subunit p110 gamma. Protein Data Bank: 7jwz. CMCF-ID Health
Rathinaswamy, Manoj K; Gaieb, Zied; Fleming, Kaelin D; Borsari, Chiara; Harris, Noah J et al. (2021). Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors. eLife 10. 10.7554/elife.64691. [PDB: 7jwe, 7jwz, 7jx0] CMCF-ID Health
Cygler, M.; Chung, I.Y.W. (2021). Structure of RavA (lpp0008) E38A/K39A surface entropy reduction mutant. Protein Data Bank: 6wo6. CMCF-ID Health
Chung, Ivy Y. W.; Li, Lei; Tyurin, Oleg; Gagarinova, Alla; Wibawa, Raissa et al. (2021). Structural and functional study of Legionella pneumophila effector RavA. Protein Science 30(5) . 10.1002/pro.4057. [PDB: 6wo6] CMCF-ID Health
Sintchak, M.; Lane, W.; Bump, N. (2021). Structure of SUMO1-ML786519 adduct bound to SAE. Protein Data Bank: 6xog. CMCF-ID Health
Langston, Steven P.; Grossman, Stephen; England, Dylan; Afroze, Roushan; Bence, Neil et al. (2021). Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. Journal of Medicinal Chemistry 64(5) . 10.1021/acs.jmedchem.0c01491. [PDB: 6xog, 6xoh] CMCF-ID Health