Publication Beamlines Strategic Pillar
Bacik, John-Paul; Tavassoli, Marjan; Patel, Trushar R.; McKenna, Sean A.; Vocadlo, David J. et al. (2014). Conformational Itinerary of Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase during Its Catalytic Cycle. Journal of Biological Chemistry 289(7) , 4504-4514. 10.1074/jbc.m113.521633. [PDB: 4mo4, 4mo5] CMCF-ID Health
Grishin, Andrey M.; Cherney, Maia; Anderson, Deborah H.; Phanse, Sadhna; Babu, Mohan et al. (2014). NleH Defines a New Family of Bacterial Effector Kinases. Structure 22(2) , 250-259. 10.1016/j.str.2013.11.006. [PDB: 4lrj, 4lrk] CMCF-ID Health
Jacobson, Jared M.; Yin, Jiang; Kitov, Pavel I.; Mulvey, George; Griener, Tom P. et al. (2014). The Crystal Structure of Shiga Toxin Type 2 with Bound Disaccharide Guides the Design of a Heterobifunctional Toxin Inhibitor. Journal of Biological Chemistry 289(2) , 885-894. 10.1074/jbc.m113.518886. [PDB: 4m1u] CMCF-ID Health
Keeling, Thomas J.; Samborska, Bożena; Demers, Ryan W.; Kimber, Matthew S. (2014). Interactions and structural variability of β-carboxysomal shell protein CcmL. Photosynthesis Research 121(2-3) , 125-133. 10.1007/s11120-014-9973-z. [PDB: 4n8f, 4n8x] CMCF-ID Materials
Keszei, Alexander F. A.; Tang, Xiaojing; McCormick, Craig; Zeqiraj, Elton; Rohde, John R. et al. (2014). Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase. Molecular and Cellular Biology 34(3) , 362-373. 10.1128/mcb.01360-13. [PDB: 4nkg] CMCF-ID Health
Kiefer, Susan E.; Chang, ChiehYing J.; Kimura, S. Roy; Gao, Mian; Xie, Dianlin et al. (2014). The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor. Acta Crystallographica Section F Structural Biology and Crystallization Communications 70(2) , 173-181. 10.1107/s2053230x14000144. [PDB: 4nfm] CMCF-ID Health
Lee, Jaeyong; Taneva, Svetla G.; Holland, Bryan W.; Tieleman, D. Peter; Cornell, Rosemary B. et al. (2014). Structural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic Helix. Journal of Biological Chemistry 289(3) , 1742-1755. 10.1074/jbc.m113.526970. [PDB: 4mvc, 4mvd] CMCF-BM, CMCF-ID Health
Lewis, Steven M; Wu, Xiufeng; Pustilnik, Anna; Sereno, Arlene; Huang, Flora et al. (2014). Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nature Biotechnology 32(2) , 191-198. 10.1038/nbt.2797. [PDB: 4lld] CMCF-ID Health
Parker, Matthew J; Gomery, Kathryn; Richard, Gabrielle; MacKenzie, C Roger; Cox, Andrew D et al. (2014). Structural basis for selective cross-reactivity in a bactericidal antibody against inner core lipooligosaccharide from Neisseria meningitidis†,‡. Glycobiology 24(5) , 442-449. 10.1093/glycob/cwu009. [PDB: 4c83, 4rqx] CMCF-ID Health
Park, Jaeok; Lin, Yih-Shyan; Tsantrizos, Youla S.; Berghuis, Albert M. (2014). Structure of human farnesyl pyrophosphate synthase in complex with an aminopyridine bisphosphonate and two molecules of inorganic phosphate. Acta Crystallographica Section F Structural Biology and Crystallization Communications 70(3) , 299-304. 10.1107/s2053230x14002106. [PDB: 4lfv] CMCF-ID Health
Thi, Nhung Nguyen; Offen, Wendy A.; Shareck, François; Davies, Gideon J.; Doucet, Nicolas et al. (2014). Structure and Activity of the Streptomyces coelicolor A3(2) β-N-Acetylhexosaminidase Provides Further Insight into GH20 Family Catalysis and Inhibition. Biochemistry 53(11) , 1789-1800. 10.1021/bi401697j. [PDB: 4c7f] CMCF-ID Health
Vidossich, Pietro; Loewen, Peter C.; Carpena, Xavi; Fiorin, Giacomo; Fita, Ignacio et al. (2014). Binding of the Antitubercular Pro-Drug Isoniazid in the Heme Access Channel of Catalase-Peroxidase (KatG). A Combined Structural and Metadynamics Investigation. Journal of Physical Chemistry B 118(11) , 2924-2931. 10.1021/jp4123425. [PDB: 5syi] CMCF-ID Health
Yao, Deqiang; Cherney, Maia; Cygler, Miroslaw (2014). Structure of the N-terminal domain of the effector protein LegC3 fromLegionella pneumophila. Acta Crystallographica Section D Biological Crystallography 70(2) , 436-441. 10.1107/s139900471302991x. [PDB: 4mu6] CMCF-ID Health
Zheng, Xiaozhang; Baumeister, Timm; Buckmelter, Alexandre J.; Caligiuri, Maureen; Clodfelter, Karl H. et al. (2014). Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors. Bioorganic and Medicinal Chemistry Letters 24(1) , 337-343. 10.1016/j.bmcl.2013.11.006. [PDB: 4lww] CMCF-ID
Krska, Daniel (2014). Larvin: The characterization of a novel mono-ADP-ribosyltransferase toxin. Supervisor: Merrill, Rod. Ontario, Canada: The University of Guelph. CMCF-ID Health